UMLS:C0008370 - FACTA Search

Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0008370 (cholestasis)
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Human Gene/Protein
TBC1D3C	11.7
mitochondrial aspartate-glutamate carrier protein	11.7
Lst-1	11.7
PFIC	11.4
USP53	11.1
VPS33B	11.1
mitochondrial solute carrier protein	11.0
Citrin	11.0
ABCB11	10.8
ITFG2	10.7
sodium/bile acid cotransporter	10.7
C14orf133	10.7
SLC25A13	10.7
multidrug resistance protein 3	10.6
BSEP	10.5
vacuolar protein sorting 33B	10.5
ABCB4 protein	10.5
bile salt export pump	10.5
citrin	10.5
ATP8B2	10.4

Disease
Cholangitis lenta	11.7
Conjugated bilirubinaemia	11.7
Interstitial pancreatitis	11.7
cholestasis	11.7
Neonatal conjugated hyperbilirubinemia	11.7
Primary cholangitis	11.7
syndrome; viral	11.7
cholecystectasia	11.7
PFIC3	11.7
PFIC1	11.6
Benign recurrent intrahepatic cholestasis	11.5
PFIC2	11.4
Vanishing bile duct syndrome	11.4
Neonatal cholestasis	11.3
Intrahepatic cholestasis	11.1
Liver cholestasis	11.0
Extrahepatic cholestasis	10.9
NAIC	10.9
Cholestatic liver disease	10.8
Hardikar syndrome	10.7

Symptom
Hepatocellular jaundice	11.7
Bile pigment retention	11.7
Pruritus of pregnancy	11.1
Nasal discomfort	10.7
jaundice of the skin	9.7
Generalized pruritus	9.5
Courvoisier's sign	9.4
Upper abdominal pain	9.0
liver pain	8.7
Unexplained abdominal pain	8.6
dark urine	8.4
Musculoskeletal discomfort	7.9
hyperemesis gravidarum	7.5
Murphy's sign	6.8
Fetal bradycardia	6.7
Intermenstrual bleeding	6.7
hepatomegaly	6.7
right upper quadrant pain	6.2
stomach cramps	6.1
impaired motor coordination	5.7

Drug
Quetiapine hemifumarate	11.7
Sulfobromophthalein sodium	10.1
Nicomol	10.1
Propafenone hydrochloride	8.0
Iodipamide	7.9
Propafenone HCl	7.9
Cupric sulfate	7.7
Colestimide	7.7
cetrorelix acetate	7.6
Platelet concentrate	7.6
Mebrofenin	7.6
Naltrexone hydrochloride	7.5
CFDN	7.3
Sincalide	7.2
Mangafodipir trisodium	7.1
Xipamide	7.1
Sodium phenylbutyrate	6.9
Protein hydrolysate	6.9
Eldepryl	6.8
Nitisinone	6.8

Enzyme
sedoheptulokinase	9.4
CYP8B1	8.4
ganglioside galactosyltransferase	8.1
CYP7A1	7.0
gamma-glutamyl transpeptidase	7.0
5beta-reductase	6.5
CYP7B1	6.3
CYP27A1	6.2
porphobilinogenase	5.9
histidase	5.9
transpeptidase	5.8
alanine aminotransferase	5.8
Mg2+-ATPase	5.7
AST	5.6
aspartate aminotransferase	5.6
alkaline phosphatase	5.5
glycine N-methyltransferase	5.4
lecithin:cholesterol acyltransferase	5.3
argininosuccinate synthetase	5.3
ferrochelatase	5.2

Compound
Estradiol-17beta-glucuronide	10.7
Dipropyl sulfide	10.7
Sulfolithocholylglycine	10.1
Varanic acid	10.1
Glycolithocholic acid	10.1
Bilirubin diglucuronide	9.9
Taurolithocholate	9.8
Ursodeoxycholic acid	9.7
Isoursodeoxycholic acid	9.7
Yangonin	9.7
Glycochenodeoxycholic acid	9.7
Glycoursodeoxycholate	9.7
Yangonin	9.5
GW 4064	9.4
Lithocholic acid	9.2
2-nonynoic acid	9.1
Glycodeoxycholate	9.1
Taurochenodeoxycholate	9.1
taurolithocholate 3-sulfate	9.0
6-ECDCA	8.9