Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0009319 (colitis)
 19,384 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
gut 1746
cytokine 1522
Sep 1328
myeloperoxidase 1126
TNF 1043
IL-10 917
IL-6 880
CD4 747
tumor necrosis factor 693
DSS 582
Mol 572
IL-17 510
inducible nitric oxide synthase 401
lipopolysaccharide 395
IFN 379
lymphoid 335
IBD 334
collagen 302
LPS 266
interferon 264
TNF-alpha 260
IL-4 251
IFN-gamma 242
p65 230
chemokine 228
STAT3 216
TLR4 213
cyclooxygenase-2 212
COX-2 210
mucin 200
IL-8 193
CD8 181
IL-23 174
interleukin-6 173
CD25 166
She 166
IgA 158
IL-2 154
interleukin-10 154
MAPK 148
ASA 147
IL-1 145
superoxide dismutase 142
p38 140
nitric oxide synthase 127
p53 123
IL-22 121
catenin 119
occludin 118
IL-18 115
CD11b 115
Cytokine 112
type II collagen 111
caspase-3 111
tumor necrosis factor alpha 110
NLRP3 109
GSH 109
cyclooxygenase 103
interferon-gamma 103
catalase 102
IL-13 100
ERK 96
thymus 88
TLR2 88
TGF-beta 88
CD11c 86
CTLA-4 86
mTOR 80
endoplasmic reticulum 79
TCR 77
ZO-1 77
MyD88 76
ATP 75
E-cadherin 74
substance P 74
PI3K 73
Myeloperoxidase 72
C-reactive protein 71
p40 71
IL-5 69
granulocyte 69
CXCL1 68
ERK1 68
ICAM-1 66
Bcl-2 66
T-bet 66
mast cell 65
JNK 64
CD103 63
MCP-1 63
alkaline phosphatase 63
signal transducer and activator of transcription 3 61
AKT 61
histone 59
claudin-1 58
IL10 56
PD-1 56
vascular endothelial growth factor 56
IgE 56
CD40 54
albumin 53
NOD 52
SOD 52
adhesion molecule 52
Nrf2 52
serum albumin 51
THP 51
NOD2 51
glycoprotein 49
T cell receptor 49
erythroid 48
colon carcinoma 47
insulin 47
interferon gamma 47
CD44 46
HLA-B27 46
heme oxygenase-1 46
glutathione peroxidase 45
reserved 45
CCL2 45
cyclooxygenase 2 45
CXCL10 45
STAT 45
Hermansky-Pudlak syndrome 44
MRI 44
aryl hydrocarbon receptor 43
hemoglobin 43
IL-33 43
mitogen-activated protein 43
ROS 43
HLA 42
STAT1 42
peroxisome proliferator-activated receptor 41
lectin 41
vascular cell adhesion molecule-1 41
AP-1 41
MAdCAM-1 41
PD-L1 40
MHC 40
MUC2 40
proton pump 39
Tumor necrosis factor 39
APC 39
P-selectin 38
CD28 38
GM-CSF 38
cage 38
chemokine receptor 38
matrix metalloproteinase 38
intercellular adhesion molecule-1 38
Ki-67 38
interleukin-2 37
DAI 37
MIP 37
CD62L 36
PBS 36
interleukin 6 35
proliferating cell nuclear antigen 35
TNF receptor 35
c-Jun 35
more...
Disease
colitis 19384
inflammatory bowel disease 4575
ulcerative colitis 3438
Colitis 3352
Crohn's disease 2301
cancer 1723
tumor 1008
colorectal cancer 874
colon cancer 602
DSS 582
DSS 582
irritable bowel syndrome 493
carcinogenesis 439
tumorigenesis 408
hemolytic uremic syndrome 391
Shiga 387
cytomegalovirus 372
dysplasia 370
carcinoma 353
pneumonia 257
arthritis 257
pseudomembranous colitis 253
enteritis 245
Colon 244
Colon 242
Colon 242
hepatitis 241
sepsis 219
enteropathy 218
adenocarcinoma 213
enterocolitis 200
ileitis 200
sepsis 197
infectious diseases 196
gastritis 190
ischemic colitis 183
proctitis 179
rheumatoid arthritis 175
celiac disease 169
megacolon 160
diabetes 157
anemia 153
Crohn's colitis 151
immunodeficiency 148
peritonitis 144
ischemia 142
Infection 140
melanoma 135
AIDS 130
asthma 126
diverticular disease 124
infectious colitis 121
primary sclerosing cholangitis 113
adenoma 111
autoimmune disease 109
GSH 109
SCID 107
diverticulitis 105
graft-versus-host disease 104
amebiasis 104
tumor growth 103
lymphoma 103
HIV 101
esophagitis 99
multiple sclerosis 98
Collagenous colitis 98
eosinophilia 97
Microscopic colitis 96
pancreatitis 95
tumor progression 95
Shigella 95
vasculitis 93
gastroenteritis 92
Clostridium difficile infection 90
obesity 87
malabsorption 87
Rectum 85
Rectum 85
Rectum 85
Rectum 85
tuberculosis 84
CMV colitis 84
depression 84
amebic colitis 84
rash 83
bowel obstruction 83
encephalomyelitis 81
thrombocytopenia 80
metastatic melanoma 79
dysentery 78
renal failure 78
gastrointestinal disease 78
systemic lupus erythematosus 76
ileocolitis 71
polyposis 70
malnutrition 69
psoriasis 68
salmonellosis 67
Yersinia 65
neutropenia 64
cholangitis 64
Inflammatory Bowel Disease 64
bacterial infection 64
chronic disease 63
wasting 62
Klebsiella 61
dehydration 61
appendicitis 60
Clostridium difficile colitis 60
dermatitis 59
acute renal failure 56
liver abscess 55
liver disease 53
cirrhosis 52
NOD 52
Mycobacterium 51
ileus 51
hypertension 51
encephalitis 51
familial adenomatous polyposis 50
virus infection 50
proctocolitis 49
pulmonary fibrosis 48
immunopathology 48
Hermansky-Pudlak syndrome 48
leukemia 48
eosinophilic gastroenteritis 47
cholera 47
metastases 47
atherosclerosis 47
hemolytic anemia 47
chronic granulomatous disease 46
HLA-B27 46
necrotizing enterocolitis 45
lymphadenopathy 45
bacteremia 45
thyroiditis 44
nephritis 44
acute diarrhea 43
worms 42
myocarditis 41
lymphocytosis 41
pruritus 41
APC 40
rectal prolapse 38
proctosigmoiditis 38
lung cancer 37
stroke 37
duodenitis 37
MIP 37
thrombocytopenic purpura 37
food allergy 36
Chronic colitis 36
sprue 36
renal disease 35
incontinence 35
lupus 34
osteoporosis 34
type 1 diabetes 34
cryptitis 34
more...
Symptom
diarrhea 2641
abdominal pain 557
pain 231
vomiting 138
constipation 94
nausea 78
anorexia 66
colic 61
fatigue 60
erythema 51
splenomegaly 42
anesthesia 38
headache 31
seizures 31
intestinal bleeding 28
acute abdomen 27
discomfort 27
tenesmus 27
arthralgia 26
discomfort 26
dyspnea 26
acute abdominal pain 21
weakness 21
abdominal cramps 20
cough 20
abdominal discomfort 18
lethargy 18
Ill 18
epigastric pain 17
analgesia 16
chills 16
hypoproteinemia 16
respiratory distress 15
collapse 15
cachexia 14
chronic constipation 12
hepatomegaly 12
starvation 12
nausea and vomiting 11
bloating 11
spasm 11
hypothermia 10
fever of unknown origin 10
Wind 10
pelvic pain 10
oliguria 9
Gastrointestinal symptoms 8
myalgia 8
decreased appetite 8
back pain 8
Visceral pain 8
sleepiness 7
hepatosplenomegaly 7
flushing 7
pallor 7
shortness of breath 6
hypotonia 6
low back pain 6
emaciation 6
ataxia 6
thinning 6
dizziness 6
chest pain 6
blurred vision 6
dysarthria 5
acute stress 5
dry skin 5
rectal pain 5
insomnia 5
exhaustion 5
acidity 5
hunger 5
urinary frequency 4
functional recovery 4
right upper quadrant pain 4
muscle cramps 4
angina 4
Watery diarrhea 4
syncope 4
tremor 4
non-productive cough 3
microbial colonization 3
agitation 3
stigma 3
iliac fossa pain 3
right lower quadrant pain 3
generalized abdominal pain 3
knee pain 3
stomach pain 3
sore throat 3
hemiplegia 3
hemoptysis 3
anal pain 3
vertigo 3
asthenia 3
infant diarrhea 3
pleuritic chest pain 2
distraction 2
photophobia 2
lassitude 2
abdominal fullness 2
incoordination 2
hopelessness 2
generalized rash 2
spasticity 2
myoclonus 2
enuresis 2
night sweats 2
ophthalmoplegia 2
dysuria 2
cerebellar ataxia 2
flank pain 2
despair 2
paresthesia 2
bladder pain 2
polyuria 2
loss of balance 2
Severe diarrhea 2
heartburn 2
regurgitation 2
neck pain 2
skin irritation 2
chronic cough 2
tachypnea 2
cyanosis 2
tinnitus 2
left lower quadrant pain 2
dyschezia 2
syncopal episodes 1
Floppy 1
wheezing 1
cancer pain 1
inanition 1
Sedation 1
catatonia 1
Soft stools 1
apathy 1
Joint hypermobility 1
meningism 1
clubbing 1
skin damage 1
prostration 1
thigh pain 1
CSR 1
leg edema 1
breakthrough pain 1
HSA 1
labored breathing 1
Regurgitation 1
otalgia 1
consciousness disturbance 1
chorea 1
nasal congestion 1
dysorexia 1
Spastic 1
epigastric distress 1
overweight 1
fasciculation 1
neuralgia 1
numbness 1
more...
Drug
IFN-gamma 234
IL-2 155
Bifidobacterium 134
CSF 60
ampicillin 60
Ipilimumab 49
Dextran sulfate sodium 48
Infliximab 47
Infliximab 47
lysine 47
Dermatol 46
ROS 43
Budesonide 32
Mesalazine 29
Prednisolone 24
G-CSF 23
lactose 18
MAP 16
IL-11 14
ascorbate 14
Dasatinib 13
vitamin E 12
NADH 12
Indomethacin 11
Tacrolimus 11
Sulphasalazine 10
Leaf 10
Histamine 10
Retinoic acid 10
Asthma 9
Heme 9
Glucagon 9
EPA 9
CCL 8
Gel 8
Ganciclovir 8
niacin 8
Aloe 8
p75 8
Rifaximin 8
IFN-beta 7
ALA 7
IL-1ra 7
Nitric Oxide 7
Prednisone 7
CPT-11 7
Mirtazapine 7
CTX 7
Rosiglitazone 7
Paraffin 6
Growth hormone 6
Cardiovasc 6
citric acid 6
Growth hormone 6
Adalimumab 6
Copaxone 6
ICI 6
Epigallocatechin 5
Rebamipide 5
Glutathione 5
Rutin 5
Kayexalate 5
Monit 5
TAK 5
GEO 4
Triclosan 4
CTX 4
AZT 4
Alliance 4
Aminoguanidine 4
Rituximab 4
Gastro 4
CTT 4
Imodium 4
Glycyrrhiza 4
DPA 4
Ketotifen 4
Anakinra 4
CTX 4
Portal 4
CED 4
PFA 4
Imodium 4
Angiotensin II 4
ABC 4
Ethanol 3
Fluconazole 3
Rolipram 3
Cellcept 3
Auranofin 3
Sucralfate 3
Rifalazil 3
KGF 3
Myricetin 3
Cellcept 3
Misoprostol 3
TAC 3
DNase I 3
Zileuton 3
Dial 3
AMC 3
Dipentum 3
caffeine 3
Ginseng 3
Cidofovir 3
ZnO 3
Ginger 3
Ranitidine 3
Amoxicillin 3
Nephron 3
Sodium propionate 3
Serum albumin 3
Vitamin A 3
Vitamin E 3
Natalizumab 2
Bortezomib 2
Omeprazole 2
PDL 2
Spectrum 2
ETS 2
Captopril 2
ROC 2
Spectrum 2
PFT 2
Olive oil 2
Arsenic trioxide 2
Vandetanib 2
Mercaptopurine 2
Adriamycin 2
Lumiracoxib 2
Troglitazone 2
Piperacillin 2
TAT 2
CAM 2
Giardiasis 2
Phenytoin 2
Bactrim 2
Simvastatin 2
IPM 2
Azithromycin 2
Nimesulide 2
Frontal 2
Rimonabant 2
Gabapentin 2
ADR 2
Ronidazole 2
Mycophenolic acid 2
Bromelain 2
BH4 2
Fenbufen 2
Atropine 2
Vardenafil 2
Irinotecan 2
Ipecac 2
Acyclovir 2
Olmesartan 2
Doxycycline 2
PMPA 2
ENT 2
EE2 2
more...
Enzyme
peroxidase 1152
mitogen-activated protein kinase 325
superoxide dismutase 184
ERK 147
catalase 116
caspase-3 94
caspase-1 86
NO synthase 80
focal adhesion kinase 74
luciferase 64
alkaline phosphatase 63
protein kinase 62
APC 50
glutathione peroxidase 45
PARP 43
AMP-activated protein kinase 42
IKK 39
NADPH oxidase 38
alanine aminotransferase 37
MIP 37
lactate dehydrogenase 36
NADPH oxidase 35
NOS 34
trypsin 33
protein kinase C 33
MEK 32
reverse transcriptase 31
proteasome 29
lysozyme 27
arginase 27
AMPK 26
AMPK 26
calcineurin 25
aspartate aminotransferase 22
lipoxygenase 22
ACS 22
phospholipase A2 22
thrombin 21
myosin light chain kinase 21
caspase-8 20
phosphatidylinositol 3-kinase 17
heme oxygenase 17
P-glycoprotein 17
phosphodiesterase 16
glutathione S-transferase 16
MAP 15
tryptase 15
collagenase 15
NQO1 14
xanthine oxidase 14
neutrophil elastase 14
GSK 14
lipase 14
ATPase 12
elastase 11
guanylate cyclase 11
caspase-9 11
prolyl hydroxylase 11
dipeptidyl peptidase IV 11
phosphoinositide 3-kinase 10
thromboplastin 10
renin 10
beta-glucuronidase 10
RNA polymerase 10
granzyme B 10
adenylate cyclase 10
MMP-3 10
phospholipase C 10
caspase-11 9
caspase-11 9
glutamate dehydrogenase 9
glutamate dehydrogenase 9
glutamate dehydrogenase 9
urease 9
indoleamine 2,3-dioxygenase 9
transglutaminase 8
MMP 8
urease 8
chitinase 8
diamine oxidase 8
aldehyde dehydrogenase 8
Thy1 8
CD10 8
ornithine decarboxylase 8
BMT 7
neuraminidase 7
gamma-glutamyl transpeptidase 7
chymase 7
RNase 7
DNA methyltransferase 7
creatine kinase 7
adenosine deaminase 7
adenosine deaminase 7
glutathione reductase 7
ricin 7
aldehyde dehydrogenase 6
aldehyde dehydrogenase 6
BBE 6
AST 6
tyrosine hydroxylase 6
kallikrein 6
cathepsin B 6
chymotrypsin 6
acetylcholinesterase 6
lactase 6
aldehyde dehydrogenase 6
urokinase-type plasminogen activator 6
aldehyde dehydrogenase 6
15-hydroxyprostaglandin dehydrogenase 6
protein phosphatase 2A 6
sucrase 5
RNase 5
LPL 5
matrix metalloproteinase 9 5
TdT 5
ATP synthase 5
DNA polymerase 5
N-acetyltransferase 5
tyrosinase 5
PTA 5
ACE 5
N-acetylglucosaminyltransferase 5
endonuclease 5
p100 5
gamma-glutamylcysteine synthetase 5
matrix metalloproteinase 2 4
invertase 4
thiopurine methyltransferase 4
acid phosphatase 4
15-lipoxygenase 4
beta-glucosidase 4
sphingosine kinase 4
enolase 4
tryptophan hydroxylase 4
papain 4
monoamine oxidase 4
choline acetyltransferase 4
ADP-ribosyltransferase 4
ADP-ribosyltransferase 4
plasmin 4
TACE 4
thymidine kinase 4
cathepsin D 4
glucose oxidase 4
PDE 4
beta-lactamase 4
bile salt hydrolase 3
complex I 3
caspase-4 3
caspase-4 3
NADPH-diaphorase 3
GRK5 3
legumain 3
monoacylglycerol lipase 3
Alternating 3
demethylase 3
alpha-glucosidase 3
methionine adenosyltransferase 3
Mg2+-ATPase 3
matriptase 3
more...
Compound
sodium 3278
sulfate 2761
Dec 1345
Clin 1252
TNF 1043
water 940
DSS 591
DNA 533
oxygen 346
nitric oxide 323
acetic acid 321
ethanol 257
ASA 159
barium 158
phosphate 130
calcium 128
acetate 124
GSH 111
GSH 111
glucose 104
iron 98
arginine 93
PGE2 80
Dextran 80
salt 79
ATP 76
tyrosine 74
PGE 70
hydrogen 66
vitamin D 66
His 65
lysine 59
nitrogen 58
galactose 56
retinoic acid 56
zinc 55
creatinine 53
THP 52
nitrate 52
THP 51
butyric acid 50
Sulfasalazine 48
tryptophan 48
leucine 46
cysteine 46
serine 45
tryptophan 45
potassium 44
tryptophan 44
tryptophan 44
glutamine 42
5-HT 42
Vancomycin 42
Sodium 40
NIDA 39
PEG 39
sulfuric acid 38
Curcumin 37
alanine 37
MDA 34
TNB 33
Azathioprine 32
CO2 32
Phe 31
Cyclosporine 30
selenium 30
NAD 29
urea 28
methionine 28
cAMP 28
Mesalamine 27
nicotinamide 27
salicylic acid 26
H2S 26
H2O2 26
benzene 26
EDTA 25
EDTA 25
threonine 25
Dexamethasone 25
Gb3 24
ASC 24
CAT 24
NAD 24
Prednisolone 24
Clindamycin 23
ADP 23
ADP 23
1,2-dimethylhydrazine 23
ADP 23
silver 23
proline 22
ACS 22
ACS 22
FK506 22
NADPH 21
NADPH 21
ADP-ribose 21
MEK 21
NKT 21
Gly 20
ANCA 20
Resveratrol 20
butyric acid 19
Berberine 19
butyric acid 18
TOF 18
PEG 18
copper 18
Pac 17
formaldehyde 17
Vitamin D 17
AMP 16
Methotrexate 16
Melatonin 16
Substance P 16
N-acetylcysteine 16
dUTP 16
MIC 16
Lactate 16
cGMP 16
bromide 15
CAT 15
GalNAc 15
Asp 15
MAP 15
MTT 15
CAT 15
HCl 14
Azoxymethane 14
Glutamine 14
COX 14
Hematoxylin 14
Optimal 14
Mycophenolate mofetil 14
8-OHdG 14
Salt 13
Adenosine 13
Malondialdehyde 13
pyridine 13
PMA 13
xylose 13
ammonium 13
ammonia 13
GTP 12
hyaluronic acid 12
Leukotriene B4 12
NADH 12
Nicotine 12
manganese 11
PMA 11
DBA 11
Lactic acid 11
ethyl acetate 11
ACTH 11
2-oxoglutarate 11
palmitic acid 11
carbonate 11
hydroxide 11
DHA 11
more...