Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0006826 (cancer)
 1,092,456 document(s) hit in 31,850,051 MEDLINE articles (0.41 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 68828
Mol 46002
p53 30066
cytokine 12920
caspase-3 9401
lymphoid 8866
epidermal growth factor receptor 8819
Bcl-2 8564
tyrosine kinase 8108
AKT 8026
mTOR 7700
CD8 7658
PI3K 7070
histone 7022
vascular endothelial growth factor 6908
p21 6573
estrogen receptor 6520
ATP 6339
cage 6168
EGFR 5968
insulin 5865
CD4 5723
HER2 5673
catenin 5391
interferon 5322
MAPK 5287
E-cadherin 5273
ERK 5186
NMR 5111
collagen 5026
nodal 4945
tumor necrosis factor 4943
osteosarcoma 4818
MRI 4710
BRCA1 4628
IFN 4391
cyclin D1 4386
TNF 4332
proteasome 4261
PARP 4018
IL-6 3991
VEGF 3940
P-glycoprotein 3936
BRAF 3895
endoplasmic reticulum 3871
glycoprotein 3816
non-Hodgkin's lymphoma 3782
ACS 3746
TNM 3734
CD44 3734
PTEN 3707
ubiquitin 3687
STAT3 3490
matrix metalloproteinase 3393
KRAS 3391
HLA 3387
She 3358
p38 3345
carcinoembryonic antigen 3307
colon carcinoma 3303
PD-1 3248
ERK1 3183
PD-L1 3131
gut 3091
histone deacetylase 3084
Ki-67 3076
epidermal growth factor 3039
vimentin 3031
MEK 2946
ROS 2945
ras 2912
p16 2906
androgen receptor 2904
GSH 2849
PC-3 2839
prostate-specific antigen 2824
BRCA2 2817
IL-2 2813
fused 2793
cytochrome c 2679
more...
Disease
cancer 1092456
tumor 272229
breast cancer 73177
carcinoma 54437
metastases 42306
tumor growth 32490
lung cancer 31891
carcinogenesis 30464
tumorigenesis 29871
adenocarcinoma 28789
colorectal cancer 28170
prostate cancer 28040
melanoma 27569
tumor progression 24351
leukemia 24147
hepatocellular carcinoma 21368
squamous cell carcinoma 18670
lymphoma 17669
gastric cancer 16740
ovarian cancer 16260
colon cancer 15677
MCF 12972
diabetes 12555
pancreatic cancer 11877
cervical cancer 11225
non-small cell lung cancer 10559
acute myeloid leukemia 9744
glioma 9507
Hodgkin's disease 9100
primary tumor 9003
multiple myeloma 8996
renal cell carcinoma 8318
sarcoma 8086
obesity 7966
bladder cancer 7896
glioblastoma 7536
lung carcinoma 7291
liver cancer 6595
acute lymphoblastic leukemia 6211
cardiovascular disease 5998
epithelial ovarian cancer 5898
neuroblastoma 5814
osteosarcoma 5588
HIV 5574
infectious diseases 5449
liver cancer 5403
endometrial cancer 5384
dysplasia 5349
anemia 5204
skin cancer 5064
depression 5009
adenoma 4942
hypertension 4719
aggressiveness 4699
non-Hodgkin's lymphoma 4679
chronic myeloid leukemia 4503
Epstein 4484
esophageal cancer 4388
AIDS 4384
B-cell lymphoma 4119
chronic lymphocytic leukemia 4116
neutropenia 4082
Hepatocellular carcinoma 4067
thyroid cancer 4044
cirrhosis 3969
esophageal cancer 3918
head and neck cancer 3891
solid tumor 3844
immunodeficiency 3589
brain tumor 3520
retinoblastoma 3457
hematologic malignancies 3421
thrombocytopenia 3371
tumor angiogenesis 3347
myelodysplastic syndrome 3326
metastatic breast cancer 3299
chronic lymphocytic leukemia 3229
glioblastoma multiforme 3119
rectal cancer 3083
stroke 3047
more...
Symptom
pain 13058
fatigue 4247
nausea 3271
vomiting 3199
diarrhea 3134
cachexia 2503
abdominal pain 2272
nausea and vomiting 2232
anorexia 1929
dyspnea 1828
anesthesia 1676
cancer pain 1631
starvation 1474
weakness 1390
headache 1381
overweight 1283
discomfort 1248
cough 1049
discomfort 984
exhaustion 962
constipation 930
analgesia 913
seizures 898
collapse 862
splenomegaly 842
bone pain 824
erythema 668
chest pain 597
back pain 564
hemoptysis 543
Ill 462
insomnia 449
ataxia 440
acidity 420
respiratory distress 411
sleepiness 391
hepatomegaly 362
chills 360
hepatosplenomegaly 350
shortness of breath 344
asthenia 340
epigastric pain 310
ENT 307
stigma 305
arthralgia 290
dizziness 284
hoarseness 280
myalgia 270
menopausal symptoms 255
numbness 253
lethargy 243
fever of unknown origin 233
paresthesia 225
HSA 223
flushing 222
pelvic pain 215
low back pain 197
flank pain 196
breakthrough pain 194
nipple discharge 190
colic 190
agitation 185
acute pain 184
dysuria 181
angina 179
nipple discharge 174
hopelessness 173
hot flashes 160
abdominal discomfort 160
decreased appetite 158
cerebellar ataxia 156
night sweats 150
hypothermia 147
paresis 146
acute abdomen 140
syncope 132
tremor 132
hot flushes 128
thinning 125
myoclonus 123
more...
Drug
Dermatol 4195
lysine 3513
ROS 2944
IL-2 2891
CSF 2183
IFN-gamma 2167
Adriamycin 2100
ascorbate 1656
vitamin E 1550
Cardiovasc 1489
Taxol 1153
CTX 988
Herceptin 982
Monit 957
MAP 882
ROC 872
ADR 801
CPT-11 754
Imatinib 734
ABC 721
G-CSF 716
Mutagen 707
caffeine 667
Docetaxel 666
NADH 611
Sorafenib 604
Bevacizumab 577
GEO 557
Gefitinib 533
EPA 522
Bortezomib 504
ADM 488
Glutathione 478
ENT 476
ETS 469
uPA 462
Rituximab 459
MRC 453
Gleevec 452
Cetuximab 445
Gel 427
BLM 426
Paraffin 411
Leaf 409
Etoposide 382
ICI 382
CAM 381
Oxaliplatin 375
MDS 367
Irinotecan 349
Meth 344
VCR 342
Retinoic acid 329
CTX 328
PTC 328
Spectrum 311
EE2 309
Vitamin E 307
CTX 299
NVP 282
Asn 279
TAT 279
ALA 277
Erlotinib 277
THF 271
Arsenic trioxide 263
Vitamin A 259
Estrogens 258
IFN-beta 251
ZnO 246
Indomethacin 241
lactose 239
HCG 233
PTH 230
CTC 229
TEL 221
Albumin 221
Portal 219
Photofrin 218
-deoxyadenosine 218
more...
Enzyme
ERK 25120
mitogen-activated protein kinase 14230
focal adhesion kinase 7623
caspase-3 7334
protein kinase 6994
luciferase 5867
PARP 4520
proteasome 4327
P-glycoprotein 3963
MEK 3808
ACS 3759
protein kinase C 2760
prostate-specific antigen 2641
topoisomerase 2558
topoisomerase 2377
reverse transcriptase 2375
glutathione S-transferase 2291
APC 2198
catalase 2099
caspase-9 2062
ATPase 2004
superoxide dismutase 1981
peroxidase 1974
urokinase-type plasminogen activator 1865
AMP-activated protein kinase 1860
alkaline phosphatase 1826
lactate dehydrogenase 1819
caspase-8 1812
phosphatidylinositol 3-kinase 1723
cdc2 1713
RNA polymerase 1462
phosphoinositide 3-kinase 1334
thymidine kinase 1268
AMPK 1250
trypsin 1195
DNA methyltransferase 1162
collagenase 1141
AMPK 1080
calcineurin 1050
ornithine decarboxylase 1043
glutathione peroxidase 1038
thymidylate synthase 1038
DNA polymerase 1037
GSK 1004
alanine aminotransferase 977
MMP 913
NQO1 905
thrombin 879
RNase 851
gamma-glutamyl transpeptidase 838
RNase 782
aspartate aminotransferase 771
MDR 763
aldehyde dehydrogenase 752
endonuclease 734
IKK 726
aldehyde dehydrogenase 716
CD10 708
aldehyde dehydrogenase 681
aldehyde dehydrogenase 681
aldehyde dehydrogenase 681
granzyme B 636
demethylase 612
dihydrofolate reductase 588
neuraminidase 568
tyrosinase 566
beta-galactosidase 560
cathepsin B 548
plasmin 539
matrix metalloproteinase 2 525
MAP 517
asparaginase 505
ribonucleotide reductase 499
phosphodiesterase 498
prostate-specific membrane antigen 490
PDK1 490
acid phosphatase 487
transcriptase 485
ribonucleotide reductase 477
succinate dehydrogenase 446
more...
Compound
DNA 89644
Dec 73291
Clin 70800
oxygen 20348
BMC 12140
water 12054
Pac 11459
MDA 9419
glucose 8984
MTT 8509
calcium 7626
tyrosine 7551
ATP 6347
sodium 5594
acetate 5403
iron 5299
phosphate 5017
PEG 4743
lysine 4341
TNF 4332
serine 4222
hydrogen 4001
methionine 3980
cysteine 3958
ACS 3760
ACS 3746
TNM 3734
Adriamycin 3679
arginine 3602
sulfate 3453
iodine 3451
PEG 3399
zinc 3254
nitrogen 3200
GSH 3163
GSH 3162
retinoic acid 3118
ethanol 3008
DDP 2958
MEK 2903
nitric oxide 2876
threonine 2772
5-FU 2725
bromide 2707
ADR 2532
galactose 2507
copper 2454
pyrene 2328
vitamin D 2309
selenium 2242
His 2228
anthracene 2218
leucine 2165
creatinine 2149
urea 1934
DBA 1792
alanine 1743
pyrimidine 1741
pyrimidine 1729
glutamine 1709
salt 1688
Curcumin 1543
boron 1480
NAD 1478
silver 1470
ADP 1401
Asp 1363
Phe 1348
Thyroid 1325
AMP 1314
tryptophan 1304
NH2 1295
methanol 1284
potassium 1275
cAMP 1255
ADP 1236
ADP 1233
NAD 1209
Paclitaxel 1145
hyaluronic acid 1138
more...