Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0006625 (cachexia)
5,650 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein cytokine 399 Sep 366 insulin 277 tumor necrosis factor 258 IL-6 226 ubiquitin 214 ghrelin 201 muscle protein 183 TNF 174 Mol 173 proteasome 170 leptin 148 interleukin-6 146 growth hormone 144 cage 140 myostatin 131 TNF-alpha 113 Ghrelin 93 gut 80 albumin 79 IL-1 78 Walker 70 atrogin-1 68 C-reactive protein 67 ATP 61 TNF-a 61 lipopolysaccharide 61 Tumor necrosis factor 56 She 55 mTOR 52 glycoprotein 52 tumor necrosis factor alpha 51 epididymal 49 neuropeptide Y 47 interferon 46 GHRP 46 ghrelin receptor 45 Cytokine 45 androgen receptor 45 serum albumin 40 IFN-gamma 40 lipoprotein lipase 40 IL-10 39 activin 39 Leptin 38 STAT3 37 insulin-like growth factor 37 Atrogin-1 36 MuRF1 36 LPS 35 collagen 34 MuRF 33 glucagon 33 MyoD 31 adiponectin 30 IL-8 30 myosin 30 angiotensin II 29 IGF-1 29 renin 29 interferon-gamma 29 cardiac muscle 29 interleukin 6 28 hemoglobin 28 beta-endorphin 28 myogenin 27 lymphoid 27 thymidine phosphorylase 27 IL-1 beta 26 myosin heavy chain 25 IGF-I 25 Pol 25 IFN 24 COPD 24 PGC 24 AKT 23 CD4 22 platelet-derived 22 p38 22 parathyroid hormone-related protein 22 more...

Disease cancer 2503 tumor 1153 muscular atrophy 648 wasting 526 malnutrition 373 obesity 297 heart failure 296 Cancer cachexia 257 tumor growth 257 adenocarcinoma 207 anemia 204 diabetes 179 AIDS 179 chronic obstructive pulmonary disease 147 sepsis 144 carcinoma 140 metastases 134 sepsis 133 depression 131 HIV 114 pancreatic cancer 111 lung cancer 111 wasting syndrome 100 hepatocellular carcinoma 86 rheumatoid arthritis 84 breast cancer 81 congestive heart failure 75 sarcoma 75 lung carcinoma 70 metabolic syndrome 69 immunodeficiency 69 anorexia nervosa 68 tumor progression 65 hypercalcemia 64 renal failure 63 chronic disease 60 arthritis 60 malabsorption 57 osteoporosis 57 colorectal cancer 56 melanoma 55 hypoglycemia 51 cardiovascular disease 51 leukemia 51 renal disease 51 pneumonia 50 tuberculosis 47 hypertension 47 dysphagia 45 infectious diseases 43 gastric cancer 42 tumorigenesis 41 type 2 diabetes 40 lymphoma 40 paraneoplastic syndrome 39 dehydration 38 squamous cell carcinoma 38 prostate cancer 36 peripheral neuropathy 36 multiple myeloma 36 hyperphagia 35 non-small cell lung cancer 33 renal cell carcinoma 33 bowel obstruction 33 Mycobacterium 31 gastrointestinal cancer 31 leukoencephalopathy 30 myopathy 29 prolapse 29 cirrhosis 29 thrombocytopenia 29 muscular dystrophy 28 hypogonadism 28 lymphadenopathy 28 respiratory failure 28 uremia 27 atherosclerosis 27 heart disease 26 dementia 26 liver disease 25 more...

Symptom cachexia 5650 anorexia 799 fatigue 201 pain 182 weakness 147 starvation 113 diarrhea 108 dyspnea 87 nausea 83 vomiting 74 asthenia 53 splenomegaly 40 abdominal pain 39 nausea and vomiting 36 constipation 35 lethargy 28 hepatosplenomegaly 23 Ill 22 anesthesia 20 overweight 20 hunger 20 emaciation 20 seizures 19 ataxia 18 decreased appetite 18 hepatomegaly 18 cough 16 exhaustion 15 ophthalmoplegia 15 cancer pain 15 regurgitation 13 spasticity 12 insomnia 12 hypothermia 12 discomfort 11 respiratory distress 11 headache 11 polyuria 10 discomfort 10 apathy 9 sleepiness 9 bone pain 9 tremor 9 back pain 8 erythema 8 polydipsia 8 pallor 8 hemoptysis 8 night sweats 7 abdominal discomfort 6 hypoproteinemia 6 paresis 6 tachypnea 6 inanition 6 flank pain 5 chills 5 dizziness 5 nasal discharge 5 numbness 4 bloating 4 incoordination 4 abdominal fullness 4 epigastric pain 4 chest pain 4 agitation 4 collapse 4 dysuria 4 dysarthria 4 exertional dyspnea 4 angina 4 arthralgia 4 colic 3 oliguria 3 acute stress 3 cyanosis 3 hypercapnia 3 aphagia 3 hypotonia 3 analgesia 2 distraction 2 more...

Drug IFN-gamma 39 Cardiovasc 24 IL-2 20 Activin 16 Dial 16 ROS 14 Indomethacin 13 Dermatol 12 Growth hormone 11 Growth hormone 10 MAP 10 GHRP 9 Spectrum 9 EPA 8 IL-11 8 vitamin E 7 Monit 7 lysine 7 Angiotensin II 6 CTX 6 CSF 6 Adriamycin 5 DMAP 5 AZT 4 NADH 4 CPT-11 4 9-THC 4 niacin 4 lactose 4 Serum albumin 4 citric acid 4 Albumin 4 AZT 4 Meth 3 Ginseng 3 Glycerol 3 IL-1ra 3 Paraffin 3 ACT 3 p75 3 Trental 3 Nephron 3 Asthma 3 Bifidobacterium 3 Parkin 3 CCL 3 Gastro 3 Parkin 3 Nitric Oxide 3 Rosiglitazone 3 Ponalrestat 2 PTH 2 Nabilone 2 Bezafibrate 2 Doxycycline 2 Docetaxel 2 Glutathione 2 CTX 2 CTX 2 EPI 2 Vitamin A 2 Mirtazapine 2 Aliskiren 2 G-CSF 2 Infliximab 2 Infliximab 2 Xanthium 2 Ketoconazole 2 ROC 2 ascorbate 2 Ofloxacin 1 Asn 1 Thalomid 1 APD 1 Glycyrrhiza 1 Taxol 1 Estrogens 1 ADM 1 -deoxyadenosine 1 BLM 1 more...

Enzyme proteasome 171 mitogen-activated protein kinase 42 lipoprotein lipase 40 renin 29 AMP-activated protein kinase 27 thymidine phosphorylase 27 protein kinase 24 ERK 22 caspase-3 19 superoxide dismutase 16 alkaline phosphatase 16 AMPK 14 AMPK 14 catalase 14 hormone-sensitive lipase 14 ATPase 12 NO synthase 11 alanine aminotransferase 11 creatine kinase 11 protein kinase C 10 focal adhesion kinase 10 lipase 9 aspartate aminotransferase 9 citrate synthase 9 adenylate cyclase 8 RNA polymerase 8 cathepsin B 8 phosphoenolpyruvate carboxykinase 7 luciferase 7 pyruvate dehydrogenase 7 CPT 7 phosphoenolpyruvate carboxykinase 7 PARP 7 phosphoenolpyruvate carboxykinase 7 trypsin 7 ACE 7 lactate dehydrogenase 6 pyruvate dehydrogenase 6 phosphatidylinositol 3-kinase 6 phosphodiesterase 6 glutathione peroxidase 6 IKK 6 MEK 6 pyruvate dehydrogenase 6 LPL 5 PDK1 5 ACS 5 cytochrome oxidase 5 cathepsin D 5 complex I 5 succinate dehydrogenase 5 peroxidase 5 collagenase 5 lipoxygenase 5 RNase 4 chymotrypsin 4 factor D 4 ornithine decarboxylase 4 RNase 4 GSK 4 transcriptase 4 aldose reductase 4 acid phosphatase 4 hyaluronidase 4 elastase 4 caspase-8 3 xanthine oxidase 3 CD10 3 reverse transcriptase 3 phosphoinositide 3-kinase 3 NADPH oxidase 3 BAT 3 diamine oxidase 3 calcineurin 3 cathepsin L 3 phospholipase C 3 hyaluronidase 3 tyrosine hydroxylase 3 NADPH oxidase 3 beta-galactosidase 3 more...

Compound Dec 398 Clin 380 glucose 219 TNF 174 DNA 131 acetate 122 oxygen 110 water 109 calcium 81 nitrogen 79 Cardiol 77 ATP 61 glutamine 52 zinc 50 leucine 50 sulfate 46 arginine 43 sodium 41 Insulin 38 DMAP 38 glycerol 35 nitric oxide 34 tyrosine 34 creatinine 33 vitamin D 30 His 29 hydrazine 29 Phe 28 urea 28 alanine 23 serine 23 phosphate 22 tryptophan 21 Neo 21 iron 20 aldosterone 19 tryptophan 19 Ang II 19 tryptophan 18 tryptophan 18 cysteine 17 Dial 16 cAMP 15 glutamate 15 potassium 14 AMP 14 CO2 13 galactose 13 Indomethacin 13 selenium 13 PGE2 12 lysine 12 NH2 12 Parenteral 11 PGE 11 GSH 11 GSH 11 Pac 11 MAP 10 L-carnitine 10 MDA 10 hydrogen 10 salt 10 phosphorus 9 5-HT 9 DBA 9 threonine 9 barium 9 Glutamine 9 pyrimidine 8 methionine 8 ACTH 8 retinoic acid 8 SDS 8 nitrate 8 pyrimidine 8 CoA 8 valine 8 3-methylhistidine 8 DHA 7 more...

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