Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0006625 (cachexia)
5,650 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

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Human Gene/Protein
RNF141 11.5
MLL/AF6 fusion 10.9
ubiquitin carrier protein E2 10.9
GFRAL 10.6
truncated adenomatous polyposis coli 10.1
sPLA(2)-IID 9.9
MMD2 9.9
C1orf124 9.7
MuRF 9.5
TMEM154 9.5
TSC22D4 9.5
proline/arginine-rich end leucine-rich repeat protein 9.5
brain mitochondrial carrier protein-1 9.5
GASP-2 9.5
HLA-Cw*0702 9.3
ZNF219 9.3
DDX42 9.3
Atrogin-1 9.3
Suppressor of cytokine signaling-2 9.1
SUPV3L1 9.1
MuRF2 9.1
MSS1 9.1
ECGF1 9.1
ZAG 9.1
atrogin-1 9.0
MuRF1 8.8
MNGIE 8.8
OCC-1 8.8
TRIM72 8.7
RING-finger protein 8.7
MYL1 8.7
JM3 8.7
dermcidin 8.6
TNF-a 8.5
STAMBP 8.5
ghrelin receptor 8.5
myostatin 8.4
ACVR2B 8.4
TKTL1 8.4
NPS1 8.4
more...
Disease
Chastek paralysis 12.5
Unresectable Pancreatic Cancer 12.5
Cancer cachexia 12.2
Female hypogonadism 11.5
Periorbital abscess 10.9
Septic endocarditis 10.9
Mitochondrial neurogastrointestinal encephalopathy 10.5
Granulomatous gastritis 10.5
Chronic radiation enteropathy 10.5
Cardiovascular insufficiency 10.5
EPO resistant anemia 10.1
Acute dermatitis 10.1
Idiopathic myocarditis 9.9
Combined small cell carcinoma 9.9
Endogenous lipoid pneumonia 9.9
Walker carcinoma 256 9.8
Eosinophilic gastritis 9.7
Secondary hemochromatosis 9.5
Acquired generalized lipodystrophy 9.3
Protein-losing gastroenteropathy 9.1
Glomeruloid hemangioma 9.1
appetite disorder 9.1
Secondary anemia 9.0
grade III meningioma 8.9
Lewis Lung Carcinoma 8.8
muscular atrophy 8.8
MNGIE 8.8
wasting syndrome 8.8
postvagotomy syndrome 8.8
Neonatal diarrhea 8.8
Chronic arthritis 8.7
Thoracic Disease 8.7
Diabetic amyotrophy 8.6
skin hyperkeratosis 8.6
Diencephalic syndrome 8.6
wasting 8.5
muscle cancer 8.5
Hepatic venous outflow obstruction 8.4
Acquired renal cystic disease 8.3
Myeloid metaplasia 8.3
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Symptom
cachexia 12.5
Unexplained abdominal pain 9.3
Muscle fibrosis 9.1
anorexia 8.4
breast hyperplasia 7.3
inanition 7.2
asthenia 6.8
emaciation 6.7
Gasping 6.6
decreased appetite 6.4
aphagia 6.4
Skin symptoms 6.4
feeling tired 6.2
adipsia 5.9
abdominal fullness 5.8
Musculoskeletal symptoms 5.7
phosphatemia 5.7
pneumaturia 5.3
generalized rash 5.3
night sweats 5.0
scaly skin 5.0
prostration 4.9
hypoproteinemia 4.9
hepatosplenomegaly 4.9
chyluria 4.9
lethargy 4.8
cancer pain 4.8
abnormal breathing 4.7
starvation 4.7
ophthalmoplegia 4.7
loss of balance 4.6
splenomegaly 4.5
stomach pain 4.5
fatigue 4.5
weakness 4.4
nausea and vomiting 4.4
nasal discharge 4.4
clumsiness 4.4
polydipsia 4.4
nausea 4.3
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Drug
Mecasermin rinfabate 9.7
Thalomid 9.3
Citrus unshiu peel 8.4
Ponalrestat 8.1
Nabilone 7.8
Zaltoprofen 7.7
Hoelen 7.1
Cimaterol 7.1
Somatropin 6.9
Trental 6.8
RPH 6.7
Benzylamine 6.6
GHRP 6.5
Activin 5.7
Pepstatin 5.5
Aliskiren 5.4
Vanilla 5.3
IL-11 5.3
Bezafibrate 5.3
Trabectedin 5.3
Mirtazapine 5.2
Gemzar 4.9
Bactrim 4.8
Mitomycin-C 4.8
DMAP 4.6
Clodronate 4.5
CDX 4.5
Cobalamin 4.4
Epoetin 4.4
Rosiglitazone 4.4
Growth hormone 4.3
Growth hormone 4.2
Gastro 4.2
Serum albumin 4.2
Duloxetine 4.2
Perindopril 4.1
CDX 4.0
Limonene 4.0
Trimethoprim-sulfamethoxazole 3.9
Xanthium 3.8
more...
Enzyme
thymidine phosphorylase 7.2
cholesterol 25-hydroxylase 7.0
MSAS 6.6
endo-alpha-N-acetylgalactosaminidase 6.3
STK2 5.9
3-oxoacid CoA-transferase 5.9
factor D 5.7
alpha-N-acetylglucosaminidase 5.6
calpain 3 5.2
hormone-sensitive lipase 5.2
glycine N-methyltransferase 5.1
betaine-homocysteine methyltransferase 5.1
proteasome 5.1
lipoprotein lipase 5.0
branched-chain alpha-keto acid dehydrogenase 4.9
methionine synthase reductase 4.8
calpain 3 4.7
branched-chain aminotransferase 4.6
p80 4.4
LPL 4.4
BAT 4.3
dihydropyrimidinase 4.3
neutral sphingomyelinase 4.1
cathepsin H 3.9
cathepsin C 3.9
GLO 3.8
m-calpain 3.8
dihydropteridine reductase 3.8
PDK1 3.7
AMPK 3.6
caspase-6 3.6
AMP-activated protein kinase 3.5
citrate synthase 3.5
caspase-6 3.5
cathepsin B 3.4
isopeptidase 3.3
pyruvate dehydrogenase 3.3
pyruvate dehydrogenase 3.3
serine hydroxymethyltransferase 3.3
phosphoenolpyruvate carboxykinase 3.2
more...
Compound
2,4-dichlorophenylalanine 12.5
3,4-dichlorophenylalanine 10.5
Patuletin 9.9
Megestrol 9.3
Tetrahydroberberine 8.9
Tetrahydroberberine 8.9
Hydrazine sulfate 8.6
L-Proline, 8.3
Pyrvinium 8.2
Oxymetholone 7.9
DMAP 7.6
Pyrantel 7.4
Melarsoprol 7.1
C10H16 7.1
3-hydroxyisovaleric acid 7.0
Cyproheptadine 6.8
Eflornithine 6.6
Formoterol 6.6
Benzylamine 6.6
Adenine arabinoside 6.3
Imperatorin 6.2
Oleoylethanolamide 6.2
Hydromorphone 6.1
Elan 5.9
3-methylhistidine 5.8
Parthenolide 5.8
Lentinan 5.8
NIX 5.7
methyl butyrate 5.7
undecanoic acid 5.6
undecanoic acid 5.6
Elan 5.6
undecanoic acid 5.6
Eicosapentaenoic acid 5.6
Tegafur 5.6
Parthenolide 5.6
Mirtazapine 5.4
Conjugated linoleic acid 5.4
N-methylnicotinamide 5.4
WY-14,643 5.4
more...