Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0008370 (cholestasis)
9,378 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein alkaline phosphatase 657 Sep 580 alanine aminotransferase 250 bile salt export pump 217 aspartate aminotransferase 210 Mol 210 albumin 165 ICP 160 farnesoid X receptor 139 ABCB11 133 collagen 128 She 124 Alagille syndrome 122 BSEP 121 gamma-glutamyl transpeptidase 110 ATP 110 endoplasmic reticulum 99 gut 96 microsomal 95 cytokine 94 AST 89 polypeptide 86 ABCB4 84 nuclear receptor 82 insulin 80 gamma-glutamyltransferase 78 citrin 76 GSH 76 prothrombin 74 FXR 71 ATPase 68 cytochrome P450 64 MDR3 64 lactate dehydrogenase 58 multidrug resistance-associated protein 57 MRP2 55 SLC25A13 53 tumor necrosis factor 50 ALP 48 GGT 46 more...

Disease cholestasis 9378 liver disease 1276 cirrhosis 1052 hepatitis 825 pruritus 702 cholangitis 627 primary biliary cirrhosis 532 biliary atresia 381 cancer 363 biliary obstruction 343 gallstones 301 obstructive jaundice 289 sepsis 285 primary sclerosing cholangitis 284 tumor 272 sepsis 272 hyperbilirubinemia 261 viral hepatitis 236 pancreatitis 215 portal hypertension 211 liver fibrosis 211 hepatocellular carcinoma 201 chronic liver disease 199 fatty liver 190 chronic hepatitis 185 acute hepatitis 153 carcinoma 153 diabetes 148 chronic pancreatitis 123 choledocholithiasis 105 cytomegalovirus 104 malabsorption 102 chronic active hepatitis 102 hepatitis B 102 cystic fibrosis 97 ischemia 90 hepatitis C 89 anemia 87 virus infection 86 cholecystitis 85 more...

Symptom abdominal pain 195 hepatomegaly 175 pain 138 fatigue 100 diarrhea 100 vomiting 86 splenomegaly 69 hepatosplenomegaly 59 anorexia 49 anesthesia 46 nausea 43 hyperemesis gravidarum 30 dark urine 29 seizures 25 regurgitation 24 respiratory distress 24 Ill 24 weakness 20 epigastric pain 19 asthenia 18 collapse 18 hypotonia 18 lethargy 15 cough 15 right upper quadrant pain 15 ataxia 14 discomfort 13 analgesia 12 discomfort 12 dyspnea 12 headache 11 abdominal discomfort 11 hypoproteinemia 11 chills 11 arthralgia 11 starvation 10 cachexia 10 ophthalmoplegia 9 nausea and vomiting 8 overweight 8 more...

Drug vitamin E 60 Dermatol 52 Portal 33 PTC 20 NADH 19 ABC 15 lactose 14 EE2 13 Vitamin K 11 ampicillin 11 ROS 11 lysine 11 Cardiovasc 10 Vitamin E 10 ascorbate 10 Troglitazone 9 Estrogens 9 Monit 9 caffeine 8 Leaf 8 Amoxicillin 8 MAP 8 Secretin 7 Ethanol 7 Glutathione 7 AMC 6 Albumin 6 Neoral 6 Prednisolone 5 Dial 5 Augmentin 5 DMAP 5 Tacrolimus 5 IL-2 5 Augmentin 5 Gel 5 Bezafibrate 4 Fraction 4 ALA 4 ENT 4 more...

Enzyme alkaline phosphatase 658 alanine aminotransferase 426 gamma-glutamyl transpeptidase 349 aspartate aminotransferase 302 AST 89 ATPase 77 lactate dehydrogenase 65 catalase 52 peroxidase 50 superoxide dismutase 44 mitogen-activated protein kinase 43 CYP7A1 38 P-glycoprotein 37 5'-nucleotidase 30 glutathione peroxidase 27 UDP-glucuronosyltransferase 25 transpeptidase 24 protein kinase C 24 Mg2+-ATPase 22 luciferase 22 caspase-3 22 cholinesterase 22 protein kinase 21 lipase 20 CYP3A4 19 ERK 18 ceruloplasmin 18 glutathione S-transferase 17 acetylcholinesterase 16 leucine aminopeptidase 15 reverse transcriptase 14 cholesterol acyltransferase 14 lecithin:cholesterol acyltransferase 14 beta-glucuronidase 13 pyruvate dehydrogenase 13 AMP-activated protein kinase 13 acid phosphatase 12 trypsin 12 CYP27A1 12 hexosaminidase 11 more...

Compound Clin 987 Dec 565 salt 312 sodium 239 DNA 182 Ursodeoxycholic acid 153 glucose 147 calcium 139 water 128 copper 125 ATP 110 oxygen 90 GSH 81 GSH 81 iron 77 sulfate 72 methionine 70 nitric oxide 67 Estrogen 63 creatinine 59 ethanol 58 urea 58 arginine 57 acetate 55 Parenteral 55 His 53 vitamin D 53 alanine 52 phosphate 49 ALP 48 TNF 45 galactose 42 ANI 42 nitrogen 37 manganese 37 cAMP 36 adenosylmethionine 35 CCl4 34 ammonia 33 Cyclosporine 33 more...

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