Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0008325 (cholecystitis)
 3,686 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The renal function was investigated in 209 patients with the pancreato-biliary pathology. The investigation was carried out dynamically prior to and after the operation. All patients showed functional changes in the kidneys being aggravated in the postoperative period. The concentration and nitrogen excretion functions, the renal function of electrolyte metabolism and maintenance of the acid-base balance were found to be mostly impaired. These changes proved to be the least pronounced in calculous cholecystitis and mostly pronounced in mechanic jaundice. Recognition of early disorders in the renal function may prevent the development of hepato-renal insufficiency, which is one of the main causes of postoperative mortality in patients with the pancreato-biliary pathology.
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PMID:[Diagnosis of early disorders of kidney function in lesions of the pancreato-biliary system]. 122 14

Large burn patients make up a subgroup of critical patients in whom the nutro-metabolic support reaches its maximum importance, due to the fact thermal aggression induces a hypermetabolic response which is prolonged until the wounds heal. In fact, there are few deubt with regard to the importance of nutritional support tin the management of these patients for reducing the complications and facilitating the closing of the wounds and the recovery of the patients. Thermal trauma induces the release of counter-regulatory hormones and of other mediators which favor proteineic catabolism, mainly muscular, lipolysis, and gluconeogenesis; as well, there is an alteration of thermoregulation, raising the equilibrium point. The estimate of the energetic requirements may be done by means of predictive equations, although these tend to over-estimate it; indirect calorimetry is the most exact method and this permits monitorization of the evolution, which is very variable in time, it gives the metabolic response to the thermal aggression, at the same time as permitting the analysis of the use of the administrated substrates. Its use has meant a dramatic decrease in the supply of calories administered to burn patients, with the present recommendation being 35-40 kcal/kg/d. The supply of non-proteineic calories has also been modified: It is recommended that at least 60-70% of the calories administered, be in the form of carbohydrates, without surpassing 1600 kcal/kg/d. The optimal relation of non-proteineic kcal:nitrogen, is 150:1. The administration route of the artificial nutrition support should be individualized in each patient, with the enteral route being the route of choice, as this is the most physiologic, the cheapest, and the safest; its use prevents the appearance of certain complications (Curling ulcer, cholecystitis, bacterial translocation); however, if his does not cover nutritional requirements of the burn patient, parenteral nutrition should be associated to this.
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PMID:[Nutritional support for the large burn patient]. 961 72

A patient with bronchial asthma developed cholecystitis. Laboratory investigations revealed marked eosinophilia (6,615/mm3), an elevated anti-neutrophil cytoplasmic antibody level and renal dysfunction (blood urea nitrogen 14 mg/dl, creatinine 1.4 mg/dl). Following cholecystectomy, histopathological examination revealed a marked inflammatory cell infiltrate composed mainly of eosinophils with evidence of invasion of the wall of the gall bladder and granuloma formation of arterioles. A diagnosis of Churg-Strauss syndrome was made and she was treated with 60 mg of prednisolone per day. A renal biopsy was performed one year later in view of persistent renal dysfunction. Pathological analysis revealed a pauci-immune glomerulonephritis with interstitial changes but no crescent formation.
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PMID:Churg-strauss syndrome with cholecystitis and renal involvement. 1451 84