Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0009402 (
colorectal cancer
)
53,228
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
3330
Mol
2992
CRC
2258
p53
2002
KRAS
1670
catenin
1225
BRAF
1197
epidermal growth factor receptor
1139
gut
961
APC
924
carcinoembryonic antigen
854
MLH1
824
EGFR
822
vascular endothelial growth factor
762
TNM
727
CEA
686
MSH2
677
AKT
629
E-cadherin
613
caspase-3
597
cytokine
548
PI3K
545
cage
540
adenomatous polyposis coli
484
Bcl-2
459
beta-catenin
434
MAPK
424
colon carcinoma
420
p21
416
ERK
412
MSH6
411
mTOR
411
hMLH1
405
COX-2
377
VEGF
364
cyclin D1
354
cyclooxygenase-2
349
hMSH2
342
PIK3CA
339
tyrosine kinase
325
more...
Disease
colorectal cancer
53228
cancer
28170
tumor
17079
colon cancer
5506
metastases
4055
carcinogenesis
3501
carcinoma
3484
tumorigenesis
2708
breast cancer
2105
adenoma
2048
adenocarcinoma
1963
liver metastases
1892
Colorectal Cancer
1873
tumor growth
1826
rectal cancer
1784
tumor progression
1720
gastric cancer
1435
polyposis
1252
lung cancer
1161
inflammatory bowel disease
1089
Dukes
1083
familial adenomatous polyposis
1045
Lynch syndrome
1015
APC
925
colitis
874
ulcerative colitis
838
primary tumor
831
melanoma
743
prostate cancer
726
dysplasia
682
obesity
659
hepatocellular carcinoma
640
pancreatic cancer
637
ovarian cancer
584
Crohn's disease
452
Colon
436
Colon
436
Colon
436
diabetes
422
endometrial cancer
387
more...
Symptom
diarrhea
784
pain
356
nausea
276
vomiting
250
fatigue
223
abdominal pain
187
constipation
128
overweight
127
nausea and vomiting
121
discomfort
97
anorexia
95
discomfort
86
anesthesia
77
cachexia
56
asthenia
49
starvation
48
dyspnea
40
colic
40
headache
38
weakness
35
collapse
30
exhaustion
29
analgesia
27
Wind
26
chills
25
seizures
22
paresthesia
21
numbness
20
Ill
20
cough
19
angina
19
tenesmus
16
erythema
16
splenomegaly
16
chest pain
15
dizziness
15
dysesthesia
14
abdominal discomfort
13
chronic constipation
13
myalgia
13
more...
Drug
Oxaliplatin
416
CPT-11
351
Bevacizumab
310
Cetuximab
308
Irinotecan
246
ROS
132
lysine
120
IL-2
118
Monit
111
Panitumumab
100
Leucovorin
100
ROC
100
ascorbate
80
GEO
69
CSF
66
vitamin E
65
Xeloda
56
MAP
51
Bifidobacterium
50
caffeine
48
Cardiovasc
47
IFN-gamma
46
CTC
35
CTC
35
THF
35
Gefitinib
35
Paraffin
34
Dermatol
28
CAM
28
NVP
27
Herceptin
25
Indomethacin
25
Glutathione
25
ADM
25
ABC
24
uPA
23
Leaf
22
EPA
22
lactose
22
Mutagen
21
more...
Enzyme
ERK
1805
mitogen-activated protein kinase
989
APC
930
luciferase
633
caspase-3
432
focal adhesion kinase
393
protein kinase
363
thymidylate synthase
337
MEK
332
PARP
239
dihydropyrimidine dehydrogenase
172
dihydropyrimidine dehydrogenase
153
proteasome
153
reverse transcriptase
131
AMP-activated protein kinase
120
caspase-9
118
glutathione S-transferase
112
GSK
109
thymidine phosphorylase
106
DNA methyltransferase
104
alkaline phosphatase
103
caspase-8
95
peroxidase
93
urokinase-type plasminogen activator
82
protein kinase C
80
P-glycoprotein
80
lactate dehydrogenase
79
ACS
79
AMPK
79
superoxide dismutase
78
phosphatidylinositol 3-kinase
78
catalase
76
methylenetetrahydrofolate reductase
75
methylenetetrahydrofolate reductase
75
AMPK
74
topoisomerase
73
phosphoinositide 3-kinase
71
topoisomerase
70
ATPase
66
MMP
65
more...
Compound
DNA
5448
Clin
4651
Dec
3581
5-FU
1145
TNM
727
oxygen
682
MTT
600
sodium
594
calcium
551
water
476
sulfate
449
glucose
420
folinic acid
384
CPT-11
343
vitamin D
311
tyrosine
311
barium
278
TNF
275
MEK
269
iron
266
Pac
263
methionine
259
DCC
203
ASA
198
ATP
185
ethanol
178
serine
173
phosphate
171
acetate
166
lysine
163
bromide
158
SN-38
152
galactose
138
cysteine
137
DSS
135
iodine
134
threonine
134
Capecitabine
134
arginine
132
PEG
125
more...