Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0010200 (cough)
 23,843 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Reports is the case of a 21-year-old student, who received a medical examination at our Department for an abnormal chest shadow that had been detected during a periodic health examination at his university. No special subjective symptoms such as a cough and/or sputa, pyrexia, pectoralgia, and dyspnea were noted. A thyroid tumor was palpable and a 99mTc thyroid scintigram and a 201Tl thyroid tumor scintigram gave cause to suspect thyroid cancer and a metastatic lung tumor. A total thyroidectomy and a right modified neck dissection revealed a tumor (histologically, a papillary cancer), 3.5 cm in diameter, that mainly involved the right lobe. It was found that 131I-100 mCi internal irradiation was very effective for the metastatic lung tumor, and no abnormal shadow was subsequently revealed by chest X-ray. Now, 6 years later, he is alive with no manifestations of a local relapse nor any abnormal chest X-ray findings.
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PMID:[Metastatic lung tumor of a thyroid cancer origin detected by a periodic health examination--a case of a complete response]. 229 94

Progress in anesthesia, surgical techniques, and understanding of the pathophysiology of the trachea has made tracheal reconstruction a safe operative procedure. As of December 1999, 109 patients had undergone tracheal reconstruction at the author's institution. Diseases included: tumorous lesions in 83, consisting of 13 primary tracheal tumors and 70 carcinomatous invasions originating from adjacent organs such as thyroid cancer; and 26 benign stenotic lesions such as postintubation stenosis in 15, posttraumatic stenosis in 9, and congenital and tuberculous stenosis in one case each. Among the 109 patients, resection of the trachea and end-to-end anastomosis were performed in 105 patients and partial resection of the trachea with direct closure was done in 4 patients. Complications at anastomosis were seen in 5 patients, with stenosis at anastomosis in 2, suture failure in 2, and malacia in one. The most frequent lesion seen at our institution was thyroid carcinoma invading the trachea in 64 patients. The number of tracheal rings resected ranged from 1 to 11, with an average of 6. Complete resection was done in 34 of these 64 patients, and their 5- and 10-year survival rates were 79.4% and 75.6%. In 30 patients in whom resection was incomplete the 5- and 10-year survival rates were 52.8% and 35.5%, respectively. Tracheal reconstruction for another tumorous and non tumorous origins improved QOL of patients suffering from cough, sputum, hemosputum and dyspnea, and it was even life saving.
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PMID:[Tracheal reconstruction]. 1094 70

An 82-year-old woman was admitted to our hospital with cough and back pain. A chest radiograph showed a solitary nodular lesion in the right lower lung field. It was diagnosed by a transbronchial biopsy as lung metastasis of a papillary adenocarcinoma of the thyroid. However, her cervical CT and ultrasonography showed only a cyst in a right lobe of the thyroid, and its biopsy did not show evidence of malignancy. In addition, multiple bone metastasis and pituitary metastasis were revealed. We therefore diagnosed this case as systemic metastasis of papillary adenocarcinoma of the thyroid. She was given best supportive care and she died seven months later. Autopsy revealed two tiny lesions (3mm and 6mm) in the thyroid right lobe to be papillary adenocarcinoma. We report this case because occult thyroid cancer caused systemic metastasis and the chest X-ray showed lung metastasis from the thyroid cancer as a solitary nodular lesion.
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PMID:[A case of occult thyroid cancer detected as a solitary nodular lung metastasis]. 1870 May 79

Thyroidectomy is a safe procedure often performed either for benign or malignant thyroid diseases. Complication rate is low and tracheal injury associated with thyroidectomy is rarely described. The trachea may be perforated or lacerated intraoperatively; nevertheless, damage is usually recognized and directly repaired with reduced patient morbidity. We review a case of a 45-year-old male with a history of non-invasive thyroid cancer who underwent a total thyroidectomy with a tracheal necrosis and a subsequent rupture presenting 4 days following surgical operation. At home, while coughing, the patient experienced rapid swelling of neck, face and upper part of the chest. Computed tomography scan images demonstrated extensive subcutaneous emphysema and a defect in cervical trachea, confirmed also by bronchoscopy. The patient, without delay, underwent an exploration of the neck with a debridement of laceration. In view of the fact that a local infection was present, only a right pre-thyroid muscle flap was stitched on the defect. The patients recovered uneventfully.
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PMID:It sometimes happens: late tracheal rupture after total thyroidectomy. 2223 32

The patient was a 60-year-old woman who underwent chest wall resection for a metastatic tumor in the anterior portion of the right 3rd rib, from thyroid cancer. The anterior portion of the right 3rd rib and the 2nd and 3rd intercostal muscles were resected, and chest wall reconstruction was not performed. On the 5th postoperative day, the patient developed a pulmonary hernia. Radiologically, more than half of the right upper lobe and middle lobe were prolapsed from the resected chest wall. The patient complained of cough and dyspnea, and an emergency surgery was performed. Elevated intrathoracic pressure due to obesity was considered to be a serious risk factor of the lung hernia after chest wall resection without reconstruction.
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PMID:[Emergency Surgery for a Lung Hernia after Resection of a Metastatic Rib Tumor;Report of a Case]. 2721 Feb 62