Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0006826 (cancer)
1,092,456 document(s) hit in 31,850,051 MEDLINE articles (0.59 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 68828 Mol 46002 p53 30066 cytokine 12920 caspase-3 9401 lymphoid 8866 epidermal growth factor receptor 8819 Bcl-2 8564 tyrosine kinase 8108 AKT 8026 mTOR 7700 CD8 7658 PI3K 7070 histone 7022 vascular endothelial growth factor 6908 p21 6573 estrogen receptor 6520 ATP 6339 cage 6168 EGFR 5968 insulin 5865 CD4 5723 HER2 5673 catenin 5391 interferon 5322 MAPK 5287 E-cadherin 5273 ERK 5186 NMR 5111 collagen 5026 nodal 4945 tumor necrosis factor 4943 osteosarcoma 4818 MRI 4710 BRCA1 4628 IFN 4391 cyclin D1 4386 TNF 4332 proteasome 4261 PARP 4018 IL-6 3991 VEGF 3940 P-glycoprotein 3936 BRAF 3895 endoplasmic reticulum 3871 glycoprotein 3816 non-Hodgkin's lymphoma 3782 ACS 3746 CD44 3734 TNM 3734 PTEN 3707 ubiquitin 3687 STAT3 3490 matrix metalloproteinase 3393 KRAS 3391 HLA 3387 She 3358 p38 3345 carcinoembryonic antigen 3307 colon carcinoma 3303 PD-1 3248 ERK1 3183 PD-L1 3131 gut 3091 histone deacetylase 3084 Ki-67 3076 epidermal growth factor 3039 vimentin 3031 MEK 2946 ROS 2945 ras 2912 p16 2906 androgen receptor 2904 GSH 2849 PC-3 2839 prostate-specific antigen 2824 BRCA2 2817 IL-2 2813 fused 2793 cytochrome c 2679 interleukin-2 2659 progesterone receptor 2654 tumour suppressor 2634 chemokine 2622 PEG 2583 receptor tyrosine kinase 2564 caspase-9 2553 c-Myc 2549 fibronectin 2541 albumin 2541 MMP-9 2540 c-myc 2496 JNK 2424 survivin 2420 annexin V 2388 FDG 2385 p27 2376 hemoglobin 2370 thymus 2345 telomeric 2333 caspase-8 2331 mucin 2321 MYC 2308 proliferating cell nuclear antigen 2240 cyclin 2233 IFN-gamma 2227 phosphatase 2206 MMP-2 2202 UTR 2196 rhabdomyosarcoma 2193 PC3 2120 cyclooxygenase-2 2118 polypeptide 2108 serum albumin 2101 EGF 2075 Fas 2066 COX-2 2048 beta-catenin 2031 proto-oncogene 2018 IL-10 2009 Pol 1977 MHC 1957 extracellular signal-regulated kinase 1955 CD133 1951 ATM 1935 CD34 1934 APC 1922 erbB-2 1894 IL-8 1887 lectin 1869 threonine 1847 alkaline phosphatase 1817 CEA 1815 interleukin-6 1799 insulin-like growth factor 1797 ATPase 1767 p65 1766 lipopolysaccharide 1765 granulocyte 1757 catalase 1751 phosphatidylinositol 3-kinase 1723 MDM2 1703 mutant p53 1685 MET 1669 c-Jun 1643 superoxide dismutase 1626 lactate dehydrogenase 1624 bcl-2 1618 CDK4 1610 Rho 1596 urokinase-type plasminogen activator 1596 hormone receptor 1587 CXCR4 1575 PIK3CA 1566 VEGFR2 1561 neu 1552 aromatase 1546 alpha-fetoprotein 1542 PSA 1530 histone H3 1528 more...

Disease cancer 1092456 tumor 272229 breast cancer 73177 carcinoma 54437 metastases 42306 tumor growth 32490 lung cancer 31891 carcinogenesis 30464 tumorigenesis 29871 adenocarcinoma 28789 colorectal cancer 28170 prostate cancer 28040 melanoma 27569 tumor progression 24351 leukemia 24147 hepatocellular carcinoma 21368 squamous cell carcinoma 18670 lymphoma 17669 gastric cancer 16740 ovarian cancer 16260 colon cancer 15677 MCF 12972 diabetes 12555 pancreatic cancer 11877 cervical cancer 11225 non-small cell lung cancer 10559 acute myeloid leukemia 9744 glioma 9507 Hodgkin's disease 9100 primary tumor 9003 multiple myeloma 8996 renal cell carcinoma 8318 sarcoma 8086 obesity 7966 bladder cancer 7896 glioblastoma 7536 lung carcinoma 7291 liver cancer 6595 acute lymphoblastic leukemia 6211 cardiovascular disease 5998 epithelial ovarian cancer 5898 neuroblastoma 5814 osteosarcoma 5588 HIV 5574 infectious diseases 5449 liver cancer 5403 endometrial cancer 5384 dysplasia 5349 anemia 5204 skin cancer 5064 depression 5009 adenoma 4942 hypertension 4719 aggressiveness 4699 non-Hodgkin's lymphoma 4679 chronic myeloid leukemia 4503 Epstein 4484 esophageal cancer 4388 AIDS 4384 B-cell lymphoma 4119 chronic lymphocytic leukemia 4116 neutropenia 4082 Hepatocellular carcinoma 4067 thyroid cancer 4044 cirrhosis 3969 esophageal cancer 3918 head and neck cancer 3891 solid tumor 3844 immunodeficiency 3589 brain tumor 3520 retinoblastoma 3457 hematologic malignancies 3421 thrombocytopenia 3371 tumor angiogenesis 3347 myelodysplastic syndrome 3326 metastatic breast cancer 3299 chronic lymphocytic leukemia 3229 glioblastoma multiforme 3119 rectal cancer 3083 stroke 3047 oral cancer 3046 hepatitis B 2937 childhood cancer 2934 ATM 2888 GSH 2851 atherosclerosis 2848 liver metastases 2840 Alzheimer's disease 2838 small cell lung cancer 2838 sepsis 2771 tuberculosis 2692 renal cancer 2689 mesothelioma 2662 fibrosarcoma 2652 pneumonia 2618 virus infection 2605 metastatic melanoma 2595 uterus 2558 bone metastases 2546 residual disease 2529 sepsis 2488 rheumatoid arthritis 2486 mammary tumor 2475 tumor initiation 2400 Leukemia 2382 Melanoma 2370 heart disease 2357 osteoporosis 2356 WT1 2344 acute leukemia 2302 myelosuppression 2283 type 2 diabetes 2261 lymphadenopathy 2236 cold 2212 lung metastases 2205 graft-versus-host disease 2154 SCID 2122 Kaposi's sarcoma 2114 Burkitt's lymphoma 2080 rhabdomyosarcoma 2079 APC 2036 inflammatory bowel disease 2035 hypercalcemia 2022 neoplastic transformation 2021 liver disease 2000 heart failure 1999 carcinoma in situ 1982 basal cell carcinoma 1864 acute promyelocytic leukemia 1856 invasive cancer 1842 herpes simplex 1840 asthma 1833 uterine cervix 1824 arthritis 1814 malnutrition 1737 colitis 1723 Ewing's sarcoma 1689 aggression 1688 hepatitis C 1681 autoimmune disease 1676 brain metastases 1669 Infection 1662 suicide 1644 testicular cancer 1642 familial adenomatous polyposis 1609 medulloblastoma 1606 hepatitis 1595 Barrett's esophagus 1568 ulcerative colitis 1553 PSA 1531 West 1515 polyposis 1508 ductal carcinoma in situ 1498 infertility 1486 renal disease 1483 papilloma 1457 ischemia 1446 cervical intraepithelial neoplasia 1444 leukopenia 1437 cytomegalovirus 1428 more...

Symptom pain 13058 fatigue 4247 nausea 3271 vomiting 3199 diarrhea 3134 cachexia 2503 abdominal pain 2272 nausea and vomiting 2232 anorexia 1929 dyspnea 1828 anesthesia 1676 cancer pain 1631 starvation 1474 weakness 1390 headache 1381 overweight 1283 discomfort 1248 cough 1049 discomfort 984 exhaustion 962 constipation 930 analgesia 913 seizures 898 collapse 862 splenomegaly 842 bone pain 824 erythema 668 chest pain 597 back pain 564 hemoptysis 543 Ill 462 insomnia 449 ataxia 440 acidity 420 respiratory distress 411 sleepiness 391 hepatomegaly 362 chills 360 hepatosplenomegaly 350 shortness of breath 344 asthenia 340 epigastric pain 310 ENT 307 stigma 305 arthralgia 290 dizziness 284 hoarseness 280 myalgia 270 menopausal symptoms 255 numbness 253 lethargy 243 fever of unknown origin 233 paresthesia 225 HSA 223 flushing 222 pelvic pain 215 low back pain 197 flank pain 196 breakthrough pain 194 nipple discharge 190 colic 190 agitation 185 acute pain 184 dysuria 181 angina 179 nipple discharge 174 hopelessness 173 hot flashes 160 abdominal discomfort 160 decreased appetite 158 cerebellar ataxia 156 night sweats 150 hypothermia 147 paresis 146 acute abdomen 140 syncope 132 tremor 132 hot flushes 128 thinning 125 myoclonus 123 functional recovery 123 skin damage 111 distraction 107 masculinization 105 exertional dyspnea 101 Neuropathic pain 100 acute abdominal pain 99 regurgitation 97 sore throat 94 tinnitus 92 dysarthria 89 neck pain 89 bloating 87 vertigo 84 heartburn 83 memory loss 83 rigors 82 pallor 81 hyperoxia 80 acute stress 78 chronic cough 78 stridor 75 blurred vision 74 spasm 69 spasticity 68 facial pain 68 clubbing 67 hypoproteinemia 66 shoulder pain 65 Wind 65 tenesmus 65 abdominal fullness 64 hunger 63 polyuria 63 despair 63 wheezing 61 Scratch 61 mastalgia 61 tachypnea 61 productive cough 58 physical appearance 58 otalgia 57 oliguria 57 apathy 56 paraparesis 56 tingling 54 ophthalmoplegia 54 urinary frequency 53 neuralgia 53 hip pain 52 leg pain 51 intestinal bleeding 50 skin irritation 50 hemiplegia 49 right upper quadrant pain 49 physical symptom 48 cyanosis 48 polydipsia 47 Depressive symptoms 46 dystonia 45 rhinorrhea 45 dry eye 44 Sister Mary Joseph's nodule 44 dry skin 44 retching 43 Sedation 41 hypotonia 41 knee pain 41 pleuritic chest pain 39 leg edema 39 chronic constipation 38 anosmia 38 tense 36 dysesthesia 36 hypercapnia 35 incoordination 34 anal pain 34 persistent cough 34 bitter taste 34 consciousness disturbance 33 more...

Drug Dermatol 4195 lysine 3513 ROS 2944 IL-2 2891 CSF 2183 IFN-gamma 2167 Adriamycin 2100 ascorbate 1656 vitamin E 1550 Cardiovasc 1489 Taxol 1153 CTX 988 Herceptin 982 Monit 957 MAP 882 ROC 872 ADR 801 CPT-11 754 Imatinib 734 ABC 721 G-CSF 716 Mutagen 707 caffeine 667 Docetaxel 666 NADH 611 Sorafenib 604 Bevacizumab 577 GEO 557 Gefitinib 533 EPA 522 Bortezomib 504 ADM 488 Glutathione 478 ENT 476 ETS 469 uPA 462 Rituximab 459 MRC 453 Gleevec 452 Cetuximab 445 Gel 427 BLM 426 Paraffin 411 Leaf 409 Etoposide 382 ICI 382 CAM 381 Oxaliplatin 375 MDS 367 Irinotecan 349 Meth 344 VCR 342 Retinoic acid 329 CTX 328 PTC 328 Spectrum 311 EE2 309 Vitamin E 307 CTX 299 NVP 282 TAT 279 Asn 279 ALA 277 Erlotinib 277 THF 271 Arsenic trioxide 263 Vitamin A 259 Estrogens 258 IFN-beta 251 ZnO 246 Indomethacin 241 lactose 239 HCG 233 PTH 230 CTC 229 TEL 221 Albumin 221 Portal 219 Photofrin 218 -deoxyadenosine 218 DM1 218 TTC 217 CTC 216 p75 214 Zoledronic acid 211 Taxotere 210 G418 205 DNase I 204 citric acid 196 Alliance 195 VCR 177 Tocopherol 172 Fluorescein 172 Ipilimumab 170 Vorinostat 169 Lenalidomide 167 Dial 166 Bifidobacterium 165 Leucovorin 164 Zoledronic acid 164 Ethanol 162 Lipiodol 160 Everolimus 160 niacin 157 Cremophor EL 151 Nephron 147 Dasatinib 146 Heme 144 Pemetrexed 143 CCL 141 Gelatin 141 Vinorelbine 138 Fraction 138 Asthma 133 ampicillin 133 Biopolymers 132 Amifostine 126 NH3 126 Ginseng 121 TiO2 120 nitroglycerin 119 Activin 119 AZT 119 Raloxifene 119 IL-11 116 FAD 116 Norplant 113 Glycyrrhiza 113 Denosumab 112 MTC 112 Itraconazole 111 Lovastatin 111 Simvastatin 111 Fulvestrant 109 Fludarabine 108 Emodin 108 Parkin 108 Parkin 108 AZT 108 ACT 106 PCB 106 Nephron 105 Emodin 105 R1881 103 TAC 103 RFP 102 Growth hormone 101 Growth hormone 101 anti-CD33 100 Tarceva 100 Kenyan 99 Campath 98 Campath 98 Photofrin II 96 Fluorescein 96 Epigallocatechin 95 Fragment 94 Spectrum 94 Angiotensin II 94 TAK 94 more...

Enzyme ERK 25120 mitogen-activated protein kinase 14230 focal adhesion kinase 7623 caspase-3 7334 protein kinase 6994 luciferase 5867 PARP 4520 proteasome 4327 P-glycoprotein 3963 MEK 3808 ACS 3759 protein kinase C 2760 prostate-specific antigen 2641 topoisomerase 2558 topoisomerase 2377 reverse transcriptase 2375 glutathione S-transferase 2291 APC 2198 catalase 2099 caspase-9 2062 ATPase 2004 superoxide dismutase 1981 peroxidase 1974 urokinase-type plasminogen activator 1865 AMP-activated protein kinase 1860 alkaline phosphatase 1826 lactate dehydrogenase 1819 caspase-8 1812 phosphatidylinositol 3-kinase 1723 cdc2 1713 RNA polymerase 1462 phosphoinositide 3-kinase 1334 thymidine kinase 1268 AMPK 1250 trypsin 1195 DNA methyltransferase 1162 collagenase 1141 AMPK 1080 calcineurin 1050 ornithine decarboxylase 1043 glutathione peroxidase 1038 thymidylate synthase 1038 DNA polymerase 1037 GSK 1004 alanine aminotransferase 977 MMP 913 NQO1 905 thrombin 879 RNase 851 gamma-glutamyl transpeptidase 838 RNase 782 aspartate aminotransferase 771 MDR 763 aldehyde dehydrogenase 752 endonuclease 734 IKK 726 aldehyde dehydrogenase 716 CD10 708 aldehyde dehydrogenase 681 aldehyde dehydrogenase 681 aldehyde dehydrogenase 681 granzyme B 636 demethylase 612 dihydrofolate reductase 588 neuraminidase 568 tyrosinase 566 beta-galactosidase 560 cathepsin B 548 plasmin 539 matrix metalloproteinase 2 525 MAP 517 asparaginase 505 ribonucleotide reductase 499 phosphodiesterase 498 prostate-specific membrane antigen 490 PDK1 490 acid phosphatase 487 transcriptase 485 ribonucleotide reductase 477 succinate dehydrogenase 446 cathepsin D 432 ricin 429 CYP3A4 423 phospholipase C 416 glutathione reductase 412 creatine kinase 405 NADPH oxidase 401 matrix metalloproteinase 9 400 pyruvate kinase 398 complex I 395 lipoxygenase 388 caspase-1 383 lysozyme 380 dihydropyrimidine dehydrogenase 375 NADPH oxidase 373 thromboplastin 369 thioredoxin reductase 362 polo-like kinase 1 358 hyaluronidase 357 glyceraldehyde-3-phosphate dehydrogenase 356 ALDH 354 hexokinase 343 isocitrate dehydrogenase 343 adenosine deaminase 342 tissue plasminogen activator 342 protein phosphatase 2A 341 adenosine deaminase 340 renin 340 isocitrate dehydrogenase 339 ACE 339 MMP-3 338 phospholipase A2 337 CD13 337 hyaluronidase 330 cytosine deaminase 330 carbonic anhydrase 321 arginase 319 thymidine phosphorylase 318 beta-glucuronidase 316 glucose-6-phosphate dehydrogenase 312 dihydropyrimidine dehydrogenase 311 glutaminase 309 histone acetyltransferase 300 NO synthase 300 NOS 292 acetylcholinesterase 291 DNase 283 DNA ligase 282 enolase 282 TAT 282 DNA ligase 282 BMT 281 kinesin 279 adenylate cyclase 278 ribonuclease 274 ribonuclease 274 xanthine oxidase 273 STK11 263 kallikrein 263 alcohol dehydrogenase 262 lipase 262 hypoxanthine-guanine phosphoribosyltransferase 261 caspase-7 258 histone demethylase 257 caspase-7 256 pyruvate dehydrogenase 255 DCF 250 transglutaminase 249 farnesyltransferase 246 indoleamine 2,3-dioxygenase 238 farnesyltransferase 236 methylenetetrahydrofolate reductase 234 CPT 234 AST 234 methylenetetrahydrofolate reductase 234 firefly luciferase 232 aryl hydrocarbon hydroxylase 232 UDP-glucuronosyltransferase 217 glyceraldehyde-3-phosphate dehydrogenase 209 CPT 207 more...

Compound DNA 89644 Dec 73291 Clin 70800 oxygen 20348 BMC 12140 water 12054 Pac 11459 MDA 9419 glucose 8984 MTT 8509 calcium 7626 tyrosine 7551 ATP 6347 sodium 5594 acetate 5403 iron 5299 phosphate 5017 PEG 4743 lysine 4341 TNF 4332 serine 4222 hydrogen 4001 methionine 3980 cysteine 3958 ACS 3760 ACS 3746 TNM 3734 Adriamycin 3679 arginine 3602 sulfate 3453 iodine 3451 PEG 3399 zinc 3254 nitrogen 3200 GSH 3163 GSH 3162 retinoic acid 3118 ethanol 3008 DDP 2958 MEK 2903 nitric oxide 2876 threonine 2772 5-FU 2725 bromide 2707 ADR 2532 galactose 2507 copper 2454 pyrene 2328 vitamin D 2309 selenium 2242 His 2228 anthracene 2218 leucine 2165 creatinine 2149 urea 1934 DBA 1792 alanine 1743 pyrimidine 1741 pyrimidine 1729 glutamine 1709 salt 1688 Curcumin 1543 boron 1480 NAD 1478 silver 1470 ADP 1401 Asp 1363 Phe 1348 Thyroid 1325 AMP 1314 tryptophan 1304 NH2 1295 methanol 1284 potassium 1275 cAMP 1255 ADP 1236 ADP 1233 NAD 1209 Paclitaxel 1145 hyaluronic acid 1138 H2O2 1125 BCR 1125 TEM 1122 SCC 1119 formaldehyde 1116 glutamate 1097 ASA 1090 proline 1088 ABL 1086 tryptophan 1080 N-acetylcysteine 1077 VP-16 1064 Estrogen 1062 ADP-ribose 1058 GTP 1058 tryptophan 1045 tryptophan 1044 SDS 1034 CO2 1032 NADPH 1026 NADPH 1024 benzene 1009 Tamoxifen 999 pyridine 997 CTX 988 Histone 980 nicotinamide 976 Estrogen 976 Tamoxifen 973 barium 953 retinol 951 aldehyde 950 Resveratrol 935 Methotrexate 935 Optimal 925 Insulin 919 fluorine 901 Gly 894 TOF 874 DBA 861 DBA 852 acetic acid 837 ammonium 835 cadmium 828 Cardiol 814 acridine 812 BCG 799 BLM 773 BCNU 764 MDR 764 uridine 762 CPT-11 752 THP 746 dUTP 740 nickel 739 THP 730 PGA 724 DMSO 717 ethyl acetate 716 Vimentin 715 chromium 710 Metformin 709 Metformin 707 nitrate 700 Gemcitabine 693 Gemcitabine 692 aldehyde 686 formaldehyde 684 GlcNAc 673 cobalt 670 caffeine 669 quinoline 665 MAP 662 manganese 662 PGE2 656 phenol 656 PGE 651 quinoline 650 Vitamin D 644 PMA 642 more...

---