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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

This is a report of the clinical analysis of 250 cases of dengue fever-like patients during the 1987-1988 epidemic in Southern Taiwan at Harn's clinic, Kaohsiung city. The results were: The peak age groups were between 20-40 years old. The ratio of male to female was 1:14. 98% patients presented with fever of mainly 3 to 6 days duration. 98% reported body pain, which included headache (82%), generalized soreness (65%), low back pain (50%). 95% patients had GI symptoms, such as anorexia (73%), nausea (60%), vomiting (45%). 97% patients complained of dizziness and weakness, and 22.4% patients had a bleeding tendency. The common bleeding sites were involving the subcutaneous (skin), gum, uterus, nasal cavity, GI tract, retina, and GU tract. The eruption rate was 78%. A majority of rashes appeared on the extremities, and then spread to the trunk. Less common symptoms were insomnia, chest tightness, urgency of urination, cough, running nose, palpitation, and shock. 45% patients were noted with hair loss. The hair loss was the latest presenting symptom, which tended to occur about two months after the recovery stage, and lasted for about one month. On physical examination, 62.6% patients had conjunctivitis, while only 1.3% had lymph node enlargement. Usually, the whole clinical course lasted for 7 to 14 days. Laboratory examination showed that leukopenia was noted from the second day and reached the lowest count on the fifth day, and recovered on 9th or 10th day. In 247 blood sera tested serologically for dengue fever, 84 were confirmed, while 157 were not confirmed yet due to patients' reluctance to accept a second blood drawing.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Clinical study on dengue fever during 1987-1988 epidemic at Kaohsiung City, southern Taiwan]. 273 68

A total of 205 infants who were hospitalized when younger than 3 months of age for pneumonitis were followed longitudinally. Of these patients, 145 (70%) had evidence of infection with one or more pathogens. The most common etiologic agents were Chlamydia trachomatis 61/193 (36%), respiratory syncytial virus 33/142 (23%), cytomegalovirus 42/203 (20%), Pneumocystis carinii 30/171 (17%), and Ureaplasma urealyticum 21/125 (16%). The initial clinical presentation was characterized by cough, rales, normal temperature, and diffuse obstructive airways disease by chest roentgenogram. Regardless of etiology, significant association occurred for cough and cytomegalovirus, apnea and Pneumocystis, and conjunctivitis and Chlamydia. Longitudinal follow-up demonstrates a mortality of 7/205 (3.4%). Morbidity was manifest as recurrent wheezing episodes in 86/187 (46%) patients, persistently abnormal chest roentgenographic findings for at least 12 months in 17/109 (15%) patients, and abnormal pulmonary functions in 15/25 (60%) patients. These abnormalities occurred irrespective of prematurity, atopy, or the initial etiologic agent associated with the pneumonitis. These data add further evidence that respiratory infections during infancy may well be predecessors of obstructive airways disease in later life.
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PMID:Infant pneumonitis associated with cytomegalovirus, Chlamydia, Pneumocystis, and Ureaplasma: follow-up. 302 7

Among 149 consecutive infants with ophthalmia neonatorum in Nairobi, Neisseria gonorrhoeae was recovered from 43%, Chlamydia trachomatis from 13%, and both microorganisms from 4%. Three of five isolates of C. trachomatis belonged to trachoma serovars. The sensitivity and specificity of a gram-stained smear for the diagnosis of gonococcal conjunctivitis were 86% and 90%, respectively. Patients with gonococcal conjunctivitis had more purulent discharge, a higher clinical severity score, and a younger age at onset of disease. Corneal epithelial edema with superficial keratitis was present in four (16%) of 25 patients with gonococcal conjunctivitis but in none of 22 other patients (P = .07). N. gonorrhoeae or C. trachomatis was isolated from the pharynx in 11 (15%) and six (23%) cases, respectively. Oropharyngeal gonococcal infection was associated with coughing (P = .007).
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PMID:Ophthalmia neonatorum in Nairobi, Kenya: the roles of Neisseria gonorrhoeae and Chlamydia trachomatis. 308 64

The clinical symptoms and signs were assessed in 20 consecutive patients developing infection with the human immunodeficiency virus (HIV). All were male homosexuals and all presented with a glandular-fever-like illness. Changes in laboratory values were compared with findings in 40 HIV negative male homosexual controls. In the 10 patients for whom date of exposure to the virus could be established the incubation period was 11-28 days (median 14). One or two days after the sudden onset of fever patients developed sore throat, lymphadenopathy, rash, lethargy, coated tongue, tonsillar hypertrophy, dry cough, headache, myalgia, conjunctivitis, vomiting, night sweats, nausea, diarrhoea, and palatal enanthema. Twelve patients had painful, shallow ulcers in the mouth or on the genitals or anus or as manifested by oesophageal symptoms; these ulcers may have been the site of entry of the virus. During the first week after the onset of symptoms mild leucopenia, thrombocytopenia, and increased numbers of banded neutrophils were detected (p less than 0.0005). The mean duration of acute illness was 12.7 days (range 5-44). All patients remained healthy during a mean follow up period of 2.5 years. Heightened awareness of the typical clinical picture in patients developing primary HIV infection will alert the physician at an early stage and so aid prompt diagnosis and help contain the epidemic spread of AIDS.
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PMID:Clinical picture of primary HIV infection presenting as a glandular-fever-like illness. 314 67

An epidemiological study of 2153 workers in 15 West Yorkshire wool textile mills was conducted to determine relations between respiratory symptoms and exposure to inspirable wool mill dust. A questionnaire designed to elicit all the common respiratory symptoms was developed and tested, and administered to all workers willing to participate (85%). It was translated and administered in Urdu for the 385 workers from Pakistan whose English was not fluent. Symptoms investigated included cough and phlegm, wheezing and chest tightness, breathlessness and its variability, rhinitis, conjunctivitis, chills, nosebleeds, and chest illnesses. Additional questions were asked, where appropriate, about the times of day, days of the week, seasons, and places that the symptoms were worse or better than normal. An environmental survey was carried out at each mill, which included 629 measurements of inspirable dust, enabling estimates to be made of the airborne concentrations of inspirable dust usually experienced by each member of the workforce under current conditions. Overall symptom prevalences were: persistent cough and phlegm, 9%; wheeze, 31%; breathlessness on walking with others on level ground, 10%; persistent rhinitis, 18%; persistent conjunctivitis, 10%; persistent chills, 2%; ten or more nosebleeds a year, 2%; and three or more chest illnesses in past three years, 5%. After allowing for the effects of age, sex, smoking habit, and ethnic group, cough and phlegm, wheeze, breathlessness, rhinitis, conjunctivitis, and nosebleeds were found to be more frequent in those exposed to higher than to lower concentrations of dust. In some experiencing high concentrations (blenders and carpet yarn backwinders) cough and phlegm, wheeze, rhinitis, and conjunctivitis were related to the years worked in such jobs. Relative risks of each symptom in relation to inspirable dust concentrations were calculated by means of a logistic regression analysis. At concentrations of 10 mg/m3, the current United Kingdom standard for nuisance dusts, the risk of cough and phlegm relative to that of an unexposed worker was 1.37, that of wheeze 1.40, breathlessness 1.48, rhinitis 1.24, and conjunctivitis 1.70. Since some of these symptoms may be associated with functional impairment of the lungs, further studies of selected workers are being carried out to estimate the functional effects of exposure to dust in wool textile mills.
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PMID:Respiratory and allergic symptoms in wool textile workers. 326 11

This report describes a case of reversible obstructive sleep apnea caused by occupational exposure to an inhaled allergen, guar gum powder. The patient, a pet food plant employee, also experienced severe cough, rhinitis, and conjunctivitis. Skin tests confirmed the specific guar allergy. Pharyngeal cross-sectional area was smaller than normal. Pulmonary function studies, histamine challenge tests, nasal air-flow resistance measurements, and nocturnal polysomnography were performed on 3 separate occasions: while the patient was working at his usual occupation, at the end of a 3-wk holiday, and after a guar dust challenge in an inhalation chamber. Pulmonary function and histamine challenge tests were consistently normal. At the time of the initial tests, nasal resistance was elevated, and nocturnal polysomnography revealed obstructive sleep apnea. After absence from work, obstructive sleep apnea resolved, and the nasal resistance returned to normal. After challenge with guar gum dust, the patient developed increased resistance to nasal air flow, and obstructive sleep apnea reappeared. This case demonstrates that allergy can cause reversible obstructive sleep apnea and that occupational exposure should be considered in the assessment of patients with this disease.
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PMID:Reversible obstructive sleep apnea caused by occupational exposure to guar gum dust. 370 5

Out of 2.513 clinical files of allergic children, we have found 200 pollen-allergic patients, which represent 7.9% of the total allergic pathology in children, in our environment. We have studied in these 200, the most important epidemiological parameters and the influence that this can cause upon the characteristics of this disease. A male predominance has been found (70%) and it has been discovered that 52% of the total were born in spring (p less than 0.0005). An hundred per cent have shown grass-pollen sensitiveness and 52% have also shown other kinds of pollen hypersensitivity. It has been found familiar allergic background in 76.5% of the cases and in 32.5% familiar allergic history of pollinosis. Unexpectedly, those who were in lack of familiar allergic history began their clinical symptoms earlier; 51.06% before 6 years of age (p less than 0.05). Other kinds of allergic manifestations were found in 51%, being respiratory symptoms the most important (35.5%), followed by the cutaneous (23.5%) and digestive ones (10.5%). Allergy to drugs was found in 10.5%. The more frequent symptoms of pollinosis were in order of importance: rhinitis (86.5%), conjunctivitis (77%), asthma (48%), spasmodic cough (27.5%) and urticaria (4%). Asthma induced by grass-pollen hypersensitivity was equally suffered by the males as by the females, and this was more frequent among the patients who had previously suffered from non-pollinic respiratory allergies.
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PMID:[Natural history of pollinosis in childhood]. 370 20

This paper describes the results of a study of live attenuated measles vaccines (one in a series of WHO-sponsored field trials) carried out in children 6-33 months old at an orphanage in Quebec City. The Enders Edmonston B vaccine alone and the same vaccine administered with gamma-globulin were compared with the Schwarz further-attenuated vaccine. The over-all seroconversion rates were found to be 96.9%, 98.1% and 98.8% respectively. Severe clinical reactions, except for high fever, were not observed in any of the groups. Rectal temperatures over 103 degrees F (39.5 degrees C) were noted in 16.2% of the children given Schwarz vaccine, in 59.2% of the children receiving the Enders Edmonston B vaccine alone and in 27.8% of the children inoculated with the Enders Edmonston B vaccine plus gamma-globulin. The high incidence of mild pharyngitis following inoculation of these vaccines was not observed in the group of children who had received vaccine plus gamma-globulin. No significant differences were noted in the frequency of other symptoms, such as cough, coryza, conjunctivitis and diarrhoea, between vaccinated and control groups.
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PMID:Studies on attenuated measles-virus vaccines in Canada. 529 4

Enteric types of adenovirus have recently been identified as a causative agent of infantile gastroenteritis. We utilized enzyme immunoassay and tissue culture techniques to evaluate prospectively the role of ET Ad in diarrhea occurring in hospitalized infants. We found that ET Ad was associated with 14 of 27 cases of diarrhea occurring during a 12-week study period in the late autumn and early winter months; ET Ad was found in the stool of only one of 72 children without diarrhea (P less than 0.001). Although adenoviruses other than ET Ad were found in the stools of two of the 27 children with diarrhea, such viruses were also found in the stools of five of 72 children without diarrhea and thus could not be statistically correlated with acute gastroenteritis. Children infected with ET Ad had diarrhea for a mean of 8.0 days, compared to a mean duration of 4.2 days for the children with gastroenteritis not associated with ET Ad. Thirteen of the 14 children with ET Ad gastroenteritis had respiratory symptoms such as cough, rhinorrhea, or wheezing, six had roentgenographic evidence of pneumonia, and three children had bilateral conjunctivitis. This study documents that ET Ad can be an important cause of acute gastrointestinal disease in hospitalized infants and young children and that gastrointestinal infections with ET Ad can be associated with a high rate of respiratory disease.
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PMID:Gastroenteritis associated with enteric type adenovirus in hospitalized infants. 628 53

Adverse reactions to measles vaccine observed in children vaccinated between September, 1981 and May, 1983 in a Socio Sanitary Local Unit of Lombardy were studied. The adverse reactions more frequently reported by the parents were cough (18%), rash (12%), fever (9%), coryza (6%) and conjunctivitis (6%). Beginning September, 1982 a case-control study was started matching each vaccine with an unvaccinated child of the same age and sex. Statistically significant differences between vaccinated and controls have been observed only for rash and fever but not for the other symptoms. During the study febrile convulsions with spontaneous recovery and without sequelae have been observed in two vaccinated children.
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PMID:Adverse reactions to measles vaccine. 646 53


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