Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0008272 (chlorosis)
 2,195 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Melatonin has recently been demonstrated to play important roles in the regulation of plant growth, development, and abiotic and biotic stress responses. However, the possible involvement of melatonin in Fe deficiency responses and the underlying mechanisms remained elusive in Arabidopsis thaliana. In this study, Fe deficiency quickly induced melatonin synthesis in Arabidopsis plants. Exogenous melatonin significantly increased the soluble Fe content of shoots and roots, and decreased the levels of root cell wall Fe bound to pectin and hemicellulose, thus alleviating Fe deficiency-induced chlorosis. Intriguingly, melatonin treatments induced a significant increase of nitric oxide (NO) accumulation in roots of Fe-deficient plants, but not in those of polyamine-deficient (adc2-1 and d-arginine-treated) plants. Moreover, the melatonin-alleviated leaf chlorosis was blocked in the polyamine- and NO-deficient (nia1nia2noa1 and c-PTIO-treated) plants, and the melatonin-induced Fe remobilization was largely inhibited. In addition, the expression of some Fe acquisition-related genes, including FIT1, FRO2, and IRT1 were significantly up-regulated by melatonin treatments, whereas the enhanced expression of these genes was obviously suppressed in the polyamine- and NO-deficient plants. Collectively, our results provide evidence to support the view that melatonin can increase the tolerance of plants to Fe deficiency in a process dependent on the polyamine-induced NO production under Fe-deficient conditions.
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PMID:Exogenous Melatonin Improves Plant Iron Deficiency Tolerance via Increased Accumulation of Polyamine-Mediated Nitric Oxide. 2779 44

Waterlogging, one of the notorious abiotic stressors, retards the growth of apple plants and reduces their production. Thus, it is an urgent agenda for scientists to identify the suitable remedies for this problem. In the current study, we found that melatonin significantly improved the tolerance of apple seedlings against waterlogging stress. This was indicated by the reduced chlorosis and wilting of the seedlings after melatonin applications either by leaf spray or root irrigation. The mechanisms involve in that melatonin functions to maintain aerobic respiration, preserves photosynthesis and reduces oxidative damage of the plants which are under waterlogging stress. Melatonin application also enhances the gene expression of its synthetic enzymes (MbT5H1, MbAANAT3, MbASMT9) and increases melatonin production. This is the first report of a positive feedback that exogenous melatonin application promotes the melatonin synthesis in plants. A post-transcriptional regulation apparently participated in this regulation. When exogenous melatonin meets the requirement of the plants it is found that the protein synthesis of MbASMT9 was suppressed. Taken together, the results showed that melatonin was an effective molecule to protect plant, particularly apple plant, against waterlogging stress.
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PMID:Melatonin Improves Waterlogging Tolerance of Malus baccata (Linn.) Borkh. Seedlings by Maintaining Aerobic Respiration, Photosynthesis and ROS Migration. 2842 30

The manuscript presents an elaborate report on the ameliorative effects of exogenous melatonin in soil-grown seedlings of the rice variety, IR-64 subjected to prolonged fluoride stress. Exogenous melatonin stimulated the physiological growth of the stressed seedlings by triggering high accumulation of gibberellic acid (GA) and melatonin via up regulation of the biosynthetic genes like GA3ox, TDC, SNAT and ASMT. The endogenous abscisic acid (ABA) content increased via induction of NCED3 and suppression of ABA8ox1. However, the ABA-dependent genes like TRAB1, WRKY71 and OSBZ8 were down regulated in presence of high endogenous GA and melatonin. High melatonin level led to low indole-3-acetic acid accumulation in the treated seedlings during fluoride stress. Melatonin significantly decreased fluoride bioaccumulation by suppressing its uptake via CLC1 and CLC2, and also restored P-H+/ATPase expression. The damage indices like chlorosis (accompanied by low RuBisCo), malondialdehyde, electrolyte leakage, methylglyoxal (detoxified by glyoxalase II) and protein carbonylation were greatly reduced. Increased proline synthesis, activation of the ascorbate-glutathione cycle and enhanced activity of glutathione peroxidase, catalase and guaiacol peroxidase led to low ROS accumulation and localization in the melatonin-treated plants exposed to stress. Overall, melatonin treatment alleviated fluoride-mediated injuries by restricting fluoride uptake, refining the defence machinery and altering the phytohormone homeostasis.
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PMID:Melatonin application reduces fluoride uptake and toxicity in rice seedlings by altering abscisic acid, gibberellin, auxin and antioxidant homeostasis. 3169 29