Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0008370 (cholestasis)
 9,378 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
bile salt export pump 0.010
ABCB11 0.007
BSEP 0.006
Alagille syndrome 0.004
ABCB4 0.004
citrin 0.003
SLC25A13 0.003
PFIC 0.002
VPS33B 0.002
Citrin 0.002
MDR3 0.002
farnesoid X receptor 0.002
multidrug resistance protein 3 0.001
alkaline phosphatase 0.001
MDR2 0.001
FXR 0.001
gamma-glutamyl transpeptidase 0.000
alanine aminotransferase 0.000
NTCP 0.000
BCS1 0.000
multidrug resistance protein 2 0.000
BCS1L 0.000
gamma-glutamyltransferase 0.000
aspartate aminotransferase 0.000
MRP2 0.000
TJP2 0.000
ICP 0.000
multidrug resistance-associated protein 0.000
Farnesoid X receptor 0.000
MRP3 0.000
mitochondrial solute carrier protein 0.000
JAG1 0.000
ATP8B2 0.000
Cirhin 0.000
sodium/bile acid cotransporter 0.000
SHP 0.000
PBC 0.000
CYP7A1 0.000
USP53 0.000
protoporphyria 0.000
vacuolar protein sorting 33B 0.000
ABCB4 protein 0.000
NR1H4 0.000
TGR5 0.000
glutamate carrier 0.000
gamma-glutamyltranspeptidase 0.000
OSTalpha 0.000
SLC10A1 0.000
TBC1D3C 0.000
Lst-1 0.000
mitochondrial aspartate-glutamate carrier protein 0.000
AST 0.000
DGUOK 0.000
pregnane X receptor 0.000
AKR1D1 0.000
ASBT 0.000
TPN 0.000
bile acid receptor 0.000
GGT 0.000
ATP8B3 0.000
CYP8B1 0.000
ITFG2 0.000
C14orf133 0.000
PXR 0.000
constitutive androstane receptor 0.000
Aquaporin-8 0.000
OSTbeta 0.000
myosin VB 0.000
ATP8B4 0.000
ATP8A1 0.000
myosin 5B 0.000
oxysterol 7alpha-hydroxylase 0.000
MRP4 0.000
HIVEP1 0.000
nuclear receptor 0.000
FGF19 0.000
canalicular multispecific organic anion transporter 0.000
ABCC2 0.000
ST3GalV 0.000
IDH3G 0.000
more...
Disease
cholestasis 1.000
biliary atresia 0.007
cholangitis 0.007
primary biliary cirrhosis 0.006
liver disease 0.006
biliary obstruction 0.005
Intrahepatic cholestasis 0.004
pruritus 0.004
primary sclerosing cholangitis 0.003
Benign recurrent intrahepatic cholestasis 0.003
cirrhosis 0.003
hepatitis 0.002
PFIC1 0.002
obstructive jaundice 0.002
PFIC2 0.002
Vanishing bile duct syndrome 0.002
hyperbilirubinemia 0.002
PFIC3 0.002
CTLN2 0.002
Neonatal cholestasis 0.002
Extrahepatic cholestasis 0.002
Cholestatic liver disease 0.001
gallstones 0.001
cholangiolitis 0.001
viral hepatitis 0.001
choledocholithiasis 0.001
citrullinemia 0.001
liver fibrosis 0.001
portal hypertension 0.001
Dubin-Johnson syndrome 0.001
Stauffer's syndrome 0.000
acute hepatitis 0.000
Conjugated hyperbilirubinemia 0.000
chronic liver disease 0.000
cholemia 0.000
Cholestatic hepatitis 0.000
NAIC 0.000
bile duct stenosis 0.000
inspissated bile syndrome 0.000
pancreatitis 0.000
chronic active hepatitis 0.000
Sclerosing cholangitis 0.000
fatty liver 0.000
vitamin K deficiency 0.000
hepatosis 0.000
Liver cholestasis 0.000
chronic pancreatitis 0.000
cholestatic cirrhosis 0.000
cholecystitis 0.000
Secondary biliary cirrhosis 0.000
Hepatic amyloidosis 0.000
chronic hepatitis 0.000
erythropoietic protoporphyria 0.000
biliary tract disease 0.000
Giant cell hepatitis 0.000
Hardikar syndrome 0.000
Suppurative cholangitis 0.000
Secondary sclerosing cholangitis 0.000
Secondary hyperlipidemia 0.000
malabsorption 0.000
sepsis 0.000
drug-induced hepatitis 0.000
sepsis 0.000
Interstitial pancreatitis 0.000
Neonatal conjugated hyperbilirubinemia 0.000
cholecystectasia 0.000
syndrome; viral 0.000
Primary cholangitis 0.000
Conjugated bilirubinaemia 0.000
Cholangitis lenta 0.000
short bowel syndrome 0.000
bronze baby syndrome 0.000
Wilson's disease 0.000
neonatal jaundice 0.000
alcoholic hepatitis 0.000
Acute fatty liver of pregnancy 0.000
Syncytial giant cell hepatitis 0.000
Bacterial cholangitis 0.000
Bile duct stricture 0.000
Other liver diseases 0.000
more...
Symptom
hepatomegaly 0.001
dark urine 0.000
Pruritus of pregnancy 0.000
hyperemesis gravidarum 0.000
Generalized pruritus 0.000
jaundice of the skin 0.000
Bile pigment retention 0.000
Hepatocellular jaundice 0.000
abdominal pain 0.000
Nasal discomfort 0.000
hepatosplenomegaly 0.000
Upper abdominal pain 0.000
Courvoisier's sign 0.000
splenomegaly 0.000
liver pain 0.000
right upper quadrant pain 0.000
Unexplained abdominal pain 0.000
Musculoskeletal discomfort 0.000
vomiting 0.000
fatigue 0.000
anorexia 0.000
diarrhea 0.000
Murphy's sign 0.000
asthenia 0.000
hypoproteinemia 0.000
Intermenstrual bleeding 0.000
Fetal bradycardia 0.000
epigastric pain 0.000
abdominal discomfort 0.000
nausea 0.000
impaired motor coordination 0.000
stomach cramps 0.000
regurgitation 0.000
pain 0.000
hypotonia 0.000
painful swallowing 0.000
Ill 0.000
lethargy 0.000
generalized abdominal pain 0.000
chills 0.000
respiratory distress 0.000
lassitude 0.000
ophthalmoplegia 0.000
Decreased activity 0.000
hyperemesis 0.000
polydipsia 0.000
generalized rash 0.000
menometrorrhagia 0.000
acute abdominal pain 0.000
Neurologic symptoms 0.000
cachexia 0.000
polyuria 0.000
colic 0.000
arthralgia 0.000
anesthesia 0.000
intestinal bleeding 0.000
fever of unknown origin 0.000
abdominal cramps 0.000
ataxia 0.000
oliguria 0.000
sore throat 0.000
collapse 0.000
loin pain 0.000
Physical findings 0.000
weakness 0.000
cough 0.000
dry skin 0.000
nausea and vomiting 0.000
seizures 0.000
discomfort 0.000
stomach pain 0.000
rundown 0.000
arm pain 0.000
decreased appetite 0.000
discomfort 0.000
night sweats 0.000
retching 0.000
Gastrointestinal symptoms 0.000
pleuritic chest pain 0.000
spasm 0.000
more...
Drug
Quetiapine hemifumarate 0.000
Sulfobromophthalein sodium 0.000
Nicomol 0.000
Iodipamide 0.000
Portal 0.000
Propafenone hydrochloride 0.000
PTC 0.000
Propafenone HCl 0.000
Colestimide 0.000
Cupric sulfate 0.000
vitamin E 0.000
Platelet concentrate 0.000
cetrorelix acetate 0.000
Mebrofenin 0.000
Naltrexone hydrochloride 0.000
Troglitazone 0.000
CFDN 0.000
Sincalide 0.000
Mangafodipir trisodium 0.000
Xipamide 0.000
Augmentin 0.000
Sodium phenylbutyrate 0.000
Protein hydrolysate 0.000
Augmentin 0.000
Eldepryl 0.000
Nitisinone 0.000
Medicon 0.000
Eldepryl 0.000
Cefpiramide 0.000
Vitamin K 0.000
Soybean oil 0.000
Neoral 0.000
Mercaptopurine 0.000
Bezafibrate 0.000
Amoxicillin 0.000
Secretin 0.000
Cilastatin 0.000
Lariam 0.000
Zinc acetate 0.000
Liposyn 0.000
Cerezyme 0.000
Lariam 0.000
Rhubarb 0.000
Nafcillin 0.000
Fotemustine 0.000
Temocillin 0.000
Zileuton 0.000
Ceruletide 0.000
Nimesulide 0.000
Velban 0.000
Narcan 0.000
Gold sodium thiomalate 0.000
Meconium 0.000
Dazoxiben 0.000
Estrogens 0.000
Phenprocoumon 0.000
Pegasys 0.000
AMC 0.000
Cremophor EL 0.000
Malonaldehyde 0.000
Miglustat 0.000
Mesalazine 0.000
Cerezyme 0.000
Swertia 0.000
Vitamin E 0.000
Sesamol 0.000
Emodin 0.000
Proglumide 0.000
DMAP 0.000
Tenoxicam 0.000
NAH 0.000
ABC 0.000
Adenosine triphosphate 0.000
Emodin 0.000
NLF 0.000
EE2 0.000
CFX 0.000
Methyldopa 0.000
Dilantin 0.000
Calcipotriol 0.000
more...
Enzyme
gamma-glutamyl transpeptidase 0.001
alkaline phosphatase 0.001
alanine aminotransferase 0.001
aspartate aminotransferase 0.000
CYP7A1 0.000
AST 0.000
CYP8B1 0.000
sedoheptulokinase 0.000
transpeptidase 0.000
Mg2+-ATPase 0.000
CYP27A1 0.000
5'-nucleotidase 0.000
ganglioside galactosyltransferase 0.000
UDP-glucuronosyltransferase 0.000
lecithin:cholesterol acyltransferase 0.000
leucine aminopeptidase 0.000
lactate dehydrogenase 0.000
sorbitol dehydrogenase 0.000
ferrochelatase 0.000
CYP7B1 0.000
5beta-reductase 0.000
nucleotidase 0.000
argininosuccinate synthetase 0.000
cholesterol acyltransferase 0.000
P-glycoprotein 0.000
histidase 0.000
ATPase 0.000
ceruloplasmin 0.000
alanine aminopeptidase 0.000
porphobilinogenase 0.000
CYP3A4 0.000
gamma-glutamylcysteine synthetase 0.000
glycine N-methyltransferase 0.000
dimethylarginine dimethylaminohydrolase 0.000
catalase 0.000
glycerol 3-phosphate dehydrogenase 0.000
cholinesterase 0.000
isovaleryl-CoA dehydrogenase 0.000
hexosaminidase 0.000
peroxidase 0.000
phosphatidylethanolamine N-methyltransferase 0.000
type III procollagen 0.000
pyruvate dehydrogenase 0.000
glutathione peroxidase 0.000
ALA synthase 0.000
alpha-methylacyl-CoA racemase 0.000
superoxide dismutase 0.000
6beta-hydroxylase 0.000
arginase 0.000
demethylase 0.000
beta-glucuronidase 0.000
betaine-homocysteine methyltransferase 0.000
lecithin:retinol acyltransferase 0.000
lipase 0.000
3-hydroxyacyl-CoA dehydrogenase 0.000
mevalonate kinase 0.000
CPR 0.000
glutamate dehydrogenase 0.000
glutamate dehydrogenase 0.000
glutamate dehydrogenase 0.000
phospholipase A1 0.000
3alpha-hydroxysteroid dehydrogenase 0.000
TSR 0.000
mitogen-activated protein kinase 0.000
heme oxygenase 0.000
GM3 synthase 0.000
glutamic dehydrogenase 0.000
IMP dehydrogenase 0.000
NADH-cytochrome b5 reductase 0.000
NOS 0.000
isoleucyl-tRNA synthetase 0.000
bile salt hydrolase 0.000
glucose-6-phosphatase 0.000
lysophosphatidylcholine acyltransferase 0.000
CCS 0.000
AMP-activated protein kinase 0.000
caspase-3 0.000
caspase-8 0.000
S-adenosyl-L-homocysteine hydrolase 0.000
glutathione S-transferase 0.000
more...
Compound
Ursodeoxycholic acid 0.004
ANI 0.001
Lithocholic acid 0.000
Glycochenodeoxycholic acid 0.000
Chenodeoxycholic acid 0.000
Taurolithocholate 0.000
Tauroursodeoxycholic acid 0.000
Taurocholate 0.000
Parenteral 0.000
Taurochenodeoxycholate 0.000
Yangonin 0.000
Bilirubin diglucuronide 0.000
Estradiol-17beta-glucuronide 0.000
Dipropyl sulfide 0.000
Yangonin 0.000
Cholic acid 0.000
salt 0.000
Sulfolithocholylglycine 0.000
Glycolithocholic acid 0.000
Varanic acid 0.000
Sulfobromophthalein 0.000
cholan-24-oic acid 0.000
Isoursodeoxycholic acid 0.000
Glycoursodeoxycholate 0.000
cholan-24-oic acid 0.000
Bilirubin 0.000
Glycodeoxycholate 0.000
Clin 0.000
taurolithocholate 3-sulfate 0.000
GW 4064 0.000
ALP 0.000
TMCA 0.000
2-nonynoic acid 0.000
Di-n-butyltin dichloride 0.000
IDA 0.000
6-ECDCA 0.000
TMCA 0.000
Estrogen 0.000
2-octynoic acid 0.000
Glycocholic acid 0.000
Midecamycin 0.000
Midecamycin 0.000
1-bromoheptane 0.000
CCl4 0.000
Flucloxacillin 0.000
Griseofulvin 0.000
PELS 0.000
Griseofulvin 0.000
GPT 0.000
Miroestrol 0.000
Harmol 0.000
imidazo[2,1-b][1,3]thiazole-5-carbaldehyde 0.000
Stains-all 0.000
Rifampicin 0.000
Cyclosporine 0.000
Chlorpromazine 0.000
4-phenylbutanoic acid 0.000
Thiobenzamide 0.000
Tolazamide 0.000
M1A 0.000
Sporidesmin 0.000
sodium 0.000
estra-1,3,5(10)-triene-3,17-diol 0.000
NAMS 0.000
16 alpha-hydroxypregnenolone 0.000
Ammonium perfluorooctanoate 0.000
Rhodanine 0.000
copper 0.000
Methyleugenol 0.000
Paeoniflorin 0.000
GSH 0.000
GSH 0.000
Scoparone 0.000
1,2-dimethoxybenzene 0.000
adenosylmethionine 0.000
Dec 0.000
Fenistil 0.000
Phalloidin 0.000
bromobenzene 0.000
DHM 0.000
more...