Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0008370 (
cholestasis
)
9,378
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
mitochondrial aspartate-glutamate carrier protein
11.7
Lst-1
11.7
TBC1D3C
11.7
PFIC
11.4
USP53
11.1
VPS33B
11.1
mitochondrial solute carrier protein
11.0
Citrin
11.0
ABCB11
10.8
sodium/bile acid cotransporter
10.7
ITFG2
10.7
C14orf133
10.7
SLC25A13
10.7
multidrug resistance protein 3
10.6
BSEP
10.5
ABCB4 protein
10.5
vacuolar protein sorting 33B
10.5
bile salt export pump
10.5
citrin
10.5
ATP8B2
10.4
ABCB4
10.4
myosin 5B
10.1
ATP8B4
10.1
myosin VB
10.1
MDR3
10.0
BCS1
9.9
ATP8B3
9.9
Alagille syndrome
9.9
Cirhin
9.9
MDR2
9.8
ST3GalV
9.7
IDH3G
9.7
BCS1L
9.7
TJP2
9.6
hepatic nuclear factor 4 alpha
9.4
PDZD4
9.4
HIVEP1
9.4
OSTalpha
9.4
MRGPRX1
9.4
GGT3
9.4
OSTbeta
9.2
ATP8A1
9.1
TTC26
9.1
LPEAT2
9.1
Cholesterol acyltransferase
9.1
PAQR10
9.1
HSD3B7
9.0
organic solute transporter alpha
8.9
ATP10D
8.9
SPOCK3
8.9
pregnancy specific beta-1-glycoprotein
8.9
SRPK3
8.9
DGUOK
8.9
AKR1D1
8.9
oxysterol 7alpha-hydroxylase
8.8
Aquaporin-8
8.8
Multidrug resistance protein 3
8.7
SSR4
8.7
protein phosphatase 2 regulatory subunit B
8.7
ATP11B
8.7
NR1H4
8.7
TEB4
8.6
SLC10A1
8.6
ATP11A
8.6
BCMO
8.6
CDC50B
8.6
farnesoid X receptor
8.5
FXR
8.5
Farnesoid X receptor
8.5
multidrug resistance protein 2
8.5
glutamate carrier
8.4
TMED7
8.4
claudin 15
8.4
KIF12
8.4
NBEAL2
8.4
protoporphyria
8.3
CDC50A
8.3
RFX6
8.3
GLI-similar 3
8.3
FUCA2
8.3
more...
Disease
cholecystectasia
11.7
syndrome; viral
11.7
Conjugated bilirubinaemia
11.7
Neonatal conjugated hyperbilirubinemia
11.7
Primary cholangitis
11.7
Interstitial pancreatitis
11.7
cholestasis
11.7
Cholangitis lenta
11.7
PFIC3
11.7
PFIC1
11.6
Benign recurrent intrahepatic cholestasis
11.5
PFIC2
11.4
Vanishing bile duct syndrome
11.4
Neonatal cholestasis
11.3
Intrahepatic cholestasis
11.1
Liver cholestasis
11.0
Extrahepatic cholestasis
10.9
NAIC
10.9
Cholestatic liver disease
10.8
hepatocholangitis
10.7
Acute cholestatic hepatitis
10.7
Suppurative cholangitis
10.7
Drug-induced intrahepatic cholestasis
10.7
Hardikar syndrome
10.7
Cholestasis and jaundice
10.7
Early cirrhosis
10.7
CTLN2
10.6
Conjugated hyperbilirubinemia
10.6
cholemia
10.6
cholangiolitis
10.5
Stauffer's syndrome
10.5
Cholestatic hepatitis
10.4
inspissated bile syndrome
10.3
Secondary hyperlipidemia
10.1
Hepatic amyloidosis
10.1
Gastrointestinal hypomotility
10.1
Other liver diseases
10.1
BRIC2
10.1
Bile duct stricture
10.1
Secondary biliary cirrhosis
10.1
Syncytial giant cell hepatitis
10.1
Bacterial cholangitis
10.1
Secondary sclerosing cholangitis
9.8
Hepatic artery occlusion
9.7
Neonatal Graves' disease
9.7
bronze baby syndrome
9.6
fibrocystic disease of the pancreas
9.6
Hepatic osteodystrophy
9.5
Osteopenia of prematurity
9.4
Toxic myocarditis
9.4
Hypotriglyceridemia
9.4
Giant cell hepatitis
9.3
biliary atresia
9.2
Sclerosing cholangitis
9.2
Pancreatic enlargement
9.1
cholestatic cirrhosis
9.1
galactosuria
9.0
Biliary sludge
9.0
Dubin-Johnson syndrome
8.9
cochlear disorder
8.9
Regenerative anemia
8.9
Hepatic vein stenosis
8.9
AIDS cholangiopathy
8.9
untreated adult acute lymphoblastic leukemia
8.9
liver failure with encephalopathy
8.9
biliary obstruction
8.9
citrullinemia
8.9
Biliary disease
8.9
bile duct stenosis
8.8
Greenberg dysplasia
8.7
hepatosis
8.7
Classic polyarteritis nodosa
8.7
Papillary stenosis
8.7
Pruritic urticarial papules and plaques of pregnancy
8.7
primary sclerosing cholangitis
8.6
Gallbladder sludge
8.6
Extrahepatic bile ducts
8.6
Plasma cell infiltration
8.6
primary biliary cirrhosis
8.5
Unconjugated hyperbilirubinemia
8.5
more...
Symptom
Hepatocellular jaundice
11.7
Bile pigment retention
11.7
Pruritus of pregnancy
11.1
Nasal discomfort
10.7
jaundice of the skin
9.7
Generalized pruritus
9.5
Courvoisier's sign
9.4
Upper abdominal pain
9.0
liver pain
8.7
Unexplained abdominal pain
8.6
dark urine
8.4
Musculoskeletal discomfort
7.9
hyperemesis gravidarum
7.5
Murphy's sign
6.8
Fetal bradycardia
6.7
Intermenstrual bleeding
6.7
hepatomegaly
6.7
right upper quadrant pain
6.2
stomach cramps
6.1
impaired motor coordination
5.7
painful swallowing
5.7
hepatosplenomegaly
5.5
generalized abdominal pain
5.1
hypoproteinemia
5.0
lassitude
4.6
generalized rash
4.6
splenomegaly
4.6
asthenia
4.5
hyperemesis
4.5
menometrorrhagia
4.4
abdominal discomfort
4.4
abdominal pain
4.4
Decreased activity
4.3
epigastric pain
4.2
Neurologic symptoms
4.2
abdominal cramps
3.7
intestinal bleeding
3.7
anorexia
3.6
polydipsia
3.4
loin pain
3.4
hypotonia
3.4
acute abdominal pain
3.4
Physical findings
3.4
regurgitation
3.3
vomiting
3.2
ophthalmoplegia
3.2
lethargy
3.2
chills
3.1
fever of unknown origin
3.0
polyuria
3.0
colic
2.9
oliguria
2.9
Ill
2.9
stomach pain
2.8
rundown
2.8
arm pain
2.7
dry skin
2.7
fatigue
2.7
nausea
2.6
retching
2.6
sore throat
2.6
cachexia
2.6
diarrhea
2.6
Gastrointestinal symptoms
2.5
decreased appetite
2.5
pleuritic chest pain
2.5
night sweats
2.5
Fluctuation
2.5
arthralgia
2.4
limb pain
2.3
leg edema
2.3
anosmia
2.2
chest tightness
2.1
renal colic
2.1
respiratory distress
2.1
rigors
2.0
pallor
2.0
dry eye
2.0
clubbing
1.9
acute abdomen
1.7
more...
Drug
Quetiapine hemifumarate
11.7
Nicomol
10.1
Sulfobromophthalein sodium
10.1
Propafenone hydrochloride
8.0
Propafenone HCl
7.9
Iodipamide
7.9
Cupric sulfate
7.7
Colestimide
7.7
Platelet concentrate
7.6
cetrorelix acetate
7.6
Mebrofenin
7.6
Naltrexone hydrochloride
7.5
CFDN
7.3
Sincalide
7.2
Mangafodipir trisodium
7.1
Xipamide
7.1
Sodium phenylbutyrate
6.9
Protein hydrolysate
6.9
Nitisinone
6.8
Eldepryl
6.8
Medicon
6.7
Eldepryl
6.6
Cefpiramide
6.6
Mercaptopurine
6.4
Cilastatin
6.3
Lariam
6.2
Zinc acetate
6.2
Soybean oil
6.0
Augmentin
6.0
Cerezyme
5.9
Augmentin
5.9
Lariam
5.9
Liposyn
5.9
Troglitazone
5.8
Nafcillin
5.8
Rhubarb
5.7
Temocillin
5.7
Fotemustine
5.7
Bezafibrate
5.6
Ceruletide
5.6
Velban
5.5
Narcan
5.5
Zileuton
5.5
Gold sodium thiomalate
5.4
Dazoxiben
5.3
Neoral
5.3
PTC
5.3
Phenprocoumon
5.2
Pegasys
5.2
Malonaldehyde
5.1
Miglustat
5.1
Nimesulide
5.1
Cerezyme
5.0
Secretin
5.0
Meconium
5.0
Mesalazine
4.9
Amoxicillin
4.9
Sesamol
4.9
Swertia
4.8
Proglumide
4.8
Tenoxicam
4.8
NAH
4.8
Portal
4.7
Vitamin K
4.7
NLF
4.4
Cremophor EL
4.4
CFX
4.4
Emodin
4.4
Methyldopa
4.4
Dilantin
4.4
Calcipotriol
4.4
Butorphanol
4.3
Inderal
4.2
Enfuvirtide
4.2
Lipidex
4.2
Emodin
4.1
Cetrorelix
4.1
Pefloxacin
4.1
AMC
4.1
Micafungin
4.1
more...
Enzyme
sedoheptulokinase
9.4
CYP8B1
8.4
ganglioside galactosyltransferase
8.1
CYP7A1
7.0
gamma-glutamyl transpeptidase
7.0
5beta-reductase
6.5
CYP7B1
6.3
CYP27A1
6.2
porphobilinogenase
5.9
histidase
5.9
transpeptidase
5.8
alanine aminotransferase
5.8
Mg2+-ATPase
5.7
AST
5.6
aspartate aminotransferase
5.6
alkaline phosphatase
5.5
glycine N-methyltransferase
5.4
lecithin:cholesterol acyltransferase
5.3
argininosuccinate synthetase
5.3
ferrochelatase
5.2
isovaleryl-CoA dehydrogenase
5.2
sorbitol dehydrogenase
5.1
glycerol 3-phosphate dehydrogenase
5.1
dimethylarginine dimethylaminohydrolase
5.1
nucleotidase
5.0
5'-nucleotidase
5.0
leucine aminopeptidase
5.0
phosphatidylethanolamine N-methyltransferase
4.9
alpha-methylacyl-CoA racemase
4.9
alanine aminopeptidase
4.8
6beta-hydroxylase
4.7
UDP-glucuronosyltransferase
4.7
cholesterol acyltransferase
4.5
betaine-homocysteine methyltransferase
4.4
lecithin:retinol acyltransferase
4.4
type III procollagen
4.3
gamma-glutamylcysteine synthetase
4.2
TSR
4.2
3alpha-hydroxysteroid dehydrogenase
4.2
mevalonate kinase
4.1
phospholipase A1
4.1
ALA synthase
4.1
GM3 synthase
4.0
glutamic dehydrogenase
3.9
3-hydroxyacyl-CoA dehydrogenase
3.9
isoleucyl-tRNA synthetase
3.8
bile salt hydrolase
3.8
lysophosphatidylcholine acyltransferase
3.7
NADH-cytochrome b5 reductase
3.7
S-adenosyl-L-homocysteine hydrolase
3.6
biliverdin reductase
3.6
ceruloplasmin
3.6
fumarylacetoacetate hydrolase
3.6
CCS
3.5
IMP dehydrogenase
3.5
hexosaminidase
3.4
CYP3A4
3.3
methionine adenosyltransferase
3.3
caspase-11
3.3
caspase-11
3.3
P-glycoprotein
3.2
fructokinase
3.2
PME
3.2
nucleotide pyrophosphatase
3.2
3-hydroxy-3-methylglutaryl-CoA reductase
3.2
methionyl-tRNA synthetase
3.1
PMT
3.1
arginase
3.0
pyruvate dehydrogenase
3.0
carnitine acetyltransferase
3.0
choline kinase
2.9
lactate dehydrogenase
2.9
lactic acid dehydrogenase
2.9
polyamine oxidase
2.9
uroporphyrinogen decarboxylase
2.9
cholesterol esterase
2.8
lactic acid dehydrogenase
2.8
caspase-6
2.8
HMG-CoA synthase
2.8
glutamate dehydrogenase
2.8
more...
Compound
Estradiol-17beta-glucuronide
10.7
Dipropyl sulfide
10.7
Sulfolithocholylglycine
10.1
Varanic acid
10.1
Glycolithocholic acid
10.1
Bilirubin diglucuronide
9.9
Taurolithocholate
9.8
Ursodeoxycholic acid
9.7
Glycoursodeoxycholate
9.7
Glycochenodeoxycholic acid
9.7
Isoursodeoxycholic acid
9.7
Yangonin
9.7
Yangonin
9.5
GW 4064
9.4
Lithocholic acid
9.2
Glycodeoxycholate
9.1
2-nonynoic acid
9.1
Taurochenodeoxycholate
9.1
taurolithocholate 3-sulfate
9.0
6-ECDCA
8.9
TMCA
8.7
Di-n-butyltin dichloride
8.6
ANI
8.6
Sulfobromophthalein
8.6
TMCA
8.4
Chenodeoxycholic acid
8.3
Tauroursodeoxycholic acid
8.2
Midecamycin
8.1
Midecamycin
8.1
2-octynoic acid
8.1
1-bromoheptane
8.0
Taurocholate
7.9
cholan-24-oic acid
7.9
Miroestrol
7.8
Harmol
7.8
imidazo[2,1-b][1,3]thiazole-5-carbaldehyde
7.8
cholan-24-oic acid
7.8
Tolazamide
7.7
Thiobenzamide
7.7
Sporidesmin
7.6
PELS
7.6
Glycocholic acid
7.6
estra-1,3,5(10)-triene-3,17-diol
7.6
NAMS
7.5
16 alpha-hydroxypregnenolone
7.5
Cholic acid
7.5
Ammonium perfluorooctanoate
7.4
M1A
7.4
Flucloxacillin
7.3
Rhodanine
7.3
1,2-dimethoxybenzene
7.2
4-phenylbutanoic acid
7.2
Fenistil
7.1
Methyleugenol
7.1
Scoparone
7.0
Stains-all
7.0
Phorone
7.0
Cadinene
6.9
M 14
6.9
Phorone
6.9
Acar
6.8
Rufloxacin
6.8
Diethyl maleate
6.7
Dianabol
6.6
Infecundin
6.6
DHM
6.5
Griseofulvin
6.5
Griseofulvin
6.5
3-O-methyldopamine
6.3
IDA
6.3
Cilastatin
6.3
Naratriptan
6.3
Parenteral
6.3
Bilirubin
6.2
Cholestanol
6.2
Lumicolchicine
6.2
Stanozolol
6.2
Cloxacillin
6.1
Paeoniflorin
6.1
Stanozolol
6.1
more...