Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0008370 (cholestasis)
9,378 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
alkaline phosphatase 657
Sep 580
alanine aminotransferase 250
bile salt export pump 217
aspartate aminotransferase 210
Mol 210
albumin 165
ICP 160
farnesoid X receptor 139
ABCB11 133
collagen 128
She 124
Alagille syndrome 122
BSEP 121
ATP 110
gamma-glutamyl transpeptidase 110
endoplasmic reticulum 99
gut 96
microsomal 95
cytokine 94
more...
Disease
cholestasis 9378
liver disease 1276
cirrhosis 1052
hepatitis 825
pruritus 702
cholangitis 627
primary biliary cirrhosis 532
biliary atresia 381
cancer 363
biliary obstruction 343
gallstones 301
obstructive jaundice 289
sepsis 285
primary sclerosing cholangitis 284
tumor 272
sepsis 272
hyperbilirubinemia 261
viral hepatitis 236
pancreatitis 215
portal hypertension 211
more...
Symptom
abdominal pain 195
hepatomegaly 175
pain 138
diarrhea 100
fatigue 100
vomiting 86
splenomegaly 69
hepatosplenomegaly 59
anorexia 49
anesthesia 46
nausea 43
hyperemesis gravidarum 30
dark urine 29
seizures 25
Ill 24
regurgitation 24
respiratory distress 24
weakness 20
epigastric pain 19
asthenia 18
more...
Drug
vitamin E 60
Dermatol 52
Portal 33
PTC 20
NADH 19
ABC 15
lactose 14
EE2 13
lysine 11
ampicillin 11
Vitamin K 11
ROS 11
ascorbate 10
Vitamin E 10
Cardiovasc 10
Troglitazone 9
Estrogens 9
Monit 9
Leaf 8
caffeine 8
more...
Enzyme
alkaline phosphatase 658
alanine aminotransferase 426
gamma-glutamyl transpeptidase 349
aspartate aminotransferase 302
AST 89
ATPase 77
lactate dehydrogenase 65
catalase 52
peroxidase 50
superoxide dismutase 44
mitogen-activated protein kinase 43
CYP7A1 38
P-glycoprotein 37
5'-nucleotidase 30
glutathione peroxidase 27
UDP-glucuronosyltransferase 25
protein kinase C 24
transpeptidase 24
caspase-3 22
luciferase 22
more...
Compound
Clin 987
Dec 565
salt 312
sodium 239
DNA 182
Ursodeoxycholic acid 153
glucose 147
calcium 139
water 128
copper 125
ATP 110
oxygen 90
GSH 81
GSH 81
iron 77
sulfate 72
methionine 70
nitric oxide 67
Estrogen 63
creatinine 59
more...