Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0009319 (colitis)
19,384 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
gut 1746
cytokine 1522
Sep 1328
myeloperoxidase 1126
TNF 1043
IL-10 917
IL-6 880
CD4 747
tumor necrosis factor 693
DSS 582
Mol 572
IL-17 510
inducible nitric oxide synthase 401
lipopolysaccharide 395
IFN 379
lymphoid 335
IBD 334
collagen 302
LPS 266
interferon 264
TNF-alpha 260
IL-4 251
IFN-gamma 242
p65 230
chemokine 228
STAT3 216
TLR4 213
cyclooxygenase-2 212
COX-2 210
mucin 200
IL-8 193
CD8 181
IL-23 174
interleukin-6 173
CD25 166
She 166
IgA 158
interleukin-10 154
IL-2 154
MAPK 148
ASA 147
IL-1 145
superoxide dismutase 142
p38 140
nitric oxide synthase 127
p53 123
IL-22 121
catenin 119
occludin 118
CD11b 115
IL-18 115
Cytokine 112
caspase-3 111
type II collagen 111
tumor necrosis factor alpha 110
NLRP3 109
GSH 109
cyclooxygenase 103
interferon-gamma 103
catalase 102
IL-13 100
ERK 96
TLR2 88
TGF-beta 88
thymus 88
CD11c 86
CTLA-4 86
mTOR 80
endoplasmic reticulum 79
ZO-1 77
TCR 77
MyD88 76
ATP 75
E-cadherin 74
substance P 74
PI3K 73
Myeloperoxidase 72
C-reactive protein 71
p40 71
granulocyte 69
more...
Disease
colitis 19384
inflammatory bowel disease 4575
ulcerative colitis 3438
Colitis 3352
Crohn's disease 2301
cancer 1723
tumor 1008
colorectal cancer 874
colon cancer 602
DSS 582
DSS 582
irritable bowel syndrome 493
carcinogenesis 439
tumorigenesis 408
hemolytic uremic syndrome 391
Shiga 387
cytomegalovirus 372
dysplasia 370
carcinoma 353
arthritis 257
pneumonia 257
pseudomembranous colitis 253
enteritis 245
Colon 244
Colon 242
Colon 242
hepatitis 241
sepsis 219
enteropathy 218
adenocarcinoma 213
enterocolitis 200
ileitis 200
sepsis 197
infectious diseases 196
gastritis 190
ischemic colitis 183
proctitis 179
rheumatoid arthritis 175
celiac disease 169
megacolon 160
diabetes 157
anemia 153
Crohn's colitis 151
immunodeficiency 148
peritonitis 144
ischemia 142
Infection 140
melanoma 135
AIDS 130
asthma 126
diverticular disease 124
infectious colitis 121
primary sclerosing cholangitis 113
adenoma 111
GSH 109
autoimmune disease 109
SCID 107
diverticulitis 105
graft-versus-host disease 104
amebiasis 104
tumor growth 103
lymphoma 103
HIV 101
esophagitis 99
multiple sclerosis 98
Collagenous colitis 98
eosinophilia 97
Microscopic colitis 96
pancreatitis 95
tumor progression 95
Shigella 95
vasculitis 93
gastroenteritis 92
Clostridium difficile infection 90
malabsorption 87
obesity 87
Rectum 85
Rectum 85
Rectum 85
Rectum 85
more...
Symptom
diarrhea 2641
abdominal pain 557
pain 231
vomiting 138
constipation 94
nausea 78
anorexia 66
colic 61
fatigue 60
erythema 51
splenomegaly 42
anesthesia 38
seizures 31
headache 31
intestinal bleeding 28
tenesmus 27
discomfort 27
acute abdomen 27
dyspnea 26
discomfort 26
arthralgia 26
acute abdominal pain 21
weakness 21
abdominal cramps 20
cough 20
abdominal discomfort 18
Ill 18
lethargy 18
epigastric pain 17
chills 16
analgesia 16
hypoproteinemia 16
respiratory distress 15
collapse 15
cachexia 14
chronic constipation 12
starvation 12
hepatomegaly 12
spasm 11
bloating 11
nausea and vomiting 11
hypothermia 10
pelvic pain 10
fever of unknown origin 10
Wind 10
oliguria 9
Gastrointestinal symptoms 8
decreased appetite 8
back pain 8
myalgia 8
Visceral pain 8
sleepiness 7
flushing 7
pallor 7
hepatosplenomegaly 7
thinning 6
dizziness 6
shortness of breath 6
low back pain 6
ataxia 6
hypotonia 6
emaciation 6
blurred vision 6
chest pain 6
exhaustion 5
dysarthria 5
rectal pain 5
acute stress 5
acidity 5
insomnia 5
dry skin 5
hunger 5
right upper quadrant pain 4
urinary frequency 4
muscle cramps 4
angina 4
functional recovery 4
Watery diarrhea 4
tremor 4
syncope 4
more...
Drug
IFN-gamma 234
IL-2 155
Bifidobacterium 134
ampicillin 60
CSF 60
Ipilimumab 49
Dextran sulfate sodium 48
lysine 47
Infliximab 47
Infliximab 47
Dermatol 46
ROS 43
Budesonide 32
Mesalazine 29
Prednisolone 24
G-CSF 23
lactose 18
MAP 16
IL-11 14
ascorbate 14
Dasatinib 13
vitamin E 12
NADH 12
Indomethacin 11
Tacrolimus 11
Histamine 10
Sulphasalazine 10
Retinoic acid 10
Leaf 10
Asthma 9
EPA 9
Heme 9
Glucagon 9
Ganciclovir 8
niacin 8
Gel 8
CCL 8
Aloe 8
Rifaximin 8
p75 8
CPT-11 7
IFN-beta 7
Nitric Oxide 7
Mirtazapine 7
ALA 7
IL-1ra 7
CTX 7
Rosiglitazone 7
Prednisone 7
Growth hormone 6
Paraffin 6
Copaxone 6
ICI 6
Cardiovasc 6
Adalimumab 6
Growth hormone 6
citric acid 6
Epigallocatechin 5
Rebamipide 5
Rutin 5
Monit 5
TAK 5
Kayexalate 5
Glutathione 5
Gastro 4
Rituximab 4
Imodium 4
CTX 4
CTT 4
Glycyrrhiza 4
AZT 4
Alliance 4
Aminoguanidine 4
Anakinra 4
DPA 4
CED 4
Portal 4
PFA 4
Angiotensin II 4
CTX 4
more...
Enzyme
peroxidase 1152
mitogen-activated protein kinase 325
superoxide dismutase 184
ERK 147
catalase 116
caspase-3 94
caspase-1 86
NO synthase 80
focal adhesion kinase 74
luciferase 64
alkaline phosphatase 63
protein kinase 62
APC 50
glutathione peroxidase 45
PARP 43
AMP-activated protein kinase 42
IKK 39
NADPH oxidase 38
alanine aminotransferase 37
MIP 37
lactate dehydrogenase 36
NADPH oxidase 35
NOS 34
trypsin 33
protein kinase C 33
MEK 32
reverse transcriptase 31
proteasome 29
arginase 27
lysozyme 27
AMPK 26
AMPK 26
calcineurin 25
aspartate aminotransferase 22
ACS 22
phospholipase A2 22
lipoxygenase 22
thrombin 21
myosin light chain kinase 21
caspase-8 20
phosphatidylinositol 3-kinase 17
heme oxygenase 17
P-glycoprotein 17
glutathione S-transferase 16
phosphodiesterase 16
collagenase 15
tryptase 15
MAP 15
NQO1 14
lipase 14
GSK 14
neutrophil elastase 14
xanthine oxidase 14
ATPase 12
prolyl hydroxylase 11
dipeptidyl peptidase IV 11
caspase-9 11
elastase 11
guanylate cyclase 11
thromboplastin 10
RNA polymerase 10
phospholipase C 10
renin 10
beta-glucuronidase 10
phosphoinositide 3-kinase 10
granzyme B 10
adenylate cyclase 10
MMP-3 10
glutamate dehydrogenase 9
glutamate dehydrogenase 9
caspase-11 9
urease 9
indoleamine 2,3-dioxygenase 9
caspase-11 9
glutamate dehydrogenase 9
diamine oxidase 8
transglutaminase 8
MMP 8
Thy1 8
chitinase 8
more...
Compound
sodium 3278
sulfate 2761
Dec 1345
Clin 1252
TNF 1043
water 940
DSS 591
DNA 533
oxygen 346
nitric oxide 323
acetic acid 321
ethanol 257
ASA 159
barium 158
phosphate 130
calcium 128
acetate 124
GSH 111
GSH 111
glucose 104
iron 98
arginine 93
Dextran 80
PGE2 80
salt 79
ATP 76
tyrosine 74
PGE 70
hydrogen 66
vitamin D 66
His 65
lysine 59
nitrogen 58
galactose 56
retinoic acid 56
zinc 55
creatinine 53
nitrate 52
THP 52
THP 51
butyric acid 50
tryptophan 48
Sulfasalazine 48
leucine 46
cysteine 46
tryptophan 45
serine 45
tryptophan 44
tryptophan 44
potassium 44
5-HT 42
glutamine 42
Vancomycin 42
Sodium 40
NIDA 39
PEG 39
sulfuric acid 38
alanine 37
Curcumin 37
MDA 34
TNB 33
Azathioprine 32
CO2 32
Phe 31
Cyclosporine 30
selenium 30
NAD 29
urea 28
cAMP 28
methionine 28
Mesalamine 27
nicotinamide 27
salicylic acid 26
H2S 26
benzene 26
H2O2 26
Dexamethasone 25
EDTA 25
EDTA 25
threonine 25
more...