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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Measurements of thoracic gas volume, airways resistance, and total respiratory resistance were measured in a group of babies with acute severe bronchiolitis. Assessments were made at convalescence, three to four months later, and after 12 months. Clinical histories were also taken 12 months after the acute episode. Results at this time showed that 35% of the infants had coughing attacks, 50% episodes of wheezing, 50% had dry skin or eczema, and that over 75% had lung function abnormality.
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PMID:Lung function abnormalities after acute bronchiolitis. 722 87

The aim of this paper was to study the effect of pets and other domestic animals on bronchial asthma among United Arab Emirates (UAE) schoolchildren aged 6-14 years. A cross-sectional study of 850 schoolchildren living in both urban and rural areas (average age 9.36 +/- 2.11 years, 46.8% boys and 53.2% girls) was conducted using self-administered questionnaires between October 1992 and May 1993. Prevalence rate for asthma, rhinitis, wheeze, cough, and eczema in children from families with and without animals were investigated. A total of 40.7% of families studied were found to keep animals in their homes. Children from families with animals were found to have a significantly higher prevalence rate of respiratory symptoms than those without. The prevalence rate for asthma in children with animals was found to be twice that of children without (RR: 2.03; 95% CI: 1.40-2.95). The risk of having chronic cough (RR: 1.93; 95% CI: 1.21-3.10), breathlessness/chest tightness (RR: 2.53; 95% CI: 1.59-4.02), chronic wheeze (RR: 2.10; 95% CI: 1.20-3.67), allergic rhinitis (RR: 1.53; 95% CI: 1.17-2.00) was significantly higher in children with animals than in children without. Similarly, the risk of having eczema (RR: 2.55; 95%, CI: 1.74-3.75) was significantly higher among children with animals than among those without. Overall, there was a highly statistically significant difference in the prevalence of asthma, wheeze, nocturnal cough, eczema, and rhinitis between children in families with animals and those without (p < 0.0001).(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Pet ownership in the UAE: its effect on allergy and respiratory symptoms. 755 61

We administered a questionnaire to the parents of 832 children in 4th class. 134 had wheezed in the previous 12 months. These children and matched controls were invited to attend for a brief clinical evaluation. 118 children with a history of wheeze and 118 age and sex matched wheeze free controls were seen. A brief questionnaire was administered. Heights and peak flow were measured. Children were assessed for the presence of chest deformity and eczema. There was a male predominance (1.7:1). Exercise induced symptoms were noted by 86% of children, but only 65% of parents in contrast, 65% of parents complained of night cough as against 28% of children. Over half had missed school because of asthma. Controls were asymptomatic. Height and peak flow measurements were similar in both groups. Chest deformity was evident in 25% of children with asthma, 8% had eczema and 27% were taking prophylactic medication. Childrens perception of asthma differs from that of their parents. School absence remains a problem and clinical evidence of hyper-inflation is common, though the absence of an overt effect on height and peak flow is encouraging.
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PMID:Spectrum of childhood asthma in Galway. 810 26

In a cross-sectional study, the prevalence of asthma and wheeze was studied in 2300 school going children in two different environment and climate regions of Saudi Arabia, Dammam (humid-coastal) and Riyadh (dry-inland). The age range of children studied was 7-12 years (56% boys and 44% girls in Dammam; and 47% boys and 53% girls in Riyadh). A self-administered questionnaire was completed by parents of the children which includes information on age, sex, area, occupation and educational level of parents, history of asthma, allergic rhinitis, eczema, cough, wheeze, animals and pets exposure, family history of allergy and parental smoking habits. The results showed that prevalence of wheeze was more common in Riyadh (11.86%) than in Dammam (6.54%). Also, cough occurred more frequently in Riyadh (7.9%) than in Dammam (6%). The frequency of rhinitis was significantly more common in both areas than wheeze (Riyadh 17% and Dammam 12%). Also, the attack of breathlessness or tightness occurred more frequently in Riyadh (12.13%) than in Dammam (6.10%). When a more formal diagnosis of asthma was sought, this having been made by a doctor, the figures were 9.28% for Riyadh and 3.59% for Dammam. These figures showed major differences between the coastal and inland areas in the prevalence of bronchial asthma and wheezing with Dammam being relatively low risk whereas children in Riyadh region describe this more commonly.
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PMID:Prevalence of asthma and wheeze in two different climatic areas of Saudi Arabia. 822 34

In this investigation 98 children (median age 24 months) with cows' milk allergy (CMA) were studied over a median period of 2 years to see whether acquisition of clinical tolerance to cows' milk was associated with the changes in levels of IgG and IgE anti-cows' milk antibodies, and skin test reactivity to a cows' milk extract. Two groups of CMA patients were examined. The first were IgE sensitized and responded rapidly to small volumes of cows' milk with urticaria, and/or exacerbations of eczema, and/or wheeze, and/or vomiting (n = 69). The second, a late reacting group (n = 29) demonstrated coughing, diarrhoea, eczematoid rashes, and/or a combination of these which developed more than 20 hr after commencing normal volumes of cows' milk. Significant immunological changes were confined to the 69 IgE sensitized immediate-reacting-group of patients. Of these, there were 15 children who achieved clinical tolerance to cows' milk and they showed a significant fall in the levels of skin test reactivity to cows' milk over the study period (P < 0.01). In addition, these 15 children had lower serum IgE antibodies to cows' milk proteins both at the outset and the final follow-up compared with the 54 patients whose CMA persisted. No consistent change in the IgG antibody responses to cows' milk proteins was seen in either group of patients over the study period. The findings suggest patients with immediate type hypersensitivity to cows' milk proteins whose disease persists for more than 2 years have a more severe dysregulation of IgE synthesis to cows' milk proteins from the outset.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Natural history of cows' milk allergy in children: immunological outcome over 2 years. 844 85

541 workers with long-term history of occupational contact with antibiotics and chemicals were examined by a dermatologist, ENT specialist, neuropathologist, surgeon, ophthalmologist. Many workers complained of occasional skin eruption, rhinitis, skin itching, sneezing, cough, Quincke's edema. Allergic examination revealed the presence of allergic symptoms (allergic dermatitis, itch, vasomotor rhinitis, chronic eczema, obstructive bronchitis, bronchial asthma, Quincke's edema, acute and chronic conjunctivitis) in 98 examinees. Somatic affections are represented by hypertension, chronic hepatitis, ulcer.
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PMID:[The effect of antibiotics on the body of those working in their manufacture]. 877

The development of symptoms possibly related to allergy or other forms of hypersensitivity was studied in a group of 638 children on two occasions: when the children were 3 and 18 months of age. Standardized questions were used to collect basic information about the child, technical characteristics of the home, and the mother's perception of the indoor climate. All reported exposure factors were analyzed in relation to the child's symptoms at 18 months of age, by logistic regression techniques. A family history of atopy was associated with a high incidence of most of the investigated symptoms. Attendance at a day nursery before 18 months of age increased the risk of recurrent colds and the need for several courses of treatment with antibiotics. If the mother smoked, the children more often suffered from protracted coughing episodes. If the child has a sibling, the risk of developing a wheeze, repeated colds, and the need for antibiotic treatment increased. No building factors, such as size of the home, heating and ventilation system, type of foundation, dampness, or presence of wall-to-wall carpets, showed a significant correlation to symptoms reported in the children. However, if the mothers reported symptoms that are often connected with "sick buildings", the children more often had eczema, dry skin, or reactions to food. The mothers' complaints about indoor air quality and climate and mucous membrane symptoms were significantly related to the type of building and presence of condensation on the windows in winter, a finding which may indicate that indoor climate factors also have some effect on the health of the children. This study reports the prevalences of symptoms until the age of 18 months. At this age, the allergic manifestations are usually nonspecific, and follow-up examinations to 4-5 years of age are needed before any definite conclusions can be drawn about the development of atopic diseases due to indoor climate factors.
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PMID:Significance of indoor environment for the development of allergic symptoms in children followed up to 18 months of age. 894 36

The addition of encapsulated enzymes (proteases and lipases) to detergents in Morocco dates from 1993. We have carried out a retrospective survey which has enabled us to evaluate the prevalence of the clinical symptoms and respiratory function problems in two groups, one exposed and the other non-exposed. This enquiry which concerns 32 exposed workers and 42 non-exposed consisted of a questionnaire (CECA OMS), a chest x-ray and some respiratory function tests. The medical study involves a question in the workplace with an evaluation of dust levels (weight of dust and enzyme activity). Fifty seven per cent of those exposed had clinical respiratory symptomatology against only 7 per cent of those who were not exposed. Rhinitis, asthma, cough, chronic bronchitis, eczema and conjunctivitis were significantly more frequent in those exposed than in the non-exposed. Respiratory function was altered in 65.5 per cent of the exposed against only 38.6 per cent of those who were not exposed. The overall lung function was of an obstructive type. The peak flow (VEMS) were more frequently reduced in those exposed (25 per cent) than in the non-exposed (7.14 per cent). These anomalies were worst at the end of a day's work. Atopy seems to be a potentiating factor. Tobacco interferes significantly in the alteration of respiratory function parameters. The enquiry in the work place revealed evidence of insufficient means of protection for the work force and elevated levels of dust which pass the mean recommended atmospheric values (500 mcg per cubic mm). On the other hand, enzymatic activity of the dust collected remained within normal limits (< 0.5 GU/m3). It is thus imperative to develop means for collective prevention (a more effective encapsulation of the enzymes, work in closed areas, ventilation with more effective dust extraction) and individuals (protective clothing and specific respiratory masks for the enzymes) to maximally reduce the risk.
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PMID:[Occupational respiratory risks in workers exposed to enzymes in detergents]. 899 75

A questionnaire which included items on wheeze, cough, eczema, hay fever, and indoor environment, including parental smoking habits, pet ownership, heating and cooking methods, home insulation, damp, mould, and years lived in their houses, was given to 1801 children, aged 12 and 14 from the Highland Region in Scotland. Of the 1537 (85%) who replied, 267 (17%) reported current wheeze, 135 (9%) cough for three months in the year, 272 (18%) eczema, and 317 (21%) hay fever. There was no consistent relationship between respiratory symptoms and indoor environment although cough was associated with damp, double glazing, and maternal smoking. The prevalence of wheeze, cough, and atopy was higher in children who had lived in more than one house during their lifetime. These results suggest that increasing mobility of families in recent years may be more important in the aetiology of asthma than exposure to any one individual allergen or pollutant.
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PMID:Wheeze, cough, atopy, and indoor environment in the Scottish Highlands. 930 78

The prevalence of asthma in school children has been reported to have increased, with wide variations between countries. To allow comparison of prevalence data, objective markers of asthma should be measured. Therefore, we assessed the prevalence of bronchial hyperresponsiveness (BHR) to hypertonic saline and its relation to asthma and allergy symptoms in 507 Austrian school children, aged 12-15 yrs in a cross-sectional, community based survey. These children were selected from 3,371 children who had answered a self-administered written questionnaire on asthma, hay fever, eczema and environmental factors. The prevalence of BHR to hypertonic saline was 14% and the majority (70%) of the children had mild BHR. The prevalence of wheeze in the last 12 months was 12% and of a diagnostic label of asthma was 6%. Fifty three per cent of the children with symptoms in the last 12 months and a diagnostic label of asthma had BHR, and 33% of those with symptoms in the last 12 months regardless of a diagnostic label of asthma showed a positive response to hypertonic saline. Atopic dermatitis, a diagnostic label of asthma, night cough apart from colds, wheeze in the past 12 months (but not "former wheeze") and male gender were significantly associated with increased response to 4.5% saline in the final logistic regression model. These results show that the prevalence of asthma symptoms in the last 12 months and the prevalence of bronchial hyperresponsiveness to hypertonic saline are twice that of a diagnosis of asthma and that asthma might be underdiagnosed in the present population. The response to hypertonic saline is most strongly associated with current asthma and allergy symptoms. A combination of a "diagnostic label of asthma" and "asthma symptoms in the last 12 months" might best reflect "current asthma" in epidemiological studies in this population.
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PMID:Prevalence of bronchial hyperresponsiveness to 4.5% saline and its relation to asthma and allergy symptoms in Austrian children. 955 38


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