Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0007131 (
non-small cell lung cancer
)
22,601
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
tyrosine kinase
2230
epidermal growth factor receptor
2203
EGFR
1683
Sep
1363
Mol
1183
p53
958
ALK
516
AKT
516
PD-L1
479
anaplastic lymphoma kinase
478
KRAS
459
TNM
455
PD-1
395
PI3K
369
caspase-3
367
MET
356
vascular endothelial growth factor
350
nodal
331
ERK
326
Bcl-2
325
more...
Disease
non-small cell lung cancer
22601
cancer
10559
tumor
8392
lung cancer
7825
adenocarcinoma
2462
lung carcinoma
1813
metastases
1376
small cell lung cancer
1213
squamous cell carcinoma
1140
tumor growth
1093
tumorigenesis
879
breast cancer
821
carcinoma
819
tumor progression
729
melanoma
658
neutropenia
535
carcinogenesis
532
brain metastases
448
primary tumor
350
colorectal cancer
346
more...
Symptom
diarrhea
292
nausea
237
vomiting
210
fatigue
196
pain
147
dyspnea
140
nausea and vomiting
127
anorexia
107
cough
103
hemoptysis
68
myalgia
43
chest pain
39
asthenia
39
headache
34
cachexia
33
constipation
32
starvation
32
shortness of breath
29
anesthesia
28
exhaustion
27
more...
Drug
Gefitinib
347
Erlotinib
220
Cardiovasc
217
Taxol
178
Pemetrexed
157
Docetaxel
155
ROS
130
Bevacizumab
103
Vinorelbine
102
Monit
77
CPT-11
70
ROC
67
Taxotere
61
Cetuximab
60
IL-2
53
lysine
52
Tarceva
49
GEO
47
Navelbine
44
CSF
40
more...
Enzyme
ERK
3099
mitogen-activated protein kinase
596
luciferase
374
caspase-3
282
focal adhesion kinase
268
MEK
226
protein kinase
178
PARP
175
caspase-9
104
proteasome
91
thymidylate synthase
88
topoisomerase
82
topoisomerase
77
protein kinase C
74
P-glycoprotein
73
reverse transcriptase
68
AMP-activated protein kinase
66
caspase-8
60
SPC
58
cdc2
57
more...
Compound
DNA
1716
Dec
1652
Clin
1541
TNM
454
methionine
431
MTT
400
tyrosine
350
DDP
328
oxygen
306
MEK
184
Paclitaxel
172
ATP
170
glucose
168
Gemcitabine
157
Gemcitabine
157
CBDCA
119
CBDCA
119
Docetaxel
118
water
96
serine
88
more...