Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0007222 (cardiovascular disease)
65,817 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
insulin 6174
Sep 4147
HDL 2443
C-reactive protein 1949
Mol 1810
renin 1199
fibrinogen 868
albumin 756
hemoglobin 741
cytokine 726
angiotensin II 654
gut 638
adiponectin 630
collagen 532
leptin 520
IL-6 499
tumor necrosis factor 462
TNF 450
apolipoprotein 427
CRP 424
interleukin-6 414
Lp(a) 393
nitric oxide synthase 393
apolipoprotein B 386
LDL receptor 359
Ang II 336
ACE 335
ATP 331
vascular endothelium 326
natriuretic peptide 323
Men 313
plasminogen activator inhibitor-1 311
angiotensin receptor 307
superoxide dismutase 305
calcium channel 298
endothelial nitric oxide synthase 285
reductase 278
chronic renal failure 272
glucagon 257
thrombin 251
more...
Disease
cardiovascular disease 65817
diabetes 13560
hypertension 12024
obesity 8296
atherosclerosis 7790
cancer 5998
type 2 diabetes 5277
stroke 4945
metabolic syndrome 3997
myocardial infarction 3782
heart failure 3361
dyslipidemia 2888
coronary heart disease 2878
coronary artery disease 2813
renal disease 2253
myocardial ischemia 1698
heart disease 1629
plaque 1422
hypercholesterolemia 1416
depression 1406
hyperlipidemia 1398
vascular disease 1227
osteoporosis 1154
hyperglycemia 1130
ischemia 901
glucose intolerance 886
HIV 879
congestive heart failure 842
acute myocardial infarction 819
Alzheimer's disease 816
chronic disease 813
breast cancer 783
ventricular hypertrophy 762
renal failure 741
chronic renal failure 655
rheumatoid arthritis 648
dementia 625
abdominal obesity 572
chronic obstructive pulmonary disease 560
cardiomyopathy 537
more...
Symptom
overweight 1590
angina 599
pain 383
fatigue 244
chest pain 219
anesthesia 179
dyspnea 161
menopausal symptoms 156
headache 125
sleepiness 117
insomnia 100
weakness 96
syncope 87
diarrhea 87
cough 82
seizures 81
collapse 77
snoring 72
discomfort 70
discomfort 67
exhaustion 64
nausea 63
respiratory distress 60
hot flushes 55
acute stress 53
hot flashes 52
cachexia 51
dizziness 49
flushing 46
myalgia 42
hunger 39
shortness of breath 37
starvation 37
constipation 37
vomiting 33
Depressive symptoms 33
stigma 31
spasm 30
thinning 29
functional recovery 29
more...
Drug
Cardiovasc 2666
vitamin E 376
Dial 336
ascorbate 286
niacin 223
EPA 150
ROS 148
Dermatol 146
Angiotensin II 130
Monit 127
lysine 103
caffeine 95
Vitamin E 81
Simvastatin 77
nitroglycerin 77
MAP 71
Nephron 64
ROC 52
Nephron 52
Rosuvastatin 51
Estrogens 49
Ramipril 47
PTH 47
Pravastatin 46
Ezetimibe 46
Glucagon 46
Clopidogrel 45
EE2 45
Leaf 40
SiO2 39
ADM 37
IL-2 34
Spectrum 34
Nitric Oxide 33
Albumin 32
Raloxifene 32
THF 30
ICI 29
BH4 29
Lovastatin 28
more...
Enzyme
renin 1199
ACE 575
mitogen-activated protein kinase 404
superoxide dismutase 365
thrombin 242
NO synthase 229
protein kinase 227
NADPH oxidase 226
catalase 214
ACS 208
ERK 197
NADPH oxidase 183
tissue plasminogen activator 182
AMP-activated protein kinase 174
peroxidase 174
glutathione peroxidase 164
lipoprotein lipase 156
alanine aminotransferase 148
protein kinase C 137
phosphodiesterase 127
methylenetetrahydrofolate reductase 126
methylenetetrahydrofolate reductase 125
luciferase 124
phospholipase A2 124
aspartate aminotransferase 118
caspase-3 113
focal adhesion kinase 109
CAD 107
CAD 107
CAD 107
paraoxonase 106
creatine kinase 102
paraoxonase 93
subtilisin 92
lactate dehydrogenase 92
proprotein convertase 89
AMPK 87
xanthine oxidase 84
lipase 84
calcineurin 82
more...
Compound
Clin 5663
glucose 5026
Dec 4290
Cardiol 3788
oxygen 1972
calcium 1867
nitric oxide 1477
DNA 1320
homocysteine 1166
sodium 1140
creatinine 936
water 853
vitamin D 782
Insulin 696
aldosterone 677
salt 639
phosphate 590
Cholesterol 543
acetate 530
arginine 466
TNF 450
potassium 431
iron 394
Dial 342
ATP 331
ethanol 314
methionine 294
ASA 289
nitrogen 280
Estrogen 276
hydrogen 272
Pac 263
sulfate 241
Angiotensin II 239
phosphorus 232
Estrogen 230
cysteine 225
Vitamin D 213
ACS 209
ACS 208
more...