Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0009319 (
colitis
)
19,384
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
gut
1746
cytokine
1522
Sep
1328
myeloperoxidase
1126
TNF
1043
IL-10
917
IL-6
880
CD4
747
tumor necrosis factor
693
DSS
582
Mol
572
IL-17
510
inducible nitric oxide synthase
401
lipopolysaccharide
395
IFN
379
lymphoid
335
IBD
334
collagen
302
LPS
266
interferon
264
TNF-alpha
260
IL-4
251
IFN-gamma
242
p65
230
chemokine
228
STAT3
216
TLR4
213
cyclooxygenase-2
212
COX-2
210
mucin
200
IL-8
193
CD8
181
IL-23
174
interleukin-6
173
CD25
166
She
166
IgA
158
interleukin-10
154
IL-2
154
MAPK
148
ASA
147
IL-1
145
superoxide dismutase
142
p38
140
nitric oxide synthase
127
p53
123
IL-22
121
catenin
119
occludin
118
CD11b
115
IL-18
115
Cytokine
112
caspase-3
111
type II collagen
111
tumor necrosis factor alpha
110
NLRP3
109
GSH
109
cyclooxygenase
103
interferon-gamma
103
catalase
102
IL-13
100
ERK
96
TLR2
88
TGF-beta
88
thymus
88
CD11c
86
CTLA-4
86
mTOR
80
endoplasmic reticulum
79
ZO-1
77
TCR
77
MyD88
76
ATP
75
E-cadherin
74
substance P
74
PI3K
73
Myeloperoxidase
72
C-reactive protein
71
p40
71
granulocyte
69
more...
Disease
colitis
19384
inflammatory bowel disease
4575
ulcerative colitis
3438
Colitis
3352
Crohn's disease
2301
cancer
1723
tumor
1008
colorectal cancer
874
colon cancer
602
DSS
582
DSS
582
irritable bowel syndrome
493
carcinogenesis
439
tumorigenesis
408
hemolytic uremic syndrome
391
Shiga
387
cytomegalovirus
372
dysplasia
370
carcinoma
353
arthritis
257
pneumonia
257
pseudomembranous colitis
253
enteritis
245
Colon
244
Colon
242
Colon
242
hepatitis
241
sepsis
219
enteropathy
218
adenocarcinoma
213
enterocolitis
200
ileitis
200
sepsis
197
infectious diseases
196
gastritis
190
ischemic colitis
183
proctitis
179
rheumatoid arthritis
175
celiac disease
169
megacolon
160
diabetes
157
anemia
153
Crohn's colitis
151
immunodeficiency
148
peritonitis
144
ischemia
142
Infection
140
melanoma
135
AIDS
130
asthma
126
diverticular disease
124
infectious colitis
121
primary sclerosing cholangitis
113
adenoma
111
GSH
109
autoimmune disease
109
SCID
107
diverticulitis
105
graft-versus-host disease
104
amebiasis
104
tumor growth
103
lymphoma
103
HIV
101
esophagitis
99
multiple sclerosis
98
Collagenous colitis
98
eosinophilia
97
Microscopic colitis
96
pancreatitis
95
tumor progression
95
Shigella
95
vasculitis
93
gastroenteritis
92
Clostridium difficile infection
90
malabsorption
87
obesity
87
Rectum
85
Rectum
85
Rectum
85
Rectum
85
more...
Symptom
diarrhea
2641
abdominal pain
557
pain
231
vomiting
138
constipation
94
nausea
78
anorexia
66
colic
61
fatigue
60
erythema
51
splenomegaly
42
anesthesia
38
seizures
31
headache
31
intestinal bleeding
28
tenesmus
27
discomfort
27
acute abdomen
27
dyspnea
26
discomfort
26
arthralgia
26
acute abdominal pain
21
weakness
21
abdominal cramps
20
cough
20
abdominal discomfort
18
Ill
18
lethargy
18
epigastric pain
17
chills
16
analgesia
16
hypoproteinemia
16
respiratory distress
15
collapse
15
cachexia
14
chronic constipation
12
starvation
12
hepatomegaly
12
spasm
11
bloating
11
nausea and vomiting
11
hypothermia
10
pelvic pain
10
fever of unknown origin
10
Wind
10
oliguria
9
Gastrointestinal symptoms
8
decreased appetite
8
back pain
8
myalgia
8
Visceral pain
8
sleepiness
7
flushing
7
pallor
7
hepatosplenomegaly
7
thinning
6
dizziness
6
shortness of breath
6
low back pain
6
ataxia
6
hypotonia
6
emaciation
6
blurred vision
6
chest pain
6
exhaustion
5
dysarthria
5
rectal pain
5
acute stress
5
acidity
5
insomnia
5
dry skin
5
hunger
5
right upper quadrant pain
4
urinary frequency
4
muscle cramps
4
angina
4
functional recovery
4
Watery diarrhea
4
tremor
4
syncope
4
more...
Drug
IFN-gamma
234
IL-2
155
Bifidobacterium
134
ampicillin
60
CSF
60
Ipilimumab
49
Dextran sulfate sodium
48
lysine
47
Infliximab
47
Infliximab
47
Dermatol
46
ROS
43
Budesonide
32
Mesalazine
29
Prednisolone
24
G-CSF
23
lactose
18
MAP
16
IL-11
14
ascorbate
14
Dasatinib
13
vitamin E
12
NADH
12
Indomethacin
11
Tacrolimus
11
Histamine
10
Sulphasalazine
10
Retinoic acid
10
Leaf
10
Asthma
9
EPA
9
Heme
9
Glucagon
9
Ganciclovir
8
niacin
8
Gel
8
CCL
8
Aloe
8
Rifaximin
8
p75
8
CPT-11
7
IFN-beta
7
Nitric Oxide
7
Mirtazapine
7
ALA
7
IL-1ra
7
CTX
7
Rosiglitazone
7
Prednisone
7
Growth hormone
6
Paraffin
6
Copaxone
6
ICI
6
Cardiovasc
6
Adalimumab
6
Growth hormone
6
citric acid
6
Epigallocatechin
5
Rebamipide
5
Rutin
5
Monit
5
TAK
5
Kayexalate
5
Glutathione
5
Gastro
4
Rituximab
4
Imodium
4
CTX
4
CTT
4
Glycyrrhiza
4
AZT
4
Alliance
4
Aminoguanidine
4
Anakinra
4
DPA
4
CED
4
Portal
4
PFA
4
Angiotensin II
4
CTX
4
more...
Enzyme
peroxidase
1152
mitogen-activated protein kinase
325
superoxide dismutase
184
ERK
147
catalase
116
caspase-3
94
caspase-1
86
NO synthase
80
focal adhesion kinase
74
luciferase
64
alkaline phosphatase
63
protein kinase
62
APC
50
glutathione peroxidase
45
PARP
43
AMP-activated protein kinase
42
IKK
39
NADPH oxidase
38
alanine aminotransferase
37
MIP
37
lactate dehydrogenase
36
NADPH oxidase
35
NOS
34
trypsin
33
protein kinase C
33
MEK
32
reverse transcriptase
31
proteasome
29
arginase
27
lysozyme
27
AMPK
26
AMPK
26
calcineurin
25
aspartate aminotransferase
22
ACS
22
phospholipase A2
22
lipoxygenase
22
thrombin
21
myosin light chain kinase
21
caspase-8
20
phosphatidylinositol 3-kinase
17
heme oxygenase
17
P-glycoprotein
17
glutathione S-transferase
16
phosphodiesterase
16
collagenase
15
tryptase
15
MAP
15
NQO1
14
lipase
14
GSK
14
neutrophil elastase
14
xanthine oxidase
14
ATPase
12
prolyl hydroxylase
11
dipeptidyl peptidase IV
11
caspase-9
11
elastase
11
guanylate cyclase
11
thromboplastin
10
RNA polymerase
10
phospholipase C
10
renin
10
beta-glucuronidase
10
phosphoinositide 3-kinase
10
granzyme B
10
adenylate cyclase
10
MMP-3
10
glutamate dehydrogenase
9
glutamate dehydrogenase
9
caspase-11
9
urease
9
indoleamine 2,3-dioxygenase
9
caspase-11
9
glutamate dehydrogenase
9
diamine oxidase
8
transglutaminase
8
MMP
8
Thy1
8
chitinase
8
more...
Compound
sodium
3278
sulfate
2761
Dec
1345
Clin
1252
TNF
1043
water
940
DSS
591
DNA
533
oxygen
346
nitric oxide
323
acetic acid
321
ethanol
257
ASA
159
barium
158
phosphate
130
calcium
128
acetate
124
GSH
111
GSH
111
glucose
104
iron
98
arginine
93
Dextran
80
PGE2
80
salt
79
ATP
76
tyrosine
74
PGE
70
hydrogen
66
vitamin D
66
His
65
lysine
59
nitrogen
58
galactose
56
retinoic acid
56
zinc
55
creatinine
53
nitrate
52
THP
52
THP
51
butyric acid
50
tryptophan
48
Sulfasalazine
48
leucine
46
cysteine
46
tryptophan
45
serine
45
tryptophan
44
tryptophan
44
potassium
44
5-HT
42
glutamine
42
Vancomycin
42
Sodium
40
NIDA
39
PEG
39
sulfuric acid
38
alanine
37
Curcumin
37
MDA
34
TNB
33
Azathioprine
32
CO2
32
Phe
31
Cyclosporine
30
selenium
30
NAD
29
urea
28
cAMP
28
methionine
28
Mesalamine
27
nicotinamide
27
salicylic acid
26
H2S
26
benzene
26
H2O2
26
Dexamethasone
25
EDTA
25
EDTA
25
threonine
25
more...