Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0007095 (carcinoid)
 6,990 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Carcinoid tumors are rich in somatostatin receptors and show high uptake of radiotracer on octreotide scintigraphy. 68Ga-DOTATATE could be of great help at initial staging and during follow-up of these patients. We describe a patient with avid 68Ga-DOTATATE and poor F18-FDG uptake.
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PMID:Is 68Ga-DOTATATE the answer in lung carcinoid? : Case report and review of literature. 2324 56

Some malignant lung neoplasms may demonstrate low or absent uptake on F18-fluorodeoxyglucose (FDG) PET/computed tomography. Pathologic type and clinical stage are independent factors associated with FDG avidity. Among lung malignancies with low FDG avidity, adenocarcinoma in situ and carcinoid are the most common. Early stage disease often has low FDG uptake. Small lesion size is another significant factor associated with negative FDG PET findings, which is due to a partial volume effect. Morphology of lung lesions on anatomic images may also affect FDG avidity. Subsolid pulmonary nodules, ground-glass nodules, or ground-glass opacity may be sources of false-negative PET.
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PMID:Lung Neoplasms with Low F18-Fluorodeoxyglucose Avidity. 2915 81