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Query: UMLS:C0007097 (carcinoma)
 152,788 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Between 1940 and 1967, we treated 609 patients with primary carcinoma of the esophagus by three different methods. In the first group of 170 patients, surgical resection predominated. In the next 166 patients, radiation therapy was used as the primary method. In a third group (135 patients) and a fourth group (138 patients), radiation therapy was followed by resection in the operable cases. After comparing the results of the three methods, we believe that radiation therapy followed by resection produces the best results. Moreover, this approach is justified by the discovery of residual carcinoma in most surgical specimens from patients who have had radiation therapy.
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PMID:Carcinoma of the esophagus. Long-term results. 5 1

234 patients, 146 with carcinoma of the oesophagus and 88 with carcinoma of the cardia are reported. There were 82 females and 152 males, mean age 62 years. The overall operability and resectability of the whole series was 38% and 23%. In cardiac carcinoma operability was 50% and resectability 32%, while in oesophageal carcinoma it was 31% and 18% respectively. 54 patients underwent resection, 44 received irradiation, and in 136 patients only palliative treatment was possible. The overall hospital mortality after resection was 15%, after oesophageal resection 12%, after cardiac resection 18%, and after palliative procedures 14%. Anastomotic leakage occurred in 9 patients (17%), four of whom died. The overall 5-year survival rate for the whole series was 4%, after resection 11%, and after radiotherapy 4%. No patient in the palliative group survived for 2 years. The mean survival time after irradiation was 11.5 months and after palliative procedures 5.5 months. The 5-year survival rate after oesophageal resection was 13% and after cardiac resection 6%.
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PMID:Carcinoma of the oesophagus and cardia. 6 91

The cytologic picture of small cell carcinoma primarily arising from the esophagus was studied with 7 cases which were confirmed by histologic examination. Cytomorphologic characteristics of small cell carcinoma of the esophagus are as follows: the arrangement of groups of tumor cells is irregular and overlapping with indistinct cell boundaries. The cytoplasm is small, or sometimes absent. The nuclei are round, oval or occasionally spindle shaped. Nuclear borders are thin. The chromatin of finely granular pattern has increased and is evenly distributed.
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PMID:A cytologic study on small cell carcinoma of the esophagus. 7 83

We retrospectively reviewed our experience with palliative dilation for dysphagia in esophageal carcinoma. During a 3-year period 26 patients with squamous-cell carcinoma of the esophagus underwent peroral esophageal dilation for relief of dysphagia. Twenty-four were able to resume a soft or regular diet after dilation. This improvement was accomplished with low morbidity and no mortality. Dilations were done without additional risk in patients with malignant tracheoesophageal fistulae and in patients undergoing radiation therapy. We conclude that esophageal dilation can be done safely and effectively in patients with squamous-cell carcinoma of the esophagus. Palliative dilation can significantly improve the quality of life for these patients and should be considered an important part of their management plan.
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PMID:Palliative dilation for dysphagia in esophageal carcinoma. 8 17

405 patient with carcinoma of the esophagus were operated on the unit from 1st January 1972 to 15th February 1977. Among these 405 patients, 55 underwent prolonged esophageal intubation and 24 a palliative operation. We considered successively the various methods of prolonged intubation and the various types of palliative operation possible. At the end of this study, it appears that palliative surgery for carcinoma of the esophagus owing to the severity of the operation and the high post-operative mortality and the doubtful functional results, should be reserved for eso-respiratory fistulas, per-operative loss of esophageal blood supply, and the contra-indications to prolonged intubation. On the other hand, it seems that the indications for prolonged intubation should be enlarged at the expense of those for gastrectomy, excluding however stenosing or too extensive carcinomas and carcinoma of the upper.
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PMID:[Palliative methods permitting oral feeding in patients with carcinoma of the esophagus (author's transl)]. 8 16

In 103 patients with a diagnosis of carcinoma of the esophagus, admission chest films were reviewed for abnormal findings attributable to the carcinoma. The presence or absence of these findings was analyzed and correlated with tumor resectability, complications, overall survival, and survival as related to tumor location. Unexpectedly, the group of patients who had normal films had a lower resectability rate (30% vs. 41%). There was no significant difference in survival rates of patients with or without chest film abnormalities (12.4 vs. 11.7 months).
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PMID:Esophageal cancer: radiographic chest findings and their prognostic significance. 11 5

A primary oat-cell carcinoma of the oesophagus is described with an adjacent squamous carcinoma, both parts having characteristic ultrastructure. The origin of this mixed tumour is discussed together with the literature on oesophageal carcinomas having an oat-cell pattern.
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PMID:Oat-cell carcinoma of the oesophagus: a recently recognized entity. 18 68

A case of primary adenoid cystic carcinoma of the esophagus is reported. A 51-year-old male patient had a tumor in the lower third of the esophagus which was incidentally found during an examination for cholelithiasis, and resected successfully. The tumor exhibited a polypoid appearance covered by normal esophageal epithelium, localized entirely in the submucosal layer, and morphologically identical to adenoid cystic carcinoma in the salivary glands. The patient is still alive and well three and one-half years after surgery. This seems to be a typical case of adenoid cystic carcinoma of the esophagus arising from the submucosal esophageal gland.
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PMID:Primary adenoid cystic carcinoma of the esophagus: report of a case. 22 27

Cytology and biopsy under direct vision using a fiberscope as microscopic diagnostic procedures for carcinoma of the esophagus and stomach were described, and results of cytology were evaluated as compared with the results of biopsy. The diagnostic accuracy of brushing cytology under direct vision using a fiberscope was 97% in 116 cases of esophageal carcinoma and 78% both in 119 patients with carcinoma of the gastric cardia and in 63 patients with gastric carcinoma exclusive of the cardia. The diagnostic accuracy for cytology of pancreatic juice collected by cannulation in 36 patients with carcinoma of the pancreas was 56%: 79% for carcinoma of the head of the pancreas, but only 35% for carcinoma of the body and/or tail. For the esophagus and stomach, the diagnostic accuracy of direct vision biopsy has become almost as high as with cytology. As such biopsies are easily performed, esophagogastric cytology has become in our clinics a supplementary routine to the biopsy, and is done in a limited number of cases in which the biopsy failed or was not appropriate. However, cytology of the pancreas, in which biopsy is difficult, is important as the only microscopic diagnostic procedure. There, the development of newer instruments and the improvement of techniques of cell collecting are required, as is the development of expertise in the interpretation of cells from pancreatic carcinoma, in which the diagnostic accuracy is still relatively low.
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PMID:Endoscopic cytology of the esophagus, stomach and pancreas. 28 39

Nine cases of severe gastrointestinal haemorrhage as the presentation of oesophageal lesions are reported. Haemorrhages complicating oesophageal varices, carcinoma of the oesophagus and oesophageal surgery were eliminated from the study, as were haemorrhages associated with hiatal hernias or Mallory-Weiss syndrome. Amongst these 9 cases of severe haemorrhage, 5 were due to an ulcer of the oesophagus, 2 to acute oesophagitis, 1 to rupture of the oesophagus and one to a traumatic aneurysm of the aorta rupturing into the oesophagus. The location and cause of bleeding were determined only 3 times before operation and only when a fibroscopic examination had been carried out. At fibroscopy, an irregular lesion responsible for a severe haemorrhage has every chance of being a benign ulcer and not a carcinoma. Treatment directed at the aetiology was carried out in 6 cases and success obtained in 3 patients. The aetiological diagnosis who was not made in 3 patients, who died. The aetiology, diagnosis and therapeutic approach required in such cases of severe haemorrhage of oesophageal origin are considered. In the light of these cases, a possible oesophageal aetiology should be considered as a possible cause of an unexplained severe gastrointestinal haemorrhage. An attempt at proving such a hypothesis by fibroscopy is necessary and, in general, urgent thoracotomy since the bleeding is in most instances of arterial origin.
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PMID:[Major esophageal hemorrhages of unusual origin. A poorly known entity]. 30 Apr 77


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