Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0006625 (
cachexia
)
5,650
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
cytokine
399
Sep
366
insulin
277
tumor necrosis factor
258
IL-6
226
ubiquitin
214
ghrelin
201
muscle protein
183
TNF
174
Mol
173
proteasome
170
leptin
148
interleukin-6
146
growth hormone
144
cage
140
myostatin
131
TNF-alpha
113
Ghrelin
93
gut
80
albumin
79
IL-1
78
Walker
70
atrogin-1
68
C-reactive protein
67
TNF-a
61
lipopolysaccharide
61
ATP
61
Tumor necrosis factor
56
She
55
mTOR
52
glycoprotein
52
tumor necrosis factor alpha
51
epididymal
49
neuropeptide Y
47
GHRP
46
interferon
46
Cytokine
45
ghrelin receptor
45
androgen receptor
45
lipoprotein lipase
40
more...
Disease
cancer
2503
tumor
1153
muscular atrophy
648
wasting
526
malnutrition
373
obesity
297
heart failure
296
Cancer cachexia
257
tumor growth
257
adenocarcinoma
207
anemia
204
diabetes
179
AIDS
179
chronic obstructive pulmonary disease
147
sepsis
144
carcinoma
140
metastases
134
sepsis
133
depression
131
HIV
114
pancreatic cancer
111
lung cancer
111
wasting syndrome
100
hepatocellular carcinoma
86
rheumatoid arthritis
84
breast cancer
81
congestive heart failure
75
sarcoma
75
lung carcinoma
70
immunodeficiency
69
metabolic syndrome
69
anorexia nervosa
68
tumor progression
65
hypercalcemia
64
renal failure
63
arthritis
60
chronic disease
60
malabsorption
57
osteoporosis
57
colorectal cancer
56
more...
Symptom
cachexia
5650
anorexia
799
fatigue
201
pain
182
weakness
147
starvation
113
diarrhea
108
dyspnea
87
nausea
83
vomiting
74
asthenia
53
splenomegaly
40
abdominal pain
39
nausea and vomiting
36
constipation
35
lethargy
28
hepatosplenomegaly
23
Ill
22
emaciation
20
hunger
20
overweight
20
anesthesia
20
seizures
19
decreased appetite
18
ataxia
18
hepatomegaly
18
cough
16
exhaustion
15
cancer pain
15
ophthalmoplegia
15
regurgitation
13
hypothermia
12
spasticity
12
insomnia
12
discomfort
11
headache
11
respiratory distress
11
polyuria
10
discomfort
10
bone pain
9
more...
Drug
IFN-gamma
39
Cardiovasc
24
IL-2
20
Dial
16
Activin
16
ROS
14
Indomethacin
13
Dermatol
12
Growth hormone
11
MAP
10
Growth hormone
10
GHRP
9
Spectrum
9
IL-11
8
EPA
8
lysine
7
Monit
7
vitamin E
7
CSF
6
Angiotensin II
6
CTX
6
Adriamycin
5
DMAP
5
niacin
4
Albumin
4
NADH
4
CPT-11
4
Serum albumin
4
AZT
4
AZT
4
citric acid
4
9-THC
4
lactose
4
Ginseng
3
Meth
3
Glycerol
3
Trental
3
Bifidobacterium
3
CCL
3
Asthma
3
more...
Enzyme
proteasome
171
mitogen-activated protein kinase
42
lipoprotein lipase
40
renin
29
thymidine phosphorylase
27
AMP-activated protein kinase
27
protein kinase
24
ERK
22
caspase-3
19
alkaline phosphatase
16
superoxide dismutase
16
AMPK
14
catalase
14
AMPK
14
hormone-sensitive lipase
14
ATPase
12
alanine aminotransferase
11
creatine kinase
11
NO synthase
11
focal adhesion kinase
10
protein kinase C
10
citrate synthase
9
lipase
9
aspartate aminotransferase
9
cathepsin B
8
adenylate cyclase
8
RNA polymerase
8
CPT
7
pyruvate dehydrogenase
7
luciferase
7
trypsin
7
phosphoenolpyruvate carboxykinase
7
PARP
7
phosphoenolpyruvate carboxykinase
7
phosphoenolpyruvate carboxykinase
7
ACE
7
phosphodiesterase
6
lactate dehydrogenase
6
MEK
6
IKK
6
more...
Compound
Dec
398
Clin
380
glucose
219
TNF
174
DNA
131
acetate
122
oxygen
110
water
109
calcium
81
nitrogen
79
Cardiol
77
ATP
61
glutamine
52
zinc
50
leucine
50
sulfate
46
arginine
43
sodium
41
Insulin
38
DMAP
38
glycerol
35
nitric oxide
34
tyrosine
34
creatinine
33
vitamin D
30
His
29
hydrazine
29
Phe
28
urea
28
serine
23
alanine
23
phosphate
22
tryptophan
21
Neo
21
iron
20
aldosterone
19
tryptophan
19
Ang II
19
tryptophan
18
tryptophan
18
more...