Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0006625 (
cachexia
)
5,650
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
cytokine
399
Sep
366
insulin
277
tumor necrosis factor
258
IL-6
226
ubiquitin
214
ghrelin
201
muscle protein
183
TNF
174
Mol
173
proteasome
170
leptin
148
interleukin-6
146
growth hormone
144
cage
140
myostatin
131
TNF-alpha
113
Ghrelin
93
gut
80
albumin
79
more...
Disease
cancer
2503
tumor
1153
muscular atrophy
648
wasting
526
malnutrition
373
obesity
297
heart failure
296
Cancer cachexia
257
tumor growth
257
adenocarcinoma
207
anemia
204
AIDS
179
diabetes
179
chronic obstructive pulmonary disease
147
sepsis
144
carcinoma
140
metastases
134
sepsis
133
depression
131
HIV
114
more...
Symptom
cachexia
5650
anorexia
799
fatigue
201
pain
182
weakness
147
starvation
113
diarrhea
108
dyspnea
87
nausea
83
vomiting
74
asthenia
53
splenomegaly
40
abdominal pain
39
nausea and vomiting
36
constipation
35
lethargy
28
hepatosplenomegaly
23
Ill
22
hunger
20
emaciation
20
more...
Drug
IFN-gamma
39
Cardiovasc
24
IL-2
20
Dial
16
Activin
16
ROS
14
Indomethacin
13
Dermatol
12
Growth hormone
11
Growth hormone
10
MAP
10
Spectrum
9
GHRP
9
IL-11
8
EPA
8
vitamin E
7
Monit
7
lysine
7
CSF
6
CTX
6
more...
Enzyme
proteasome
171
mitogen-activated protein kinase
42
lipoprotein lipase
40
renin
29
AMP-activated protein kinase
27
thymidine phosphorylase
27
protein kinase
24
ERK
22
caspase-3
19
alkaline phosphatase
16
superoxide dismutase
16
AMPK
14
AMPK
14
catalase
14
hormone-sensitive lipase
14
ATPase
12
alanine aminotransferase
11
NO synthase
11
creatine kinase
11
protein kinase C
10
more...
Compound
Dec
398
Clin
380
glucose
219
TNF
174
DNA
131
acetate
122
oxygen
110
water
109
calcium
81
nitrogen
79
Cardiol
77
ATP
61
glutamine
52
leucine
50
zinc
50
sulfate
46
arginine
43
sodium
41
DMAP
38
Insulin
38
more...