Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0008325 (cholecystitis)
 3,686 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A case with prolonged bacterial infection accompanied by an abnormal serum protein which migrated in the post-gamma region on electrophoresis is presented. The abnormal protein was identified as IgG with gamma-type light chain moiety. The patient suffered from prolonged pneumonia and cholecystitis, Bone marrow aspiration and skeletal x-rays did not indicate multiple myeloma.
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PMID:An extremely basic monoclonal IgG in an aged apoplectic patient with prolonged bacterial infection. 13 72

Changes in serum protein levels are produced by oral contraceptives. They reflect hepatic synthesis of proteins. Changes range from a 40% decrease in orosomucoid to an 180% increase in ceruloplasmin. Alterations in the concentration of some globulin proteins lead to altered serum levels of some hormones and trace metals. Plasma levels of cortisol and thyroxine are most affected. An estrogen-induced increase in thyroxine-binding globulin causes a transient reduction in free thyroxine (T4). This results in a compensatory increase in thyroid-stimulating hormone. The net effect is an unchanged concentration of T4 and the patient may be reported as euthyr id. Increases in renin substrate with rise in renin activity, angiotensin 2, and aldosterone, may be related to the development of hypertension in some women. Oral contraceptives may cause significant increases in some lipids. Elevations in cholesterol and nonesterified fatty acids are less changed. The drug-induced changes can complicate a definite diagnosis of hyperlipidemia. The glucose tolerance curve in users of oral contraceptives may simulate the diabetic type. Hepatic function tests may suggest hepatic damage. There is a higher incidence of cholecystitis and gallstones in women using oral contraceptives. Blood coagulation tests may be modified. Drug interference from oral contraceptive use must be considered in interpreting laboratory reports.
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PMID:Drug interference with laboratory tests: oral contraceptives. 1226 Jan 55

Portal vein thrombosis is a rare complication accompanied with acute pancreatitis or cholangitis/cholecystitis. The main pathogenesis of portal vein thrombosis in pancreatitis or cholangitis/cholecystitis are suggested to be venous compression by pseudocyst and an imbalance between the blood coagulation and fibrinolysis. In this case report, we experienced a 63 year old male who developed portal vein thrombosis later in the course of the treatment of acute gallstone pancreatitis with cholangitis/cholecystitis without any symptom or sign. The diagnosis of portal vein thrombosis was given on follow up CT scan and serum protein S activity was decreased to 27% in laboratory study. Immediate anticoagulation therapy with heparin and thrombolytic therapy with urokinase and balloon dilatation were performed. Despite the aggressive treatment, complete reperfusion could not be obtained. With oral warfarin anticoagulation, the patient showed no disease progression and was discharged. We report a case of portal vein thrombosis as a complication of acute pancreatitis and cholangitis/cholecystitis with a review of literatures.
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PMID:[A case of portal vein thrombosis associated with acute pancreatitis and cholangitis]. 1603 Apr 6