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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Six worm-free pony foals, two to four months old, were infected with parascaris equorum eggs using three different dosage regimes and killed at either 40 or 95-100 days after infection. Coughing and a circulating eosinophilia were features of large infections from which only a small number of worms developed to maturity. In small infections a high percentage of the parasites matured in the small intestine and this was associated with unthriftiness. Pre-patent periods of 80 and 83 days were recorded.
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PMID:Experimental Parascaris equorum infection of foals. 90 41

Many Sri Lankan children with cough and wheeze and peripheral blood eosinophilia are treated with diethyl carbamazine (D.E.C.) on the assumption that filaria is the cause. We tried to establish whether filaria can trigger asthma and whether D.E.C. improves bronchial reactivity. In 35 symptomatic and 22 asymptomatic children peripheral blood eosinophil counts, filarial antibody test, stool examination, chest radiography, allergy skin tests and histamine inhalation tests were performed before and after treatment with D.E.C. Most of the symptomatic children were atopic; 1/3 of all children had helminthiasis, positive filarial antibodies and total eosinophil counts of greater than 2,000. Ten children had chest radiographs suggestive of tropical pulmonary eosinophilia. Only in those with intermittent symptoms was there a marked improvement in bronchial reactivity after D.E.C., but baseline peak expiratory flow (P.E.F.) improved in all symptomatic groups. We conclude that 1/3 of the children had filariasis which in an atopic individual may trigger asthma. Both the anti-inflammatory and the anti-filarial action of D.E.C. probably contribute to improvement of bronchial reactivity.
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PMID:Is filariasis a trigger for bronchial asthma? 211 65

A field trial of 6-monthly ascariasis chemotherapeutic regimens targeted at 1-19-, 1-14-, and 5-19-year-olds was carried out in three communities in rural Myanmar to observe the effects on the prevalence, intensity, and morbidity indicators over 2 years. After periodic chemotherapy, the prevalence and intensity of Ascaris infection in age-targeted and non-age-targeted groups fell in all the study areas, more markedly among the 1-19- and 1-14-year-olds. There was also a decrease in the frequency of vomiting of worms, passing of worms per anus, coughing, abdominal pain and treatment of bowel complaints, especially among the treated groups. In addition, there were reductions in the frequency of fever from nonbowel complaints and protrusion of the abdomen among children in the targeted group.
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PMID:Control of ascariasis through age-targeted chemotherapy: impact of 6-monthly chemotherapeutic regimens. 215 11

The first case of syngamosis in a human in Canada is reported. The patient, a traveller to the Caribbean islands, presented with a chronic dry cough. The nematode Syngamus laryngeus is found in wild and domestic birds and mammals in the tropics and subtropics. Humans are only accidental hosts. The diagnosis of syngamosis is usually made by fibreoptic bronchoscopic examination, which reveals the Y-shaped worms in the bronchi or the characteristic eggs in the sputum or feces. Physicians must be alerted to the possibility of syngamosis in patients with symptoms of asthma who have recently travelled to South America or the Caribbean islands.
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PMID:Syngamosis, an unusual cause of asthma: the first reported case in Canada. 315 41

P. equorum is a common and ubiquitous parasite that persists for many years in stables and on pasture in spite of good hygiene and anthelmintic control programs. Foals are usually infected early in life. During the migratory phase of the infection, clinical signs include coughing and a nasal discharge followed by depression and unthriftiness as the worms mature in the gut. Some foals die as a result of intestinal impaction or rupture. Patency is established around 3 months of age, and fecal egg counts may rise to very high levels. From 6 months of age onwards, the ascarid burden diminishes as the foals become immune. Patent infections are seldom found in mature horses and, when present, they tend to be of low magnitude. Preventive measures are aimed at treating foals frequently enough to prevent the development of a large mass of ascarids in the intestine. This is achieved by a 6-weekly dosing regimen using an anthelmintic with proven and reliable efficacy against P. equorum.
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PMID:Ascarids. Recent advances. 352 75

Infection of humans by Mammomonogamus is rare, with approximately 80 cases reported in the literature. When present in man, the worms cause violent coughing until their removal. The diagnosis of Mammomonogamus infection in the past has been based on morphologic characteristics of intact adults. We report a case diagnosed by features of the worms in histologic section.
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PMID:Mammomonogamus infection in a human. Report of a case. 662 80

The hepatic damage induced by Paragonimus skrjabini, and the migration route of this species and that of P. westermani, were investigated in a series of animal experiments and in 34 clinical and four autopsy cases of paragonimiasis. The major symptoms and signs of an unique case reported from Sichuan Province included hepatic tenderness, disturbance of hepatic functions, remittent fever, and cough with bloody sputum. Laparotomy revealed marked adhesions surrounding the liver, spleen and duodenum. Diagnosis was made by finding P. skrjabini in a bulla on the abdominal wall about 5 months after the onset of illness. After specific treatment with bithional, body temperature and liver functions returned to normal. Twenty-three of 33 cases independently studied from Fujian Province also showed similar hepatic function disturbance. Autopsy cases showed hepatic chronic eosinophilic abscesses with Charcot-Leyden crystals. Experimentally, P. skrjabini infection caused hepatic damage in all laboratory animals used. The main pathologic changes were initially acute eosinophilic abscesses in the liver, worms being found sometimes in the necrotic cavities of the abscesses; hepatomagaly also occurred. Some cysts containing mature worms were found in the liver of dogs 3-9 months after infection. Numerous eggs were deposited in the cyst walls. The migration route of P. skrjabini was studied in young dogs. Worms appeared in the liver initially on day 3 and reached their highest level on day 14. P. westermani also migrated into liver, but their numbers were less than those of P. skrjabini.
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PMID:Hepatic damage in experimental and clinical paragonimiasis. 714 1

Respiratory disease occupies a prominent position in the series of common diseases in calves. Efforts were made to take an inventory of possible causes of cough in calves at pasture. For this purpose, a number of calves on twenty-three, ten and eight mixed farms respectively were clinically studied during the period from 1975 up to and including 1977. Faecal, sputum and serum samples were collected to examine them for the presence of husk worm larvae, husk worm eggs, antibodies to specific viruses and lung worms. In 1978, titres of antibodies to lung worms were determined in the serum samples of a large number of calves from forty-five farms. From the findings obtained, conclusions were drawn regarding the prevention of virus and lung worm infections in calves at pasture and regarding the diagnosis and prevention of verminous bronchitis in these animals.
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PMID:[Studies on the possible causes of cough in calves at pasture (author's transl)]. 744 28

About 100 cases of human infections with Mammomonogamus laryngeus (Syngamidae, Syngaminae) have been reported, with virtually all cases originating in the Caribbean Islands and Brazil. This report describes the fifth patient in North America infected with M. laryngeus and the first case documented to originate in Jamaica. The patient complained of a characteristic persistent nonproductive cough and a lump in her throat. M. laryngeus is a nematode in which the male and female are permanently joined in copula, producing a distinctive Y shape. Since there is scant clinical information about this parasite, this report includes a description of the adult worms and eggs, a summary of the epidemiology, and the clinical manifestations in humans. Illustrations are presented to facilitate future identification of this parasite and to expedite treatment.
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PMID:Case report of and description of parasite in Mammomonogamus laryngeus (human syngamosis) infection. 779 Apr 76

At the two largest open air markets in Kumasi, Ghana, interviews were conducted with 143 women who had at least one child aged less than five years. Researchers wanted to examine their knowledge, attitude, and practices concerning acute respiratory infection (ARI) in children. The women tended to be married, Christian, from the Ashanti tribe, aged 20-29 years, and to have 2-3 living children. 73.4% had a child or children who had suffered from cough and fever within the last six months. 73.4% named exposure to cold as a direct cause of cough. Many women incorrectly blamed worm infestation for causing cough and fever (21%) and constipation for causing cough (25.9%). None mentioned pathogens as a cause of cough and fever. None said that good ventilation and avoidance of overcrowding prevent cough and fever. The more serious the symptoms, the more likely the mothers were to seek treatment at a health care facility (e.g., cough only, 0.7%; cough and fever, 6.3%; cough, fever, and anorexia, 30%; and cough, fever, and lethargy, 57.3%). Common home care practices for treating a runny nose included ephedrine or other types of nasal drops, herbal medicines, antipyretics, and antibiotics. 39.9% would use antibiotics to treat coughs. Honey and cough syrup were often used to treat cough and fever. Some herbal and home care therapies had potentially harmful effects. For example, 25.9% said that they used castor oil and enemas to prevent ARI. The women had an acceptable knowledge score on severity of symptoms (mode = 15/20; range = 11-18). These findings indicate a need for a health education program targeting mothers of children aged less than five years.
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PMID:Maternal knowledge, attitude and practices regarding childhood acute respiratory infections in Kumasi, Ghana. 788 91


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