Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0006826 (cancer)
1,092,456 document(s) hit in 31,850,051 MEDLINE articles (0.42 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 68828
Mol 46002
p53 30066
cytokine 12920
caspase-3 9401
lymphoid 8866
epidermal growth factor receptor 8819
Bcl-2 8564
tyrosine kinase 8108
AKT 8026
mTOR 7700
CD8 7658
PI3K 7070
histone 7022
vascular endothelial growth factor 6908
p21 6573
estrogen receptor 6520
ATP 6339
cage 6168
EGFR 5968
insulin 5865
CD4 5723
HER2 5673
catenin 5391
interferon 5322
MAPK 5287
E-cadherin 5273
ERK 5186
NMR 5111
collagen 5026
nodal 4945
tumor necrosis factor 4943
osteosarcoma 4818
MRI 4710
BRCA1 4628
IFN 4391
cyclin D1 4386
TNF 4332
proteasome 4261
PARP 4018
more...
Disease
cancer 1092456
tumor 272229
breast cancer 73177
carcinoma 54437
metastases 42306
tumor growth 32490
lung cancer 31891
carcinogenesis 30464
tumorigenesis 29871
adenocarcinoma 28789
colorectal cancer 28170
prostate cancer 28040
melanoma 27569
tumor progression 24351
leukemia 24147
hepatocellular carcinoma 21368
squamous cell carcinoma 18670
lymphoma 17669
gastric cancer 16740
ovarian cancer 16260
colon cancer 15677
MCF 12972
diabetes 12555
pancreatic cancer 11877
cervical cancer 11225
non-small cell lung cancer 10559
acute myeloid leukemia 9744
glioma 9507
Hodgkin's disease 9100
primary tumor 9003
multiple myeloma 8996
renal cell carcinoma 8318
sarcoma 8086
obesity 7966
bladder cancer 7896
glioblastoma 7536
lung carcinoma 7291
liver cancer 6595
acute lymphoblastic leukemia 6211
cardiovascular disease 5998
more...
Symptom
pain 13058
fatigue 4247
nausea 3271
vomiting 3199
diarrhea 3134
cachexia 2503
abdominal pain 2272
nausea and vomiting 2232
anorexia 1929
dyspnea 1828
anesthesia 1676
cancer pain 1631
starvation 1474
weakness 1390
headache 1381
overweight 1283
discomfort 1248
cough 1049
discomfort 984
exhaustion 962
constipation 930
analgesia 913
seizures 898
collapse 862
splenomegaly 842
bone pain 824
erythema 668
chest pain 597
back pain 564
hemoptysis 543
Ill 462
insomnia 449
ataxia 440
acidity 420
respiratory distress 411
sleepiness 391
hepatomegaly 362
chills 360
hepatosplenomegaly 350
shortness of breath 344
more...
Drug
Dermatol 4195
lysine 3513
ROS 2944
IL-2 2891
CSF 2183
IFN-gamma 2167
Adriamycin 2100
ascorbate 1656
vitamin E 1550
Cardiovasc 1489
Taxol 1153
CTX 988
Herceptin 982
Monit 957
MAP 882
ROC 872
ADR 801
CPT-11 754
Imatinib 734
ABC 721
G-CSF 716
Mutagen 707
caffeine 667
Docetaxel 666
NADH 611
Sorafenib 604
Bevacizumab 577
GEO 557
Gefitinib 533
EPA 522
Bortezomib 504
ADM 488
Glutathione 478
ENT 476
ETS 469
uPA 462
Rituximab 459
MRC 453
Gleevec 452
Cetuximab 445
more...
Enzyme
ERK 25120
mitogen-activated protein kinase 14230
focal adhesion kinase 7623
caspase-3 7334
protein kinase 6994
luciferase 5867
PARP 4520
proteasome 4327
P-glycoprotein 3963
MEK 3808
ACS 3759
protein kinase C 2760
prostate-specific antigen 2641
topoisomerase 2558
topoisomerase 2377
reverse transcriptase 2375
glutathione S-transferase 2291
APC 2198
catalase 2099
caspase-9 2062
ATPase 2004
superoxide dismutase 1981
peroxidase 1974
urokinase-type plasminogen activator 1865
AMP-activated protein kinase 1860
alkaline phosphatase 1826
lactate dehydrogenase 1819
caspase-8 1812
phosphatidylinositol 3-kinase 1723
cdc2 1713
RNA polymerase 1462
phosphoinositide 3-kinase 1334
thymidine kinase 1268
AMPK 1250
trypsin 1195
DNA methyltransferase 1162
collagenase 1141
AMPK 1080
calcineurin 1050
ornithine decarboxylase 1043
more...
Compound
DNA 89644
Dec 73291
Clin 70800
oxygen 20348
BMC 12140
water 12054
Pac 11459
MDA 9419
glucose 8984
MTT 8509
calcium 7626
tyrosine 7551
ATP 6347
sodium 5594
acetate 5403
iron 5299
phosphate 5017
PEG 4743
lysine 4341
TNF 4332
serine 4222
hydrogen 4001
methionine 3980
cysteine 3958
ACS 3760
ACS 3746
TNM 3734
Adriamycin 3679
arginine 3602
sulfate 3453
iodine 3451
PEG 3399
zinc 3254
nitrogen 3200
GSH 3163
GSH 3162
retinoic acid 3118
ethanol 3008
DDP 2958
MEK 2903
more...