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Query: UMLS:C0009402 (colorectal cancer)
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The field of cardiac blood pool imaging has been reviewed. The radioisotopes and radiopharmaceuticals used for this purpose have been discussed. Data related to the radiation exposure from these agents were presented and compared with the radiation exposure of a conventional contrast angiogram. Application of cardiac blood pool imaging to the qualitative evaluation of pericardial effusions, cogenital heart disease, acquired heart disease, and cardiac shunts have been discussed. Quantitative methods for measuring cardiac output, stroke volume, left ventricle ejection fraction, left ventricle end-diastolic volume, percent mitral valve regurgitation, and Qp:Qs flow ratios in both right-to-left and left-to-right shunts were presented in detail. Where possible, correlation with contrast angiographic findings was given. Newly developed techniques of ECG gating of cardiac images were also described in detail. This description has included applications of these techniques for evaluation of regions of myocardial dyskinesis and to quantitation of left ventricle diastolic volume, ejection fraction, time between ejection onset and peak systolic flow, ejection duration, and peak circumferential fiber shortening. Once again, these were correlated with contrast angiography where possible. It is concluded that cardiac blood pool imaging is a useful procedure capable of yielding good qualitative and quantitative results in a wide variety of clinical cardiac diseases and that these results compare favorably with those obtained by contrast angiography. Although there are limitations in the present techniques, solutions to at least some of these limitations are possible. Because of its simplicity, safety, and low cost relative to cardiac catheterization, more widespread use of these procedures is urged.
CRC Crit Rev Diagn Imaging 1979
PMID:Cardiac blood pool imaging: a review. 38 2

An 80-year-old Japanese man had a fall presented with a 3-week history of right lumbago exacerbated by body movement as well as a 1-week history of anomalous behavior and appetite loss. He visited our hospital complaining of difficulty in standing up. He had a history of mitral prolapse due to an unknown rupture of the chordae tendineae 3 years earlier, which resulted in moderate mitral valve regurgitation and atrial fibrillation. Upon visiting the hospital, he had petechial hemorrhage and jaundice of the conjunctiva, a systolic murmur (Levine II/VI) at the apex and 4th interspace of the left sternal border, and a positive right straight leg raising test result. Moderate bilirubinemia and disseminated intravascular coagulation which were considered to have been produced secondarily were observed. Infective endocarditis was suspected, and 3 sets of blood culture were extracted. The patient was admitted on the same day. Blood cultures were positive for Streptococcus gallolyticus subsp. gallolyticus (6/6) on the following day. Transesophagela echocardiography was carried out on the same day, and vegetation with a diameter of 4mm was observed in the anterior mitral leaflet; the patient was subsequently diagnosed as having infective endocarditis. Colonic endoscopy was performed after hospitalization. Twelve colonic adenomata were found, and endoscopic mucosal resection was performed on one polyp. The bacterium found in the culture was classified as Streptococcus bovis type I, which causes infective endocarditis and bacteremia. Furthermore, this bacteria is a relatively rare causative organism of infective endocarditis. Tolerance to macrolide and tetracycline are reported in the literature. Moreover, the cell wall of this bacterium may have low pathogenicity as well as cause chronic inflammation in the large intestine mucous membrane, colonic polyps, and colorectal cancer. Several colonic adenomata and a partial shift to a malignant pathology were observed in this case. When this bacterium is detected, searching for a pathological change in the large intestine is believed to be indispensable.
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PMID:[A case of Streptococcus gallolyticus subsp. gallolyticus infective endocarditis with colon adenoma]. 2519 83