Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0006625 (cachexia)
5,650 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
cytokine 399
Sep 366
insulin 277
tumor necrosis factor 258
IL-6 226
ubiquitin 214
ghrelin 201
muscle protein 183
TNF 174
Mol 173
proteasome 170
leptin 148
interleukin-6 146
growth hormone 144
cage 140
myostatin 131
TNF-alpha 113
Ghrelin 93
gut 80
albumin 79
IL-1 78
Walker 70
atrogin-1 68
C-reactive protein 67
TNF-a 61
lipopolysaccharide 61
ATP 61
Tumor necrosis factor 56
She 55
mTOR 52
glycoprotein 52
tumor necrosis factor alpha 51
epididymal 49
neuropeptide Y 47
GHRP 46
interferon 46
Cytokine 45
ghrelin receptor 45
androgen receptor 45
lipoprotein lipase 40
more...
Disease
cancer 2503
tumor 1153
muscular atrophy 648
wasting 526
malnutrition 373
obesity 297
heart failure 296
Cancer cachexia 257
tumor growth 257
adenocarcinoma 207
anemia 204
diabetes 179
AIDS 179
chronic obstructive pulmonary disease 147
sepsis 144
carcinoma 140
metastases 134
sepsis 133
depression 131
HIV 114
pancreatic cancer 111
lung cancer 111
wasting syndrome 100
hepatocellular carcinoma 86
rheumatoid arthritis 84
breast cancer 81
congestive heart failure 75
sarcoma 75
lung carcinoma 70
immunodeficiency 69
metabolic syndrome 69
anorexia nervosa 68
tumor progression 65
hypercalcemia 64
renal failure 63
arthritis 60
chronic disease 60
malabsorption 57
osteoporosis 57
colorectal cancer 56
more...
Symptom
cachexia 5650
anorexia 799
fatigue 201
pain 182
weakness 147
starvation 113
diarrhea 108
dyspnea 87
nausea 83
vomiting 74
asthenia 53
splenomegaly 40
abdominal pain 39
nausea and vomiting 36
constipation 35
lethargy 28
hepatosplenomegaly 23
Ill 22
emaciation 20
hunger 20
overweight 20
anesthesia 20
seizures 19
decreased appetite 18
ataxia 18
hepatomegaly 18
cough 16
exhaustion 15
cancer pain 15
ophthalmoplegia 15
regurgitation 13
hypothermia 12
spasticity 12
insomnia 12
discomfort 11
headache 11
respiratory distress 11
polyuria 10
discomfort 10
bone pain 9
more...
Drug
IFN-gamma 39
Cardiovasc 24
IL-2 20
Dial 16
Activin 16
ROS 14
Indomethacin 13
Dermatol 12
Growth hormone 11
MAP 10
Growth hormone 10
GHRP 9
Spectrum 9
IL-11 8
EPA 8
lysine 7
Monit 7
vitamin E 7
CSF 6
Angiotensin II 6
CTX 6
Adriamycin 5
DMAP 5
niacin 4
Albumin 4
NADH 4
CPT-11 4
Serum albumin 4
AZT 4
AZT 4
citric acid 4
9-THC 4
lactose 4
Ginseng 3
Meth 3
Glycerol 3
Trental 3
Bifidobacterium 3
CCL 3
Asthma 3
more...
Enzyme
proteasome 171
mitogen-activated protein kinase 42
lipoprotein lipase 40
renin 29
thymidine phosphorylase 27
AMP-activated protein kinase 27
protein kinase 24
ERK 22
caspase-3 19
alkaline phosphatase 16
superoxide dismutase 16
AMPK 14
catalase 14
AMPK 14
hormone-sensitive lipase 14
ATPase 12
alanine aminotransferase 11
creatine kinase 11
NO synthase 11
focal adhesion kinase 10
protein kinase C 10
citrate synthase 9
lipase 9
aspartate aminotransferase 9
cathepsin B 8
adenylate cyclase 8
RNA polymerase 8
CPT 7
pyruvate dehydrogenase 7
luciferase 7
trypsin 7
phosphoenolpyruvate carboxykinase 7
PARP 7
phosphoenolpyruvate carboxykinase 7
phosphoenolpyruvate carboxykinase 7
ACE 7
phosphodiesterase 6
lactate dehydrogenase 6
MEK 6
IKK 6
more...
Compound
Dec 398
Clin 380
glucose 219
TNF 174
DNA 131
acetate 122
oxygen 110
water 109
calcium 81
nitrogen 79
Cardiol 77
ATP 61
glutamine 52
zinc 50
leucine 50
sulfate 46
arginine 43
sodium 41
Insulin 38
DMAP 38
glycerol 35
nitric oxide 34
tyrosine 34
creatinine 33
vitamin D 30
His 29
hydrazine 29
Phe 28
urea 28
serine 23
alanine 23
phosphate 22
tryptophan 21
Neo 21
iron 20
aldosterone 19
tryptophan 19
Ang II 19
tryptophan 18
tryptophan 18
more...