Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Rhinosporidiosis in tracheobronchial tree is extremely rare. It poses diagnostic and therapeutic challenges and has high chance of mortality because of presentation with respiratory distress. We report such a case of a 35 years old man who presented with respiratory distress and dry irritating cough. Fiberoptic laryngoscopy revealed a reddish soft tissue mass below the vocal cord level. Magnetic Resonance Imaging showed a soft tissue opacity within the trachea occluding the airway. Direct endoscopic biopsy was done after securing the airway. Histopathological examination confirmed rhinosporidiosis and the mass was excised through an external approach. The patient was free of symptoms and no recurrence was reported till 30 months of follow-up.
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PMID:Tracheal rhinosporidiosis: an uncommon life threatening benign condition. 2505 80

Rhinosporidiosis is a chronic granulomatous infectious disease caused by Mesomycetozoea Rhinosporidium seeberi. This highly recurrent polypoid lesion has a predilection for the nose and nasopharynx, although other organ systems may be affected. Involvement of the tracheobronchial tree is very rare, and poses a challenge for diagnosis and management. In this report, we present a 30-year-old man with a history of recurrent nasal polyp who presented with cough, shortness of breath, haemoptysis, and a radiological feature of right lung collapse on imaging. He was diagnosed with rhinosporidiosis based on histopathological examination of bronchoscopic biopsy specimen taken from the right principal bronchial mass. Shortly after hospitalization, he developed acute respiratory distress requiring emergency bronchoscopic intervention. A pinkish mulberry-like tracheal and right bronchial mass was removed endoscopically with cauterization of the base of the lesion. On long-term follow-up, the patient was free of symptoms without recurrence of airway disease.
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PMID:Tracheobronchial rhinosporidiosis: an uncommon life-threatening benign cause of airway obstruction. 3287 89