Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0008325 (cholecystitis)
 3,686 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Computed tomography (CT) was used to study 79 patients with suspected gallbladder disease. First and second generation scanners were used to determine the efficacy of CT in detecting cholecystitis or cholelithiasis. Manifestations of gallbladder disease such as hydrops, opaque and nonopaque gallstones, chronic cholecystitis with thickened inflammatory walls, and secondary liver abscesses can be easily detected. It is a useful technique for individuals in whom the gallbladder has failed to opacity on oral cholecystography. The scanning method is described, and estimates of reliability are given including its accuracy, limitations, and place in the management of gallbladder disease, especially cholelithiasis. When conventional radiographic examinations or ultrasound fail to give definitive diagnostic information, CT can be a useful alternative with an overall diagnostic accuracy greater than 80%.
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PMID:Computed tomography of the gallbladder. 41 41

The amount of free and acetylated norsulfazol in the urine of patients with gastrointestinal diseases was analysed 3 hours after peroral administration of the drug (20 mg/kg). The acetylation rate of norsulfazol in patients of 21--30 years of age was significantly lower than that in heathy subjects of the same age. In groups of 31--40, 41--50 and 51--60 years of age the acetylation rate was 47, 42 and 43%, respectively. In patients with chronic cholecystitis excretion with urine of free norsulfazol was 2-fold as increased whereas in chronic gastritis there was a 2.7-fold increase as compared to controls. The acetylation rate of norsulfazole was 1.6, 1.4 and 1.5-fold reduced in duodenal ulcer, cholecystitis and gastritis, respectively.
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PMID:[Acetylation and urinary excretion of norsulfazole in gastrointestinal disease patients of different age groups]. 48 30

The purpose of this investigation was to determine the diagnostic value (validity) of technetium-99m-pyridoxylideneglutamate cholescintigraphy (99mTc-PGC) in patients with and without cholecystitis and to compare its validity to those of oral cholecystography (OC) and ultrasonography (US). 99mTc-PGC was applied to 50 patients with acute, subacute, and/or chronic cholecystitis with cystic duct obstruction proven histologically and operatively, and also to 27 non-diseased volunteers and 43 patients with right upper quadrant abdominal pain who subsequently were proven free of gallbladder disease. In addition, 38 patients had OC, and 31 had US performed. The results shows that the sensitivity and specificity of 99mTc-PGC were 100%. Whereas for OC the sensitivity was 87%, specificity was 100%. For US the sensitivity was 70%, and specificity was 93%. The repeatability of 99mTc-PGC, OC, and US were 100%, 97% and 81% respectively. These data show that 99mTc-pyridoxylideneglutamate cholescintigraphy is a valid diagnostic tool in the evaluation of patients with cholecystitis, and is also safe and simple.
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PMID:The validity of 99mTc-pyridoxylideneglutamate (P.G.) cholescintigraphy as a diagnostic test for cholecystitis. 65 80

A comparative analysis of postoperative lethality in acute and chronic cholecystitis, acute appendicitis and cancer of the stomach together with the results of biochemical and morphological studies of the liver are covered here. A direct correlation of postoperative lethality in cholecystitis with the presence and stage of concomitant cholangiohepatitis has been found.
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PMID:[Aanalysis of the causes of high lethality in the surgical treatment of acute cholecystitis]. 71 44

Cholescintigraphy was performed in 113 patients of whom 38 had normal gallbladders, 37 had acute cholecystitis and 38 had chronic cholecystitis. The radiopharmaceuticals used in the study were either 99mTc-dimethyl acetanilide iminodiacetic acid or 99mTc-paraisopropyl acetanilide iminodiacetic acid, both of which performed equally well. All patients with non-visualized gallbladders had cholecystitis, but visualization did not exclude disease. The rapidity of obtaining the results (within one hour), the complete absence of untoward reactions to the radiopharmaceuticals, the much lower frequency of subtle or indeterminate results, the ability to render useful information in the presence of moderate jaundice and the lack of interference from overlying intestinal contents establishes these radionuclide agents as superior to both radiographic oral and intravenous cholangiography in the investigation of the acute abdomen.
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PMID:Assessment of the utility of gallbladder imaging with 99mTc-IDA. 72 28

There is a definite clinical entity of chronic acalculous cholecystitis that can be cured by cholecystectomy. More research needs to be done on how this condition could be more accurately and earlier diagnosed. The majority of chronic gallbladder symptoms are not dependent on the presence of calculi. Gallbladder x-ray films are subject to significant diagnostic error, as are all other diagnostic tests. There is a need for more uniformity among pathologists as to what microscopic findings substantiate a diagnosis of chronic cholecystitis.
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PMID:The acalculous gallbladder. 83 88

Gallium has been shown to accumulate in metabolically active tissue including sites of infection. The purpose of this study was to evaluate gallium scanning in cholecystitis. Ten patients with cholecystitis were studied using conventional gallium scanning techniques. Five patients with acute cholecystitis showed intense gallium accumulation in the gallbladder area. One of five patients with chronic cholecystitis showed significant accumulation in the gallbladder. The limitations of this method are mainly the need for serial scanning to rule out gallium accumulation in the hepatic flexure of the colon and also the failure to detect consistently a chronically diseased fibrotic gallbladder. We conclude that gallium scanning of the gallbladder is an important adjunctive study in the evaluation of cholecystitis.
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PMID:Gallium gallbladder scanning in cholecystitis. 111 Apr 20

Thirty patients (22 male, 8 female, age range 25-83) with gallbladder (GB) masses or thickened GB wall found by real-time sonography were studied by duplex and color doppler ultrasonography. All the patients were confirmed pathologically after surgery. Seven of 8 patients with primary GB malignancy (adenocarcinoma 7, malignant fibrous histiocytoma 1) showed high velocity arterial blood flow signal (VABFS) in the tumor masses. No VABFS was observed in 10 patients (metastatic adenocarcinoma 3, adenoma 5, polyps 2). All the 10 patients with primary GB carcinoma (masses 8, wall thickening 2) showed high VABFS in the GB wall. In contrast, no VABFS was found in the GB wall in 3 patients with metastatic GB carcinoma. In 17 patients with benign GB lesion (adenoma 5, polyps 2, xanthogranuloma 2, chronic cholecystitis 6, subacute cholecystitis 2), only 5 (polyps 1, xanthogranuloma 1, chronic cholecystitis 1, subacute cholecystitis 2) demonstrated low VABFS. High VABFS in the GB masses or GB wall, a significant feature of primary GB carcinoma, is helpful in differentiating primary GB carcinoma from metastatic and benign GB lesion.
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PMID:[Color Doppler flow imaging in gallbladder tumors]. 133 Feb 26

Duodenogastric reflux (DGR) as seen on hepatobiliary scintigraphy has been reported as a useful secondary sign for the diagnosis of acute cholecystitis. We evaluated the association of reflux with cases of acute cholecystitis as compared to those with chronic cholecystitis or other conditions. Thirty-six of 198 patients referred for hepatobiliary imaging showed DGR (18%). Among 26 patients with acute cholecystitis, 6 (23%) had DGR as compared to 9/40 (23%) cases with chronic cholecystitis, 3/12 cases with acute pancreatitis, 4/13 cases with previous cholecystectomy, and 3/8 cases with duodenal ulcer. No statistically significant differences were found between the prevalence of DGR in cases with acute cholecystitis and those with chronic cholecystitis or other nonacute cholecystitis diagnostic categories. Although acute cholecystitis is a condition frequently associated with DGR, such reflux is a nonspecific finding and should not be considered as a secondary sign of acute cholecystitis when interpreting hepatobiliary scans.
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PMID:Scintigraphic evaluation of duodenogastric reflux: significance in the diagnosis of acute cholecystitis. 134 21

Results are reported of a study of the effect of benzohexonium electrophoresis on the epigastric area in cardiac syndrome due to chronic noncalculous cholecystitis in 72 patients. This treatment produced a favourable effect in reflex stenocardia as confirmed by data of clinical and paraclinical findings. The authors recommended to include benzohexonium electrophoresis in patients with the biliary cardiac syndrome in the complex treatment of patients with chronic cholecystitis.
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PMID:[The pharmacological correction of reflex stenocardia due to chronic noncalculous cholecystitis]. 136 27


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