Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0008325 (cholecystitis)
 3,686 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Gastroenteritis due to Salmonella enteritis is an endemic disease in our region, extraintestinal manifestations however are rare. We report a 8 years old girl who presented after 4 days of an unspecific diarrheal disease with watery liquid stools, vomiting, abdominal cramps, fever above 39 Grad C and symptoms and signs of an acute abdominal emergency. Mid abdominal laparotomy disclosed a cholecystitis with reactive peritonitis. Cultures of bile showed Salmonella group B as the causative organism. Cholecystectomy was performed, postoperatively Gentamycin later Chloramphenicol was administered. The postoperative course was unremarkable. Cholecystitis is a rare disease in pediatrics. Gallstones don't seem to play a roll in the etiology unlike in adults. It usually follow serious systemic infections or postoperatively after unrelated abdominal surgery due to overgrowth of the biliary system and organisms contaminating the upper gastrointestinal tract (biliary stasis, dehydration). Salmonella enteritidis as a cause of a cholecystitis is a rare event.
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PMID:[Salmonella-cholecystitis (author's transl)]. 53 Jul 33

Eleven of 20 patients with chronic granulomatous disease (55%) developed serious gastrointestinal complications requiring surgical consultation or operation over a 10-year period with an average of 2.2 complications per patient. The mean age of onset of symptoms was 12 years (range 2.5 months to 25 years), and 91% of the patients were male. Admission for gastrointestinal complications constituted 18% of all admissions for these patients; the mean hospitalization time was 27.8 +/- 3.5 (SEM) days. Hepatic abscess, the most common complication, occurred in 16 instances. Perirectal abscess developed in three patients and gastric outlet obstruction developed in two patients. Other complications included appendicitis, acalculous cholecystitis, and Salmonella enteritis. Open hepatic debridement and external drainage combined with long-term intravenous antibiotics (mean 25.2 +/- 4.8 days) were curative in every case, but operative morbidity was frequent and severe. Twelve major complications accompanied open hepatic drainage in 14 cases including wound disruption, prolonged febrile course, subhepatic abscess, and recurrent hepatic abscess. Five secondary operations were required for treatment of these complications. Gastric outlet obstruction, by contrast, was successfully managed nonoperatively. Staphylococcus aureus was an etiologic agent in 66% of the cases, but many other aerobic gram-positive and gram-negative organisms were isolated. Anaerobic bacteria were unusual. Bacteremia occurred only once.
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PMID:Gastrointestinal complications of chronic granulomatous disease: surgical implications. 662 57