Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0008370 (
cholestasis
)
9,378
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
mitochondrial aspartate-glutamate carrier protein
11.7
TBC1D3C
11.7
Lst-1
11.7
PFIC
11.4
USP53
11.1
VPS33B
11.1
mitochondrial solute carrier protein
11.0
Citrin
11.0
ABCB11
10.8
sodium/bile acid cotransporter
10.7
C14orf133
10.7
ITFG2
10.7
SLC25A13
10.7
multidrug resistance protein 3
10.6
BSEP
10.5
ABCB4 protein
10.5
vacuolar protein sorting 33B
10.5
bile salt export pump
10.5
citrin
10.5
ATP8B2
10.4
ABCB4
10.4
myosin 5B
10.1
myosin VB
10.1
ATP8B4
10.1
MDR3
10.0
ATP8B3
9.9
BCS1
9.9
Alagille syndrome
9.9
Cirhin
9.9
MDR2
9.8
ST3GalV
9.7
IDH3G
9.7
BCS1L
9.7
TJP2
9.6
OSTalpha
9.4
hepatic nuclear factor 4 alpha
9.4
MRGPRX1
9.4
HIVEP1
9.4
GGT3
9.4
PDZD4
9.4
more...
Disease
Cholangitis lenta
11.7
Interstitial pancreatitis
11.7
Primary cholangitis
11.7
Neonatal conjugated hyperbilirubinemia
11.7
cholecystectasia
11.7
cholestasis
11.7
Conjugated bilirubinaemia
11.7
syndrome; viral
11.7
PFIC3
11.7
PFIC1
11.6
Benign recurrent intrahepatic cholestasis
11.5
PFIC2
11.4
Vanishing bile duct syndrome
11.4
Neonatal cholestasis
11.3
Intrahepatic cholestasis
11.1
Liver cholestasis
11.0
Extrahepatic cholestasis
10.9
NAIC
10.9
Cholestatic liver disease
10.8
hepatocholangitis
10.7
Cholestasis and jaundice
10.7
Drug-induced intrahepatic cholestasis
10.7
Hardikar syndrome
10.7
Early cirrhosis
10.7
Acute cholestatic hepatitis
10.7
Suppurative cholangitis
10.7
CTLN2
10.6
Conjugated hyperbilirubinemia
10.6
cholemia
10.6
cholangiolitis
10.5
Stauffer's syndrome
10.5
Cholestatic hepatitis
10.4
inspissated bile syndrome
10.3
Hepatic amyloidosis
10.1
Other liver diseases
10.1
Syncytial giant cell hepatitis
10.1
Gastrointestinal hypomotility
10.1
Bile duct stricture
10.1
Secondary biliary cirrhosis
10.1
Bacterial cholangitis
10.1
more...
Symptom
Hepatocellular jaundice
11.7
Bile pigment retention
11.7
Pruritus of pregnancy
11.1
Nasal discomfort
10.7
jaundice of the skin
9.7
Generalized pruritus
9.5
Courvoisier's sign
9.4
Upper abdominal pain
9.0
liver pain
8.7
Unexplained abdominal pain
8.6
dark urine
8.4
Musculoskeletal discomfort
7.9
hyperemesis gravidarum
7.5
Murphy's sign
6.8
Fetal bradycardia
6.7
Intermenstrual bleeding
6.7
hepatomegaly
6.7
right upper quadrant pain
6.2
stomach cramps
6.1
impaired motor coordination
5.7
painful swallowing
5.7
hepatosplenomegaly
5.5
generalized abdominal pain
5.1
hypoproteinemia
5.0
lassitude
4.6
generalized rash
4.6
splenomegaly
4.6
asthenia
4.5
hyperemesis
4.5
menometrorrhagia
4.4
abdominal discomfort
4.4
abdominal pain
4.4
Decreased activity
4.3
epigastric pain
4.2
Neurologic symptoms
4.2
abdominal cramps
3.7
intestinal bleeding
3.7
anorexia
3.6
polydipsia
3.4
loin pain
3.4
more...
Drug
Quetiapine hemifumarate
11.7
Nicomol
10.1
Sulfobromophthalein sodium
10.1
Propafenone hydrochloride
8.0
Iodipamide
7.9
Propafenone HCl
7.9
Colestimide
7.7
Cupric sulfate
7.7
cetrorelix acetate
7.6
Platelet concentrate
7.6
Mebrofenin
7.6
Naltrexone hydrochloride
7.5
CFDN
7.3
Sincalide
7.2
Mangafodipir trisodium
7.1
Xipamide
7.1
Sodium phenylbutyrate
6.9
Protein hydrolysate
6.9
Eldepryl
6.8
Nitisinone
6.8
Medicon
6.7
Eldepryl
6.6
Cefpiramide
6.6
Mercaptopurine
6.4
Cilastatin
6.3
Lariam
6.2
Zinc acetate
6.2
Soybean oil
6.0
Augmentin
6.0
Cerezyme
5.9
Augmentin
5.9
Lariam
5.9
Liposyn
5.9
Troglitazone
5.8
Nafcillin
5.8
Rhubarb
5.7
Temocillin
5.7
Fotemustine
5.7
Bezafibrate
5.6
Ceruletide
5.6
more...
Enzyme
sedoheptulokinase
9.4
CYP8B1
8.4
ganglioside galactosyltransferase
8.1
CYP7A1
7.0
gamma-glutamyl transpeptidase
7.0
5beta-reductase
6.5
CYP7B1
6.3
CYP27A1
6.2
porphobilinogenase
5.9
histidase
5.9
transpeptidase
5.8
alanine aminotransferase
5.8
Mg2+-ATPase
5.7
AST
5.6
aspartate aminotransferase
5.6
alkaline phosphatase
5.5
glycine N-methyltransferase
5.4
lecithin:cholesterol acyltransferase
5.3
argininosuccinate synthetase
5.3
ferrochelatase
5.2
isovaleryl-CoA dehydrogenase
5.2
sorbitol dehydrogenase
5.1
glycerol 3-phosphate dehydrogenase
5.1
dimethylarginine dimethylaminohydrolase
5.1
nucleotidase
5.0
5'-nucleotidase
5.0
leucine aminopeptidase
5.0
phosphatidylethanolamine N-methyltransferase
4.9
alpha-methylacyl-CoA racemase
4.9
alanine aminopeptidase
4.8
6beta-hydroxylase
4.7
UDP-glucuronosyltransferase
4.7
cholesterol acyltransferase
4.5
betaine-homocysteine methyltransferase
4.4
lecithin:retinol acyltransferase
4.4
type III procollagen
4.3
gamma-glutamylcysteine synthetase
4.2
TSR
4.2
3alpha-hydroxysteroid dehydrogenase
4.2
mevalonate kinase
4.1
more...
Compound
Dipropyl sulfide
10.7
Estradiol-17beta-glucuronide
10.7
Sulfolithocholylglycine
10.1
Glycolithocholic acid
10.1
Varanic acid
10.1
Bilirubin diglucuronide
9.9
Taurolithocholate
9.8
Ursodeoxycholic acid
9.7
Glycoursodeoxycholate
9.7
Glycochenodeoxycholic acid
9.7
Isoursodeoxycholic acid
9.7
Yangonin
9.7
Yangonin
9.5
GW 4064
9.4
Lithocholic acid
9.2
2-nonynoic acid
9.1
Glycodeoxycholate
9.1
Taurochenodeoxycholate
9.1
taurolithocholate 3-sulfate
9.0
6-ECDCA
8.9
TMCA
8.7
Di-n-butyltin dichloride
8.6
ANI
8.6
Sulfobromophthalein
8.6
TMCA
8.4
Chenodeoxycholic acid
8.3
Tauroursodeoxycholic acid
8.2
Midecamycin
8.1
Midecamycin
8.1
2-octynoic acid
8.1
1-bromoheptane
8.0
Taurocholate
7.9
cholan-24-oic acid
7.9
Harmol
7.8
Miroestrol
7.8
imidazo[2,1-b][1,3]thiazole-5-carbaldehyde
7.8
cholan-24-oic acid
7.8
Tolazamide
7.7
Thiobenzamide
7.7
Sporidesmin
7.6
more...