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 21,692 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Neuropsychiatric side effects have been reported with various systemic betablockers. Data submitted to the National Registry of Drug-Induced Ocular Side Effects appear to indicate similar adverse reactions secondary to topical ophthalmic timolol. One hundred sixty-three of 369 central nervous system cases (44%) reported depression, psychosis, confusion, and hallucinations following topical ophthalmic timolol administration. The psychiatric community should be aware that sudden changes in mental status or onset of common psychiatric conditions, such as depression, may be due to topical ocular timolol. Withdrawal of the drug usually results in disappearance of these effects in 1 to 7 days.
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PMID:Psychiatric side effects from topical ocular timolol, a beta-adrenergic blocker. 362 10

A 43-year-old woman presented to the emergency department with acute agitation, confusion, and tonic seizures. She had a history of drug abuse, most notably beer, which constituted her major dietary intake. The patient's seizures were at first thought to be factitious in association with an acute psychosis; however, her serum sodium concentration was 110 mEq/L and urine sodium was 14 mEq/L. The patient responded to IV hypertonic saline and subsequently recovered completely. Beer potomania, the most likely etiology for this patient's hyponatremia, is a rare disorder in which dietary sodium and protein insufficiency lead to dilutional hyponatremia.
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PMID:Beer potomania: an unusual cause of symptomatic hyponatremia. 370 70

The prevalence and characteristics of psychosis were observed in a population of 134 subjects who committed suicide in St. Louis in a 1-year period. Psychosis was diagnosed if a subject had, in the period just prior (1 month or less) to his suicide, experienced any of the following: delusions; hallucinations; bizarre behavior; disorientation, confusion, or memory loss; or formal thought disorder. Using these criteria, 25 (19%) of the 134 subjects were found to be psychotic at the time of suicide.
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PMID:Psychosis and suicide. 370 38

Postpartum psychotic episodes (PPPs) occurring during the first 6 months after delivery were prospectively studied in 88 pregnant index women with a history of nonorganic psychosis and 104 pregnant controls with no such history. While no control developed a PPP, PPPs were found following 28% of the index deliveries, almost all of these 25 cases being psychiatrically hospitalized. PPPs were especially frequent among cases with total illness diagnoses of Cycloid Psychosis and Affective Illness. More than half of the 25 cases had symptom onset within 3 weeks of delivery, and these early onset cases represented predominantly affective disorders, many of whom were manic in this episode. Cases with onset after 3 weeks were predominantly schizophrenic. Confusion was part of the current episode symptomatology in about one third of the cases and was well distributed across the different diagnostic groups.
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PMID:A prospective study of postpartum psychoses in a high-risk group. 1. Clinical characteristics of the current postpartum episodes. 377 67

This study is designed to identify psychologically meaningful correlates of high and low social functioning among alcoholics and to determine if High Social Alcoholics show greater changes between intake and 1 1/2 months into treatment than Low Social Alcoholics on various psycho-diagnostic measures. High Social group membership was found to be positively associated with scores at intake on the MCMI Compulsive-Conforming Scale. Low Social group membership was positively associated with scores on the POMS Depression-Dejection and Confusion-Bewilderment Scales; and on the MCMI Avoidant, Schizotypal, Passive-Aggressive, Psychotic Thinking, Psychotic Depression, Alcohol Abuse, and Borderline Scales. Repeated measures analyses revealed that, although both groups showed significant changes on a variety of measures, the High Social group showed significantly greater decreases between intake and 1 1/2 months into treatment than the Low Social group on the Avoidant, Dysthymic, Somatoform, and Anxiety Scales of the MCMI and on the Confusion-Bewilderment, Tension-Anxiety, and Fatigue-Inertia Scales of the POMS.
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PMID:Psychological correlates and treatment outcomes for high and low social functioning alcoholics. 378 94

Deficiencies of specific vitamins produce consistent symptoms of psychiatric disorder. Thiamine deficiency, which is common in alcoholism, can produce confusion and psychotic symptoms, in addition to neurological signs. Vitamin B12 and folate deficiency may contribute symptoms of disorientation, depression or psychosis; their measurement is a part of routine dementia work-ups. Pyridoxine deficiency results in seizures, although the effects of exogenously administered pyridoxine are not clearly understood in depression and anxiety - the disorders in which it is most frequently used clinically. The use of vitamins has been most prominent in psychiatry in the treatment of schizophrenia, where large doses of nicotinic acid were initially given alone and later combined with other vitamins and minerals. Several theoretical models were described to support the use of vitamins in schizophrenia. These included: the parallels of schizophrenia to the psychiatric symptoms of pellagra; hypotheses of a defect in adrenaline metabolism; and the accumulation of psychotoxic substances which produce psychotic symptoms. Initially, positive results were reported over 30 years ago, but have not been replicated by thorough investigations. An extensive series of comprehensive placebo-controlled trials failed to show efficacy for any of the vitamin therapies tested. Although clearly less effective than antipsychotic drug treatment, vitamin therapy is not without risks - adverse effects have been reported with nicotinic acid, pyridoxine and vitamin C.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:Vitamins in psychiatry. Do they have a role? 389 44

A middle-aged man, who presented to the emergency room because of bizarre outbursts of laughter, was found to be in partial complex status epilepticus. His seizure disorder had been misdiagnosed, at various times, as a variety of "functional" psychiatric disorders. Despite proper diagnosis and aggressive treatment, management was difficult, being complicated by postictal agitation and confusion, postictal psychosis, and interictal compulsive and paranoid personality features. This case is described, and issues of diagnosis and management in partial complex epilepsy are briefly discussed. The importance of not overlooking organic and especially epileptic factors, despite the presence of prior psychiatric illness, psychologic contributors, and environmental stressors, is emphasized.
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PMID:Complex partial status epilepticus presenting as gelastic seizures: a case report. 394 17

With the introduction of lithium and increasing evidence that bipolar disorder is a biogenetic condition, changes have occurred in the diagnosis and treatment of bipolar disorder. Cross-cultural studies indicate that in the United States there is a tendency to overuse the diagnosis of schizophrenia when bipolar may be indicated. Both disorders have psychotic symptoms, rendering diagnostic confusion possible. This paper describes the characteristics of bipolar disorder, explanatory theories and treatment. A medical model of treatment is preferred. Issues of concern to social workers are addressed.
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PMID:Bipolar disorder and social work practice. 399 37

This presentation about lack of communication on contraception between staff and patients in an outpatient mental hospital consists of 7 parts: 1) an exposition of the authors' hypothesis; 2) the subject matter and method of this study, i.e., analysis of recorded staff interviews; 3) a description of the transcripts on a textual level; 4) an inventory of staff opinions classified by the key words: "contraception, abortion, mental patient, relatives, psychiatrist and responsibility;" 5) an "analysis of structures" implied by these themes; 6) "incarnations of contraception," i.e., 12 typical histories of mental patients given or denied contraception or abortion; and 7) a conclusion. The hypothesis is that contraception speaks precisely to therapists in the repetitive relationship implied constantly by the psychotic course, in terms of desire, identity, bodily organization and structure of speech. This study is based on 10 recorded conversations between a female intern and individual hospital staff members, prompted by a newspaper article about a young psychotic given oral contraceptives without her knowledge. The transcripts revealed denial of the issue, depersonalization, projection and delegation of responsibility to others. When grouped into the 6 key words, the opinions uncovered a vast somatic field, confusion couched in metonymic figures of speech, such as using the term "woman" for "mental patient," moral, genital and sexual connotations. Mental patients were depersonalized; parental roles were confused in speaking of contraception for the patients; physicians were considered judges; responsibility was denied for the patients and avoided generally. The authors' structural analysis took the form of a diagram with responsibility in the center, always preceded or followed by contraception and abortion, and by the triangle psychiatrist-relatives-patient (or mother, young person or woman). Maternity or relationships were always excluded. The 12 anecdotes included hysteria, schizophrenia, hypochondria, obsession, drug abuse, latent homosexuality, repeated pregnancies, self-induced abortions, sterilization, abortion, pills, injections and castration without the patients' consent, or with their ambivalince toward these procedures. Thus, contraception resulted in structural reversals in both patients and staff, involving the fundamental access to genitality for patients and defensive constructions by staff, which is not surprising in a cultural milieu which confuses sexuality and procreation.
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PMID:[The problem of contraception in young psychotics treated in a day care hospital]. 444 86

Physicians see violence in beaten wives, battered children, rage reactions, murder, and suicide. They should recognize that it may be a symptom of disease if it is unprovoked or bizarre, or is associated with impaired consciousness, confusion or irrationality. Violence in episodic trance-like states suggests limbic disease (temporal lobe lesions, psychomotor epilepsy, or "dyscontrol syndrome"); in association with personality change, dementia, or psychosis, it indicates cortical disease (structural, toxic, or idiopathic).
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PMID:Medical aspects of violence. 508 77


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