Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0007097 (
carcinoma
)
152,788
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A novel antitumor antibiotic, methylenolactocin, was isolated from the culture filtrate of a new isolate of fungus identified as Penicillium sp. The fermentation yield reached about 100 mg per liter of the broth. Methylenolactocin has the molecular formula of
C11H16O4
and possess an exomethylene lactone structure. Its structure was determined to be 3-carboxy-2-methylene-4-nonanolide by spectroscopic data. It is active against some Gram-positive bacteria and it prolongs the life span of mice inoculated with Ehrlich
carcinoma
.
...
PMID:Methylenolactocin, a novel antitumor antibiotic from Penicillium sp. 340 69
