Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0010200 (
cough
)
23,843
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Pet birds may be as great an allergenic problem as cats and dogs. Some of the estimated 25 to 30 million pet birds in the United States may cause such allergic symptoms as nocturnal wheezy
cough
, asthma, rhinitis,
conjunctivitis
or other manifestations during a short or long period of induction. Most of the 62,000 exotic birds imported each month are members of the psittacine or parrot family. Such birds may be particularly troublesome in that they pollute the home environment by antigenic discharges from their integument.
...
PMID:Respiratory tract allergy to household pet birds. 669 95
Clinical signs and haematological findings during the acute and convalescent phases of an infection with bovine respiratory syncytial virus (RSV) were studied under field conditions. The study was carried out in 139 cattle less than 16 months of age in 16 herds with serologically proven bovine RSV infections. Blood was collected for serological and haematological examination. Repeated clinical examinations were carried out until 35 days after appearance of disease. Signs of general disease such as reduced appetite and a body temperature of 40 degrees C or higher lasted less than three days in most cases. Signs of upper respiratory disease, such as
coughing
, nasal discharge and
conjunctivitis
were predominant and persisted in 10 to 30 per cent of the animals till the end of the observation period. Signs of lower respiratory disease such as abdominal breathing, bronchial and bronchovesicular sounds on auscultation and a high respiration rate were valuable in diagnosing the disease. These symptoms were present in about 50 per cent of the animals in the early stages of the disease. They lasted for about six days and disappeared in most animals after about 10 days. On haematological examination statistically significant blood changes were observed. A rise in zinc and iron between day 0 and day 10 and a reduction in copper content between day 10 and day 21 were found.
...
PMID:Bovine respiratory syncytial virus infections in young dairy cattle: clinical and haematological findings. 670 77
The pulmonary and nonpulmonary effects of cement dust exposure in 52 randomly selected, directly exposed cement workers and 24 maintenance workers were investigated. Compared with the nonindustrially exposed population, both subgroups had significantly (P less than 0.001) lower lung function. The lung function of the exposed subjects was probably influenced by the level of physical activity and the level of dust exposure. The more directly exposed cement packers had significantly (P less than 0.05) lower lung function than the less exposed cement loaders. There was no significant difference in the lung function of the directly exposed groups and the maintenance group, but the physically more active cement loaders showed higher lung function values than the maintenance workers. The lung function of the cement workers also decreased with the duration of employment. Cement dust produced significant (P less than 0.001) workshift depression in the lung function of the subjects. The symptoms presented by the subjects were
cough
and phlegm production, skin irritation, chest tightness,
conjunctivitis
, catarrh, stomachache, and boils. The prevalence of stomachache among the subjects becomes significant in the light of a finding by other workers of hepatic granuloma in cement workers. The measured dust level in the cement depot was 30.81 mg/m3.
...
PMID:Pulmonary function and symptoms of Nigerian workers exposed to cement dust. 671 89
Clinical manifestations, diagnostic studies and management of chlamydial pneumonia were reviewed in 115 infants and compared to those from 21 infants with interstitial pertussoid eosinophilic pneumonia. The identity of these two forms of subacute afebrile pneumonia is suggested. Chlamydial pneumonia is natally acquired, essentially occurs during the second and third month of life, and its frequency in the United States is surprisingly high. Gradual onset of respiratory tract symptoms, lack of possible infection from symptomatic persons, afebrile course and staccato
cough
represent the typical anamnesis. Presence of
conjunctivitis
and serous otitis is common. Distinctive diagnostic studies include slight eosinophilia (greater than or equal to 300 eosinophils/mm3), elevated serum immunoglobulins M and G, depressed PO2 and normal PCO2 in arterial blood under room air, and both interstitial infiltrates and hyperexpansion of the lungs on chest roentgenogram. Chlamydial cultures of nasopharyngeal secretions or tracheal aspirates, and determination of antichlamydial antibody titers in serum are indicated in establishing the etiology. Adequate management consists of antichlamydial chemotherapy and general supportive care, including chest physiotherapy and oxygen and parenteral fluids when needed.
...
PMID:Infantile chlamydial pneumonia--a review based on 115 cases. 680 74
Lyme disease, caused by a tick-transmitted spirochete, typically begins with a unique skin lesion, erythema chronicum migrans. Of 314 patients with this skin lesion, almost half developed multiple annular secondary lesions; some patients had evanescent red blotches or circles, malar or urticarial rash,
conjunctivitis
, periorbital edema, or diffuse erythema. Skin manifestations were often accompanied by malaise and fatigue, headache, fever and chills, generalized achiness, and regional lymphadenopathy. In addition, patients sometimes had evidence of meningeal irritation, mild encephalopathy, migratory musculoskeletal pain, hepatitis, generalized lymphadenopathy and splenomegaly, sore throat, nonproductive
cough
, or testicular swelling. These signs and symptoms were typically intermittent and changing during a period of several weeks. The commonest nonspecific laboratory abnormalities were a high sedimentation rate, an elevated serum IgM level, or an increased aspartate transaminase level. Early Lyme disease can be diagnosed by its dermatologic manifestations, rapidly changing system involvement, and if necessary, by serologic testing.
...
PMID:The early clinical manifestations of Lyme disease. 685 26
In October 1978, a nationwide initiative to eliminate indigenous measles from the United States by October 1, 1982, was announced. The measles elimination program has three major elements: attaining and maintaining high immunization levels, aggressive and effective surveillance, and vigorous response to cases. In 1980, immunization levels in children entering school for the first time were 96%, indicating that the necessary levels have been attained in the age group. Mechanisms are in place to assure maintenance of these levels; these rely heavily on the use of immunization requirements for school attendance in each state. Aggressive surveillance systems have been developed for each state to detect suspected measles cases as soon as possible after they occur and to investigate them within 24 hr of notification. The clinical definition of measles used is fever of greater than or equal to 101 F (38.3 C); rash of three or more days duration; and
cough
, coryza, or
conjunctivitis
. The response to outbreaks involves identifying persons in the area who are at risk of contracting measles, determining those who are possibly susceptible, and ensuring that these persons are vaccinated. In school outbreaks, susceptible students are vaccinated or excluded from school until the outbreak is over. During 1981, measles morbidity reached a record low level of only 3,032 reported cases (provisional total). Epidemic measles occurred in only a few outbreaks of limited size and duration, and endemic cases were restricted to a small number. Imported cases averaged slightly more than two per week, occasionally producing limited outbreaks, but more often resulting in no secondary spread. Transmission of measles has been interrupted in most of the United States. With continued vigorous implementation of the current strategy and with additional measures to lessen the risk of importations, it appears likely that the goal to eliminate indigenous measles transmission will be attained by October 1982.
...
PMID:Elimination of indigenous measles from the United States. 687 11
This paper presents preliminary findings about morbidity observed in a prospective epidemiological study in a village community near Khartoum during 1977-1979. A total of 293 under-five children in 310 households were followed up for two years. Each household was visited twice monthly and information of the disease pattern was collected.
Cough
, fever and diarrhoea were found to be the commonest cause of morbidity. The average incidence being 296, 292 and 217 episodes respectively per 100 children per year. Vomiting, skin disease and
conjunctivitis
occurred at a much lower rate. Measles was observed in 14% of children under one year of age. The incidence of whooping cough was low an no outbreak occurred during the two years of observation. The seasonality of various diseases, their severity and age distribution is discussed and compared over the two year period.
...
PMID:Morbidity patterns among under-five children in a rural community in Sudan. 724 43
Preliminary data from farm herds fed excessive dietary iodide and displaying signs of iodism indicated hyperglycemia, hypocholesterolemia, and a neutrophilic-lymphopenic shift in blood leukocytes. Subsequently blood, milk, and urine were analyzed from 90 cows in 10 herds fed normal (average 16 mg/cow daily) or high (average 164 mg) iodide as ethylenediamine dihydriodide for prophylactic purposes and from one herd fed iodinated casein for 3 wk. Glucose, area nitrogen, and neutrophils were higher while cholesterol and lymphocytes were lower in blood from cows fed high iodide. Milk iodide averaged .37 +/- .03 ppm from normal and 2.16 +/- .25 from herds fed high iodide. Neutrophils, glucose, protein, and globulin of serum increased while lymphocytes, cholesterol, and thyroxine decreased as iodide in milk and urine increased. Signs of iodism included lacrimation, coryza,
conjunctivitis
,
coughing
, hair loss, and exophthalmus. These findings corroborate other reports that excessive iodide alters metabolism and is toxic to immune mechanisms, suggesting that dietary iodide should be limited to nutritional requirements and prolonged prophylactic or therapeutic use should be avoided.
...
PMID:Chronic iodine toxicity in dairy cattle: blood chemistry, leukocytes, and milk iodide. 737 97
Fifteen incidents of infectious bovine rhinotracheitis (IBR) were studied in herds distributed widely throughout northern Britain. Fattening beef animals (10 outbreaks), dairy cattle (four outbreaks) and suckler beef cows (one outbreak) were affected and all bar one incident occurred in housed cattle during the winter. The first signs of illness noticed were a reduced appetite, dullness,
coughing
and oculonasal discharge. In 13 of the incidents they were observed in cattle purchased from a market within the previous four weeks. In every outbreak, affected animals developed a serous nasal discharge which became purulent in severe cases. In the early stages the nasal mucosa was congested but later yellow-brown diphtheritic plaques developed. In such animals halitosis was always detected. Soft
coughing
was frequently heard but pneumonia was rarely confirmed ante mortem.
Conjunctivitis
and ocular discharge were a major finding in 13 incidents and, in severely affected cases, conjunctival oedema was seen. The drooling of saliva was noticed in 14 incidents but congestion of the oral mucous membranes was the only abnormality found on examination of the oral cavity. Diarrhoea was a consistent feature in one outbreak. As a result of contracting this disease beef cattle failed to put on weight for a period of one to eight weeks and the milk yield of lactating dairy cattle decreased markedly. The morbidity rate was high, being more than 90 per cent in 10 incidents. The mortality rate varied considerably but 7 to 8 per cent of the animals died, or were culled, in three outbreaks. The clinical signs were most severe on intensive units with a high turnover of cattle.
...
PMID:Clinical and epidemiological features of 15 incidents of severe infectious bovine rhinotracheitis. 745 95
A subacute pneumonic disease in a young infant characterized by insidious onset and protracted course is described. The child was afebrile, tachypneic, with a staccato
cough
,
conjunctivitis
, eosinophilia and disseminated crepitations on auscultation. The chest X-ray showed extensive infiltration and hyperexpansion. Immunoglobulin fractions G and M and antibody titers against chlamydia trachomatis were elevated. These findings suggest the existence of chlamydial pneumonitis in small infants in Austria. It will only be possible to estimate the incidence of chlamydial disease when the appropriate microbiologic techniques are available.
...
PMID:[Chlamydia trachomatis infant pneumonitis (author's transl)]. 746 35
<< Previous
1
2
3
4
5
6
7
8
9
10
Next >>