Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0009402 (colorectal cancer)
53,228 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 3330
Mol 2992
CRC 2258
p53 2002
KRAS 1670
catenin 1225
BRAF 1197
epidermal growth factor receptor 1139
gut 961
APC 924
carcinoembryonic antigen 854
MLH1 824
EGFR 822
vascular endothelial growth factor 762
TNM 727
CEA 686
MSH2 677
AKT 629
E-cadherin 613
caspase-3 597
cytokine 548
PI3K 545
cage 540
adenomatous polyposis coli 484
Bcl-2 459
beta-catenin 434
MAPK 424
colon carcinoma 420
p21 416
ERK 412
MSH6 411
mTOR 411
hMLH1 405
COX-2 377
VEGF 364
cyclin D1 354
cyclooxygenase-2 349
hMSH2 342
PIK3CA 339
tyrosine kinase 325
more...
Disease
colorectal cancer 53228
cancer 28170
tumor 17079
colon cancer 5506
metastases 4055
carcinogenesis 3501
carcinoma 3484
tumorigenesis 2708
breast cancer 2105
adenoma 2048
adenocarcinoma 1963
liver metastases 1892
Colorectal Cancer 1873
tumor growth 1826
rectal cancer 1784
tumor progression 1720
gastric cancer 1435
polyposis 1252
lung cancer 1161
inflammatory bowel disease 1089
Dukes 1083
familial adenomatous polyposis 1045
Lynch syndrome 1015
APC 925
colitis 874
ulcerative colitis 838
primary tumor 831
melanoma 743
prostate cancer 726
dysplasia 682
obesity 659
hepatocellular carcinoma 640
pancreatic cancer 637
ovarian cancer 584
Crohn's disease 452
Colon 436
Colon 436
Colon 436
diabetes 422
endometrial cancer 387
more...
Symptom
diarrhea 784
pain 356
nausea 276
vomiting 250
fatigue 223
abdominal pain 187
constipation 128
overweight 127
nausea and vomiting 121
discomfort 97
anorexia 95
discomfort 86
anesthesia 77
cachexia 56
asthenia 49
starvation 48
dyspnea 40
colic 40
headache 38
weakness 35
collapse 30
exhaustion 29
analgesia 27
Wind 26
chills 25
seizures 22
paresthesia 21
numbness 20
Ill 20
cough 19
angina 19
tenesmus 16
erythema 16
splenomegaly 16
chest pain 15
dizziness 15
dysesthesia 14
abdominal discomfort 13
chronic constipation 13
myalgia 13
more...
Drug
Oxaliplatin 416
CPT-11 351
Bevacizumab 310
Cetuximab 308
Irinotecan 246
ROS 132
lysine 120
IL-2 118
Monit 111
Panitumumab 100
Leucovorin 100
ROC 100
ascorbate 80
GEO 69
CSF 66
vitamin E 65
Xeloda 56
MAP 51
Bifidobacterium 50
caffeine 48
Cardiovasc 47
IFN-gamma 46
CTC 35
CTC 35
THF 35
Gefitinib 35
Paraffin 34
Dermatol 28
CAM 28
NVP 27
Herceptin 25
Indomethacin 25
Glutathione 25
ADM 25
ABC 24
uPA 23
Leaf 22
EPA 22
lactose 22
Mutagen 21
more...
Enzyme
ERK 1805
mitogen-activated protein kinase 989
APC 930
luciferase 633
caspase-3 432
focal adhesion kinase 393
protein kinase 363
thymidylate synthase 337
MEK 332
PARP 239
dihydropyrimidine dehydrogenase 172
dihydropyrimidine dehydrogenase 153
proteasome 153
reverse transcriptase 131
AMP-activated protein kinase 120
caspase-9 118
glutathione S-transferase 112
GSK 109
thymidine phosphorylase 106
DNA methyltransferase 104
alkaline phosphatase 103
caspase-8 95
peroxidase 93
urokinase-type plasminogen activator 82
protein kinase C 80
P-glycoprotein 80
lactate dehydrogenase 79
ACS 79
AMPK 79
superoxide dismutase 78
phosphatidylinositol 3-kinase 78
catalase 76
methylenetetrahydrofolate reductase 75
methylenetetrahydrofolate reductase 75
AMPK 74
topoisomerase 73
phosphoinositide 3-kinase 71
topoisomerase 70
ATPase 66
MMP 65
more...
Compound
DNA 5448
Clin 4651
Dec 3581
5-FU 1145
TNM 727
oxygen 682
MTT 600
sodium 594
calcium 551
water 476
sulfate 449
glucose 420
folinic acid 384
CPT-11 343
vitamin D 311
tyrosine 311
barium 278
TNF 275
MEK 269
iron 266
Pac 263
methionine 259
DCC 203
ASA 198
ATP 185
ethanol 178
serine 173
phosphate 171
acetate 166
lysine 163
bromide 158
SN-38 152
galactose 138
cysteine 137
DSS 135
iodine 134
threonine 134
Capecitabine 134
arginine 132
PEG 125
more...