Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0009952 (febrile convulsions)
 1,215 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a 7-year prospective follow-up of 104 children with enuresis in 32 cases (19 boys and 13 girls) coexistence of common migraine was found. Twenty-two children had various other seizure-like disorders, particularly tics, febrile convulsions, pavor nocturnus and fainting, and three had absence attacks. In 20 cases vasomotor disturbances and in 17 abnormal Schellong's test were found. The IQ was normal or high in all cases. Emotional disorders were observed in nearly half the cases. The water-salt test of Decourt was done in 9 cases and it was abnormal in 8 cases. At least two abnormal EEG records were obtained in 26 cases, and in 24 of them seizure activity was demonstrated in the EEG. In the period of follow-up disappearance or very marked improvement of enuresis occurred in all cases and migrainous attacks became less frequent and intense in 27 cases, while in 5 the severity of migraine increased. The author discusses the pathological mechanism of these disturbances calling attention to less good efficiency of the regulatory functions of the centrencephalic activating system and hypothalamus connected with biochemical and bioelectric immaturity.
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PMID:[Coexistence of idiopathic spontaneous nocturnal enuresis and migraine in children]. 344 4

42 children representative of Swedish urban seven-year-olds with a combination of various minor neurodevelopmental deficits in the form of so-called minimal brain dysfunction (MBD) syndromes were compared with 51 children of the same age without such problems as regards general health data from parents' interviews and questionnaires and from paediatric examinations. The findings at the physical examination revealed only few and small differences concerning minor physical anomalies that, in part, is dealt with in a separate report. Children with MBD had experienced simple febrile convulsions significantly more often than controls, and an abnormal EEG was a common finding in these cases. So-called psychosomatic complaints were not overrepresented in the MBD group, but enuresis and encopresis was somewhat more common. The parents' answers to a set of 6 questions (concerned with late speech development, late motor development, gross motor clumsiness, fine motor clumsiness, "shuffling" and difficulties to concentrate) were found to have a high discriminating capacity detecting for MBD syndromes. The possibility of a clinical application of this finding is discussed.
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PMID:Perceptual, motor and attentional deficits in seven-year-old children. Paediatric aspects. 685 75

In a series of 635 single non-malformed newborn infants with a gestational age ranging from 35 to 43 weeks we found venous haematocrit values of 60% or greater (range 60-72%) in 117 (18%); 30 neonates (4.7%) had haematocrits above 65%, and of these, 7 had values above 70%. Only 13 developed symptoms, all minor, which might be ascribed to polycythaemia, and all 117 survived. Haemodilution was not performed in any case. Ninety-eight children were followed up at the age of 2.5 years with a physical examination and a Denver Developmental Screening Test. At the age of 6 years an interval story concerning development and health was obtained from a questionnaire in 92 children; 4 children were lost to both follow-up investigations. Of the 113 children, 104 (92%) were classified as normal. The remaining children suffered from febrile convulsions (one case), nocturnal enuresis (five cases), speech defect (one case), gross motor clumsiness (two cases) and hyperkinetic behaviour (one case). None had epilepsy or cerebral palsy. The findings were minor and showed no association to haematocrit levels or possible polycythaemic symptoms in the neonatal period. Hence we do not consider preventive haemodilution to be indicated in neonatal polycythaemia with minor or no symptoms within the studied range.
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PMID:Late prognosis in untreated neonatal polycythaemia with minor or no symptoms. 713 80