Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0008325 (cholecystitis)
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Human Gene/Protein
PAPOLA 10.1
IL30 9.6
MPZL1 9.5
CPSF1 9.3
RSU-1 8.6
Macrosialin 8.6
KAS I 7.8
receptor-binding cancer antigen expressed on SiSo cells 7.7
EPT 7.6
SERPINB3 7.4
CP-2 7.3
IL-12A 6.8
Calpain-1 6.8
GDA 6.8
RCAS1 6.6
SCP2 6.3
N33 6.3
EBI3 6.3
biliary glycoprotein 6.2
KLK1 6.2
IL12A 6.2
PG synthetase 6.2
ELC 6.2
Nectin-4 6.1
lysophospholipase 6.1
SHF 6.0
cytosolic malate dehydrogenase 6.0
DPR 6.0
LHA 5.9
hydroxymethylbilane synthase 5.9
IL-12B 5.9
IDA 5.9
TPN 5.9
CPZ 5.8
profilin 1 5.7
ABCA1 protein 5.7
HOXB4 5.7
NPO 5.7
macrophage derived 5.6
PGIS 5.6
motilin receptor 5.6
CBD 5.5
glucose transporter 3 5.4
ABO blood type 5.4
UND 5.4
ACG 5.3
keratin 19 5.3
HM-1 5.3
cholecystokinin 5.3
B2R 5.3
CYBB 5.2
adipophilin 5.2
ARD 5.2
A30 5.1
prostate stem cell antigen 5.1
CPX 5.1
DNT 5.1
HBD 5.0
protoporphyrinogen oxidase 5.0
High-mobility group box 1 5.0
STG 5.0
Factor XII 5.0
DAPK 4.9
B and T lymphocyte attenuator 4.9
BSEP 4.9
Wnt inhibitory factor-1 4.9
S100A10 4.8
SSTR5 4.8
PBG 4.8
intestinal mucin 4.7
partial protein 4.7
REL 4.7
HLA-A24 4.7
ALC 4.6
factor XII 4.6
OPD 4.6
white cell 4.5
GGT 4.4
Hrs 4.4
LCT 4.4
more...
Disease
Pericholecystic abscess 13.1
Acute and chronic cholecystitis 13.1
Omental abscess 13.1
Gallbladder Carcinoma 13.1
cholecystectasia 13.1
cholecystitis 13.1
Emphysematous cholecystitis 12.5
Acalculous cholecystitis 12.4
Gangrenous cholecystitis 12.3
Gallbladder infection 12.1
Xanthogranulomatous cholecystitis 12.1
Courvoisier's gallbladder 12.1
Acute gangrenous cholecystitis 12.1
gallbladder abscess 12.1
Atypical appendicitis 12.1
Alcohol-induced chronic pancreatitis 12.1
Acute acalculous cholecystitis 12.1
Cholecystitis and cholelithiasis 11.9
Calculous cholecystitis 11.8
recurrent cholecystitis 11.7
gallbladder empyema 11.3
Rokitansky-Aschoff sinuses 11.2
Suppurative cholangitis 11.1
choledochitis 11.1
Diabetic gastropathy 11.1
gallbladder gangrene 11.1
pyometrium 11.1
chronic cholecystitis 11.0
acute cholecystitis 10.9
Biliary tract infection 10.9
Porcelain gallbladder 10.8
Intractable vomiting 10.8
Omental infarction 10.8
Gallbladder adenomyomatosis 10.8
Biliary colic 10.8
Gallbladder disease 10.3
head neoplasm 10.3
AIDS cholangiopathy 10.3
Cotton wool spots 10.3
C1 esterase deficiency 10.3
cholesterolosis 10.3
biliary colic 10.2
Bile peritonitis 10.2
Biliary sludge 10.0
Acute cholangitis 10.0
Abdominal sepsis 10.0
peri-rectal abscess 9.9
Gallbladder sludge 9.9
intrahepatic gallbladder 9.8
Mirizzi syndrome 9.7
Biliary disease 9.6
Epiploic appendagitis 9.6
gallbladder neoplasm 9.6
Radiation-induced liver disease 9.6
Endotoxicosis 9.6
unresectable gallbladder cancer 9.5
Biloma 9.5
gallbladder polyp 9.5
Gallstone ileus 9.5
biliary neoplasm 9.4
genitourinary disorder 9.4
gallstones 9.3
Extrahepatic cholestasis 9.2
Secondary sclerosing cholangitis 9.2
Hemobilia 9.2
choledocholithiasis 9.2
biliary tract disease 9.2
cholecystolithiasis 9.1
postcholecystectomy syndrome 9.1
Microlithiasis 8.9
cholemia 8.9
Unconjugated hyperbilirubinemia 8.8
Oriental cholangiohepatitis 8.8
cholangitis 8.8
gallbladder cancer 8.8
Conjugated hyperbilirubinemia 8.8
omentitis 8.8
adenocarcinoma of the gallbladder 8.8
Hemolytic disease 8.7
Cholesterol gallstones 8.7
more...
Symptom
Murphy's sign 11.8
Courvoisier's sign 10.8
Pneumobilia 10.8
liver pain 10.1
right upper quadrant pain 10.1
localized abdominal pain 9.9
decreased bowel sounds 9.6
abdominal rigidity 9.1
Mucosal hyperplasia 8.8
Upper abdominal pain 8.8
intestinal pain 8.5
generalized abdominal pain 8.5
Pain and tenderness 8.0
acute abdominal pain 7.8
acute abdomen 7.6
Referred pain 7.3
left upper quadrant pain 7.0
intestinal angina 7.0
epigastric pain 6.9
iliac fossa pain 6.8
No adverse effect 6.7
abdominal pain 6.7
dark urine 6.5
Visceral pain 6.2
Crushing 6.1
generalized rash 5.9
Gastrointestinal symptoms 5.9
right lower quadrant pain 5.8
jaw pain 5.6
rectal pain 5.5
colic 5.4
hepatomegaly 5.2
Multimorbidity 5.2
vomiting 4.9
non-productive cough 4.9
lassitude 4.9
fever of unknown origin 4.9
hyperemesis 4.8
nausea 4.8
hypoproteinemia 4.5
chills 4.5
sore throat 4.5
intestinal bleeding 4.4
renal colic 4.4
rigors 4.4
abdominal fullness 4.4
belching 4.4
bloating 4.4
lethargy 4.2
tenesmus 4.2
nausea and vomiting 4.1
emaciation 4.0
abdominal cramps 4.0
hyperemesis gravidarum 4.0
hepatosplenomegaly 4.0
abdominal discomfort 3.9
excessive sweating 3.9
decreased appetite 3.9
splenomegaly 3.8
hypertonia 3.8
anorexia 3.8
constipation 3.8
acute pain 3.7
myalgia 3.6
flank pain 3.6
diarrhea 3.5
livedo 3.3
Ill 3.3
Wind 3.3
asthenia 3.3
shoulder pain 3.2
hot flashes 3.0
Postoperative pain 3.0
paresis 2.9
pain 2.9
dysarthria 2.8
chronic constipation 2.7
photophobia 2.4
discomfort 2.3
ENT 2.3
more...
Drug
Sisomicin sulfate 13.1
Oragrafin calcium 13.1
Trepibutone 12.1
Sincalide 9.6
Cilastatin 7.6
Ovulen 7.5
CXM 7.4
LVFX 7.2
Sonazoid 6.7
Treprostinil 6.6
Gd-BOPTA 6.3
Lipiodol 6.0
CPZ 5.8
SBT 5.5
Bactrim 5.4
Talc 5.3
AmBisome 5.1
Mezlocillin 5.0
IPD 4.9
Gemfibrozil 4.7
Cisapride 4.7
Artesunate 4.7
Eculizumab 4.6
Limonene 4.6
Zinat 4.5
Trimethoprim-sulfamethoxazole 4.5
Hydrochlorothiazide 4.5
Lugol 4.4
Cilostazol 4.4
Ezetimibe 4.3
Gastro 4.3
CVA 4.2
Emodin 4.2
IPM 4.1
Piperacillin 4.1
Emodin 3.9
PTC 3.9
Everolimus 3.6
Indomethacin 3.6
Gelfoam 3.6
Atropine 3.4
Prednisone 3.1
Ketoconazole 3.0
Portal 3.0
Doxycycline 3.0
Azithromycin 2.8
Serum albumin 2.8
Fraction 2.7
NBT 2.7
Lovastatin 2.7
IL-1ra 2.7
ampicillin 2.6
Sorafenib 2.5
Cimetidine 2.4
Cimetidine 2.4
ENT 2.3
niacin 2.2
Propofol 2.0
Dakar 2.0
NAG 2.0
Paraffin 2.0
Estrogens 1.9
ROC 1.7
Histamine 1.6
Alanine 1.6
ALA 1.6
MOF 1.5
AZT 1.5
ABC 1.0
nitroglycerin 1.0
Adriamycin 0.9
CAM 0.6
PTH 0.3
Dial 0.2
EE2 0.1
Cardiovasc -0.1
caffeine -0.3
Leaf -0.3
Asthma -0.6
MAP -0.9
more...
Enzyme
EPT 7.2
beta-D-fucosidase 7.1
prostacyclin synthase 5.5
acyl carrier protein synthase 5.4
condensing enzyme 5.0
neuropathy target esterase 5.0
protoporphyrinogen oxidase 4.8
beta-xylosidase 4.4
phospholipase A1 4.4
gamma-glutamyl transpeptidase 4.1
prostaglandin synthetase 3.8
arylsulfatase A 3.8
porphobilinogen deaminase 3.8
mu-calpain 3.7
E-2 3.6
alanine aminotransferase 3.6
insulin-degrading enzyme 3.6
TACE 3.4
BAT 3.4
alkaline phosphatase 3.3
AST 3.3
aspartate aminotransferase 3.3
phosphorylase kinase 3.3
BIS 3.2
urease 2.8
urease 2.8
tryptase 2.6
3-hydroxy-3-methylglutaryl coenzyme A reductase 2.6
beta-glucuronidase 2.5
phospholipase A2 2.4
CPT 2.4
dipeptidyl peptidase IV 2.4
DTA 2.4
CPT 2.3
alpha-amylase 2.3
kallikrein 2.1
beta-lactamase 2.0
CPT 1.9
lipase 1.9
ceruloplasmin 1.8
BMT 1.7
asparaginase 1.7
diaphorase 1.6
beta-glucosidase 1.6
sulfatase 1.4
CD10 1.4
beta-glucosidase 1.4
lysozyme 1.3
enolase 1.2
arginase 1.2
cathepsin B 1.1
chitinase 1.0
acid phosphatase 1.0
glutamate dehydrogenase 1.0
glutamate dehydrogenase 1.0
aldehyde dehydrogenase 1.0
aldehyde dehydrogenase 1.0
PAH 1.0
thromboplastin 1.0
glutamate dehydrogenase 1.0
aldehyde dehydrogenase 1.0
citrate synthase 0.9
hyaluronidase 0.9
transcriptase 0.9
transglutaminase 0.8
aldehyde dehydrogenase 0.7
hyaluronidase 0.5
cholinesterase 0.4
aldehyde dehydrogenase 0.4
papain 0.4
prostate-specific antigen 0.3
peroxidase 0.2
xanthine oxidase 0.0
lipoxygenase -0.0
plasmin -0.1
tyrosinase -0.1
catalase -0.1
creatine kinase -0.1
glutathione reductase -0.1
NADPH oxidase -0.3
more...
Compound
Milibis 13.1
N-allylurea 10.8
Iodoquinol 9.6
Taurodeoxycholic acid 8.8
X 14 8.0
Cilastatin 7.6
Cholestanol 7.6
Telepaque 7.3
4-Methylumbelliferone 7.1
PGB2 6.6
phenylarsonic acid 6.2
Mezlocillin 6.2
Brilliant Green 6.2
Cefotetan 6.2
Tazobactam 6.2
M 3 5.9
IDA 5.8
VM-26 5.7
EDAP 5.6
FUDR 5.6
CPZ 5.6
Ceftriaxone 5.5
Ursodeoxycholic acid 5.4
A 71 5.3
Metoclopramide 5.2
PBG 5.2
Moxalactam 5.1
PALA 5.0
Cystathionine 4.9
IPD 4.9
Cystathionine 4.9
phenyl acetate 4.9
Loperamide 4.8
Bismuth 4.8
Phenylbutazone 4.8
Cholic acid 4.7
Cisapride 4.7
6-Hydroxydopamine 4.7
Cefazolin 4.7
M 2 4.6
Aztreonam 4.6
Limonene 4.5
CPB 4.4
HfO2 4.4
2,4-DNT 4.3
prostaglandin F1 4.3
Sulfasalazine 4.3
DHF 4.2
Imipenem 4.2
Emodin 4.2
Piperacillin 4.1
MPT 4.1
Sulfamethoxazole 4.0
A 42 3.9
GPT 3.8
Bilirubin 3.8
Fenofibrate 3.8
Cefotaxime 3.8
Indomethacin 3.8
Tempol 3.8
Hydrochlorothiazide 3.8
Amitriptyline 3.7
Albendazole 3.7
Cystine 3.7
Praziquantel 3.6
Lovastatin 3.6
Chlorpromazine 3.6
Voriconazole 3.5
Sorbitol 3.5
Linezolid 3.4
TACE 3.4
Propranolol 3.4
Atropine 3.4
Ether 3.4
Propranolol 3.4
DSS 3.3
Ether 3.3
Tumor Necrosis Factor 3.3
MIT 3.3
MIT 3.3
more...