Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0009443 (cold)
 92,137 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Intestinal parasites are common among labourers from foreign countries and in immigrants. Some worm-infections like ascaridiasis or enterobiasis occur in children quite often even in the cold climates. In cases of ascaridiasis only a heavy infection causes clinical symptoms. The diagnosis is made through the detection of eggs in the stools, as all the other worm-infections are diagnosed from the stool-test. Piperazine-derivatives are highly effective against ascaris; another useful drug is Pyrantel-Pamoate. Toxocara canis, which affects normally only dogs, can occur occasionally in humans. Its larvae migrate in the body and cause granulomas. The main clinical symptom of threadworms (enterobiasis) is itching around the anus. This parasite can be eradicated through Pyrvinium-Pamoate. The first symptom a patient notices in cases of taeniasis are proglottides--parts of the worms--which are passed with the stools. The drug of choice against all kinds of tapeworms is Niclosamide. Hookworms are rampant in tropical countries. Heavy infections can cause severe anemias, especially in children. Bephenium-Naphthoate and Bitoscanate are effective drugs against this parasite. The whipworm (Trichuris trichura) is very common in the warm countries. It can be treated by Tiabendazole and nowadays also with Mebendazole, which is virtually atoxic. Infections with Strongyloides stercoralis are difficult to eradicate, as there are different ways of reinfection. In case an infection with strongyloides is accompanied by other serious diseases cachexia and even fatal outcome has been seen.
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PMID:[Worm-diseases]. 95 53

A Medical Research Council study was begun in England and Wales in September 1973 to determine the incidence of hepatitis B infection among persons who reported certain specified accidents with material containing hepatitis B antigen and who were given anti-hepatitis B immunoglobulin within 14 days. It was not considered justifiable to include a control group. Anti-HBAg immunoglobulin was separated by cold ethanol fractionation from plasma in which hepatitis B antibody was detected by counterimmunoelectrophoresis. The plasma pools were examined for the presence of HBAg bu immune electron-microscopy and radioimmunoassay. The aimmunoglobulin was prepared as a 5 g per 100 ml solution and the titre of anti-HBAg measured by CIEP, RPH, and RIA. The usual dose was 500 mg-intramuscularly. The study includes a year's follow-up of each participant. Serum samples usually taken at four weekly intervals for six months, then at nine months and one year are tested, by routine methods, for abnormalities of liver function and for HBAg and anti-HGAg. Specimens are stored for further tests at the end of the study. In the first year of study 110 persons were enrolled: of these, 100 participants continued to be followed up, about half of them for more than six months.
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PMID:Anti-HBAg immunoglobulin after inoculation injuries. 120 69