Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0009402 (colorectal cancer)
53,228 document(s) hit in 31,850,051 MEDLINE articles (0.05 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 3330 Mol 2992 CRC 2258 p53 2002 KRAS 1670 catenin 1225 BRAF 1197 epidermal growth factor receptor 1139 gut 961 APC 924 carcinoembryonic antigen 854 MLH1 824 EGFR 822 vascular endothelial growth factor 762 TNM 727 CEA 686 MSH2 677 AKT 629 E-cadherin 613 caspase-3 597 cytokine 548 PI3K 545 cage 540 adenomatous polyposis coli 484 Bcl-2 459 beta-catenin 434 MAPK 424 colon carcinoma 420 p21 416 ERK 412 mTOR 411 MSH6 411 hMLH1 405 COX-2 377 VEGF 364 cyclin D1 354 cyclooxygenase-2 349 hMSH2 342 PIK3CA 339 tyrosine kinase 325 DLD 322 IL-6 321 CD8 320 thymidylate synthase 320 K-ras 317 insulin 311 STAT3 304 CD44 302 histone 298 PMS2 289 tumour suppressor 288 TNF 275 MEK 274 nodal 263 UTR 256 PTEN 255 mucin 249 NRAS 249 tumor necrosis factor 239 cyclooxygenase 237 c-Myc 225 interferon 219 ERK1 216 IFN 213 PARP 212 CD133 207 Ki-67 204 DCC 203 ras 202 HER2 201 vimentin 198 CD4 197 kit 194 proliferating cell nuclear antigen 192 cancer susceptibility 192 glycoprotein 192 HNPCC 190 matrix metalloproteinase 187 lymphoid 187 p38 186 more...

Disease colorectal cancer 53228 cancer 28170 tumor 17079 colon cancer 5506 metastases 4055 carcinogenesis 3501 carcinoma 3484 tumorigenesis 2708 breast cancer 2105 adenoma 2048 adenocarcinoma 1963 liver metastases 1892 Colorectal Cancer 1873 tumor growth 1826 rectal cancer 1784 tumor progression 1720 gastric cancer 1435 polyposis 1252 lung cancer 1161 inflammatory bowel disease 1089 Dukes 1083 familial adenomatous polyposis 1045 Lynch syndrome 1015 APC 925 colitis 874 ulcerative colitis 838 primary tumor 831 melanoma 743 prostate cancer 726 dysplasia 682 obesity 659 hepatocellular carcinoma 640 pancreatic cancer 637 ovarian cancer 584 Crohn's disease 452 Colon 436 Colon 436 Colon 436 diabetes 422 endometrial cancer 387 neutropenia 376 non-small cell lung cancer 346 gastrointestinal cancer 345 liver cancer 336 Colon cancer 291 cervical cancer 283 liver cancer 283 leukemia 274 HNPCC 262 anemia 261 renal cell carcinoma 260 lymphoma 259 esophageal cancer 253 lung metastases 241 hypertension 241 esophageal cancer 239 aggressiveness 235 Rectum 227 Rectum 227 Rectum 227 Rectum 227 squamous cell carcinoma 221 tumor angiogenesis 220 carcinomatosis 211 sarcoma 192 bladder cancer 191 cardiovascular disease 188 tumor initiation 172 thrombocytopenia 171 bowel obstruction 169 head and neck cancer 156 intestinal cancer 148 irritable bowel syndrome 147 solid tumor 147 depression 147 stomatitis 146 glioma 144 glioblastoma 142 type 2 diabetes 141 cancer recurrence 135 more...

Symptom diarrhea 784 pain 356 nausea 276 vomiting 250 fatigue 223 abdominal pain 187 constipation 128 overweight 127 nausea and vomiting 121 discomfort 97 anorexia 95 discomfort 86 anesthesia 77 cachexia 56 asthenia 49 starvation 48 colic 40 dyspnea 40 headache 38 weakness 35 collapse 30 exhaustion 29 analgesia 27 Wind 26 chills 25 seizures 22 paresthesia 21 numbness 20 Ill 20 cough 19 angina 19 erythema 16 tenesmus 16 splenomegaly 16 chest pain 15 dizziness 15 dysesthesia 14 myalgia 13 abdominal discomfort 13 chronic constipation 13 bloating 12 insomnia 12 functional recovery 11 arthralgia 11 back pain 11 decreased appetite 11 hepatomegaly 11 intestinal bleeding 10 eds 9 stigma 9 acidity 9 hemoptysis 9 ataxia 8 flushing 8 pelvic pain 8 microbial colonization 8 Scratch 7 acute abdomen 7 lethargy 7 menopausal symptoms 7 agitation 7 tremor 6 anal pain 6 urinary frequency 6 DNA marker 6 dry skin 6 cancer pain 6 sleepiness 5 abdominal cramps 5 rigors 5 HSA 5 epigastric pain 5 pallor 5 hot flashes 5 hypoproteinemia 4 shortness of breath 4 Depressive symptoms 4 thinning 4 vertigo 4 oliguria 4 more...

Drug Oxaliplatin 416 CPT-11 351 Bevacizumab 310 Cetuximab 308 Irinotecan 246 ROS 132 lysine 120 IL-2 118 Monit 111 ROC 100 Panitumumab 100 Leucovorin 100 ascorbate 80 GEO 69 CSF 66 vitamin E 65 Xeloda 56 MAP 51 Bifidobacterium 50 caffeine 48 Cardiovasc 47 IFN-gamma 46 THF 35 CTC 35 CTC 35 Gefitinib 35 Paraffin 34 Dermatol 28 CAM 28 NVP 27 Indomethacin 25 Glutathione 25 ADM 25 Herceptin 25 ABC 24 uPA 23 lactose 22 Leaf 22 EPA 22 Mutagen 21 Spectrum 20 Portal 19 G-CSF 18 ADR 18 MRC 18 Adriamycin 17 NADH 16 Sorafenib 16 Taxol 16 ALA 15 Erlotinib 14 BLM 14 CCL 14 Ethanol 14 TTC 13 Bortezomib 13 Histamine 13 Imatinib 13 Fluorescein 12 VCR 12 Lipiodol 12 Docetaxel 12 Heme 12 ACT 12 citric acid 12 Pemetrexed 11 Retinoic acid 11 CDX 11 CDX 11 ETS 10 VCR 10 Activin 10 IL-1ra 10 CTX 10 Vitamin A 10 Tarceva 10 Glycyrrhiza 9 Cimetidine 9 CTX 9 TAC 9 more...

Enzyme ERK 1805 mitogen-activated protein kinase 989 APC 930 luciferase 633 caspase-3 432 focal adhesion kinase 393 protein kinase 363 thymidylate synthase 337 MEK 332 PARP 239 dihydropyrimidine dehydrogenase 172 proteasome 153 dihydropyrimidine dehydrogenase 153 reverse transcriptase 131 AMP-activated protein kinase 120 caspase-9 118 glutathione S-transferase 112 GSK 109 thymidine phosphorylase 106 DNA methyltransferase 104 alkaline phosphatase 103 caspase-8 95 peroxidase 93 urokinase-type plasminogen activator 82 protein kinase C 80 P-glycoprotein 80 AMPK 79 lactate dehydrogenase 79 ACS 79 superoxide dismutase 78 phosphatidylinositol 3-kinase 78 catalase 76 methylenetetrahydrofolate reductase 75 methylenetetrahydrofolate reductase 75 AMPK 74 topoisomerase 73 phosphoinositide 3-kinase 71 topoisomerase 70 ATPase 66 MMP 65 DNA polymerase 62 RNA polymerase 57 collagenase 55 cdc2 48 ornithine decarboxylase 48 MAP 47 aldehyde dehydrogenase 46 aldehyde dehydrogenase 43 aldehyde dehydrogenase 42 aldehyde dehydrogenase 42 aldehyde dehydrogenase 42 NQO1 40 granzyme B 38 thymidine kinase 38 UDP-glucuronosyltransferase 38 pyruvate kinase 37 N-acetyltransferase 36 prostate-specific antigen 36 calcineurin 36 glutathione peroxidase 36 PDK1 35 gamma-glutamyl transpeptidase 34 trypsin 33 transcriptase 31 RNase 30 ALDH 30 cathepsin D 30 BAT 29 cathepsin B 29 CPT 29 caspase-1 29 RNase 29 aspartate aminotransferase 29 CPT 28 CPT 28 dihydrofolate reductase 27 glyceraldehyde-3-phosphate dehydrogenase 25 carboxylesterase 25 endonuclease 24 lipoxygenase 23 more...

Compound DNA 5448 Clin 4651 Dec 3581 5-FU 1145 TNM 727 oxygen 682 MTT 600 sodium 594 calcium 551 water 476 sulfate 449 glucose 420 folinic acid 384 CPT-11 343 vitamin D 311 tyrosine 311 barium 278 TNF 275 MEK 269 iron 266 Pac 263 methionine 259 DCC 203 ASA 198 ATP 185 ethanol 178 serine 173 phosphate 171 acetate 166 lysine 163 bromide 158 SN-38 152 galactose 138 cysteine 137 DSS 135 threonine 134 Capecitabine 134 iodine 134 arginine 132 PEG 125 hydrogen 123 zinc 123 leucine 120 selenium 119 1,2-dimethylhydrazine 113 Curcumin 112 PGA 101 nitrogen 101 His 101 GSH 99 GSH 99 alanine 96 COX 96 MDA 95 PGE 93 Leucovorin 91 MMC 90 nitric oxide 90 pyrimidine 88 pyrimidine 87 butyric acid 84 ZD1694 83 Vimentin 82 FAP 82 FAP 82 ACS 79 ACS 79 PEG 75 creatinine 72 salt 72 TOF 71 Vitamin D 69 dUTP 67 glutamine 66 copper 63 Insulin 63 PGE2 63 DFS 62 formaldehyde 61 retinoic acid 59 more...

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