Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0006142 (breast cancer)
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Human Gene/Protein
PTPRG protein 7.6
TRAF3IP3 protein 7.6
ubiquitin specific protease 2 7.6
chromosome 12 open reading frame 32 7.6
PP14571 7.6
ZNF404 7.6
EPHA10 protein 7.6
TENSIN 7.6
INTS4L1 7.6
SH3-domain binding protein 5 (BTK-associated) 7.6
CRKRS 7.6
PTCD3 protein 7.6
nucleolar protein 12 7.6
CEGP1 7.6
thymosin beta 4, X-linked 7.6
zinc finger protein 365 7.6
TBP-associated factor 172 7.6
C16orf3 7.6
NBPF10 7.6
six-transmembrane epithelial antigen of prostate 2 7.6
phosphatidylinositol glycan anchor biosynthesis, class X 7.6
Sushi domain-containing protein 3 7.6
KIAA1024 7.6
BCDIN3 domain containing 7.6
HEATR6 7.6
FLOT2 protein 7.6
HTF9C 7.6
seven span transmembrane protein 7.6
Protein tyrosine phosphatase gamma 7.6
V-myc myelocytomatosis viral oncogene homolog 7.6
OR2A1 7.6
RHOGDI 7.6
ZNF526 7.6
DNCI2 7.6
TMEM184B 7.6
PAX interacting protein 1 7.6
FLJ39609 7.6
ZNF218 7.6
chromosome 6 open reading frame 106 7.6
ECTACC 7.6
C21orf34 7.6
interferon gamma receptor beta chain 7.6
glioma tumor suppressor candidate region gene 2 7.6
growth arrest-specific 11 7.6
ZNF565 7.6
TGF-beta kinase 7.6
kallikrein-related peptidase 15 7.6
C7orf34 7.6
mitochondrial ribosomal protein L32 7.6
SAX3 7.6
ZNF584 7.6
WD repeat domain 34 7.6
ZBTB12 7.6
NXPH2 7.6
DKFZp762B245 7.6
C1orf51 7.6
C8orf31 7.6
BCAR2 7.6
C17orf71 7.6
hCLA-iso 7.6
AMPH1 7.6
FBXL8 7.6
PRPF38B 7.6
TNFSF13 protein 7.6
Stromal interaction molecule 2 7.6
MRIP-1 7.6
zinc finger protein 668 7.6
SNX24 7.6
THUMP domain-containing protein 1 7.6
IQ motif and ubiquitin domain containing 7.6
PRO2605 7.6
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme 7.6
LDLRAD1 7.6
TMEM14A 7.6
Inhibitor of growth protein 2 7.6
HSPC194 7.6
C6orf211 7.6
CA5B 7.6
MORC family CW-type zinc finger 4 7.6
ZMYM6 7.6
more...
Disease
Fat necrosis of breast 7.6
Contralateral breast cancer 7.6
Other thyroid disorders 7.6
hormone related cancer 7.6
Malignant pleurisy 7.6
Malignant esophageal stricture 7.6
Tamoxifen retinopathy 7.6
Artificial menopause 7.6
Invasive Breast Cancer 7.6
Metastasis to gastrointestinal tract 7.6
cystorrhagia 7.6
Breast Lymphoma 7.6
Chest wall mass 7.6
chronic cystic breast 7.6
Mucinous breast cancer 7.6
breast cancer 7.6
Bacterial paronychia 7.6
stage IIIC breast cancer 7.6
Treatment related acute myeloid leukemia 7.6
Postrenal failure 7.6
Blunt duct adenosis 7.6
Chronic cystic mastitis 7.6
Unknown Primary Tumors 7.6
Breast cellulitis 7.6
stage I mantle cell lymphoma 7.6
Sexual frustration 7.6
involution; breast 7.6
breast cancer stage 7.4
pregnancy and breast cancer 7.4
Hereditary Breast Cancer 7.4
in situ breast cancer 7.4
BRCAX 7.4
stage I breast cancer 7.3
bilateral breast cancer 7.3
Metaplastic squamous cell carcinoma 7.2
Infiltrating duct carcinoma 7.2
HER-2 positive breast cancer 7.2
stage II breast cancer 7.1
cutaneous breast cancer 7.0
stage III breast cancer 7.0
inflammatory breast cancer 7.0
Invasive Carcinoma 7.0
Estrogenic effect 6.9
Sclerosing adenosis 6.9
benign proliferative breast disease 6.9
medullary breast carcinoma 6.9
metastatic breast cancer 6.9
recurrent breast cancer 6.9
Ductal carcinoma 6.9
stage IIIA breast cancer 6.8
stage IIIB breast cancer 6.8
Lipid-rich carcinoma 6.8
MDD2 6.8
MCF 6.8
invasive lobular breast carcinoma 6.7
Axillary metastases 6.7
infiltrating ductal carcinoma 6.7
bilateral cancer 6.7
ductal carcinoma in situ 6.7
Ovarian hypofunction 6.6
Pulmonary necrosis 6.6
Peritoneal carcinoma 6.6
Invasive cervix cancer 6.6
Environmental Cancer 6.6
Glycogen-rich carcinoma 6.6
Hyposideremia 6.6
parathyroid chief cell adenoma 6.6
Nipple retraction 6.6
Fear of weight gain 6.6
BONE DESTRUCTION 6.6
Occult carcinoma 6.6
Fibrous mastopathy 6.6
Breast fibrosis 6.6
Neoplastic pericarditis 6.6
Iatrogenic lymphedema 6.6
Giant cell sarcoma 6.6
endometrial cancer, stage 6.6
FANCN 6.6
ductal carcinoma 6.6
Sentinel node 6.6
more...
Symptom
Serous nipple discharge 7.6
male breast mass 7.6
Delayed menopause 7.6
retracted nipple 7.0
breast hyperplasia 6.8
Perimenopausal symptoms 6.6
Bloody discharge 6.2
nipple discharge 6.2
nipple discharge 6.2
Chest wall pain 6.0
Cancer Fatigue 5.8
axillary pain 5.8
hot flashes 5.7
menopausal symptoms 5.6
bleeding in breast 5.6
hot flushes 5.5
Breast pain 5.4
Post-mastectomy pain 5.3
Cyclical mastalgia 5.3
Acute vomiting 5.3
Metastatic bone pain 5.3
Vaginal dryness 5.3
peau d'orange 5.1
mastalgia 5.1
peri-menopausal 4.9
Bloody nipple discharge 4.8
Monoparesis 4.8
High weight 4.3
joint symptom 4.3
Truncal ataxia 4.3
Skin thickening 4.2
rib pain 4.2
localized rash 4.2
feeling worried 4.2
GU symptoms 4.2
bone pain 4.1
ovulatory bleeding 4.0
hypertrophic breast 4.0
Early complication 3.9
leg cramps 3.9
No vomiting 3.8
Musculoskeletal symptoms 3.7
Climacteric symptoms 3.7
Shoulder stiffness 3.6
Breast tenderness 3.5
loss of feeling 3.5
irregular bleeding 3.3
Kussmaul's sign 3.2
skin impairment 3.2
vaginal pain 3.1
RNA marker 3.0
emotional shock 3.0
night sweats 3.0
physical symptom 3.0
Scratch 3.0
Localized pain 2.9
Signs and Symptoms 2.8
Flu-like symptoms 2.8
Multiple symptoms 2.8
feeling sick 2.8
upset stomach 2.8
nausea and vomiting 2.7
vaginal itching 2.5
asthenia 2.5
reproductive problem 2.5
arm pain 2.5
nausea 2.4
finger pain 2.4
Sister Mary Joseph's nodule 2.4
No toxic effect 2.3
photopsia 2.2
sialectasis 2.1
Foot pain 2.1
stomach cramps 2.0
generalized abdominal pain 2.0
arthralgia 2.0
lump in the neck 2.0
cardialgia 1.9
Beau's lines 1.9
overweight 1.9
more...
Drug
Lisuride maleate 7.6
Miproxifene phosphate 7.6
Pexeva 7.6
Poliglusam 7.6
Dezaguanine 7.6
Femara 7.3
Arimidex 7.3
Aromasin 7.3
Fareston 7.2
Fareston 7.1
Fulvestrant 7.0
Afema 6.9
Ixabepilone 6.9
Herceptin 6.8
Pertuzumab 6.8
Pueraria root 6.6
Drostanolone 6.6
Boniva 6.6
Affinitak 6.6
Diisopropylamine dichloroacetate 6.6
Rogletimide 6.6
Isosulfan blue 6.6
Tykerb 6.5
4-Hydroxytamoxifen 6.4
CEA-Scan 6.3
Tanaproget 6.3
Idoxifene 6.3
Efaproxiral 6.2
Evista 6.2
Epidoxorubicin 6.1
Raloxifene 6.1
Vorozole 6.0
Zosuquidar trihydrochloride 6.0
Aredia 5.9
Fadrozole hydrochloride 5.9
Lasofoxifene tartrate 5.6
Amdray 5.6
Tibolone 5.6
Vinorelbine 5.5
Actonel 5.4
Taxotere 5.3
Telavancin hydrochloride 5.3
Mudanpi 5.3
Mubritinib 5.3
Zoledronic acid 5.3
Motexafin lutetium 5.3
Bazedoxifene acetate 5.3
Thiodigalactoside 5.3
Xeloda 5.3
Zoladex 5.3
Zoladex 5.3
Docetaxel 5.2
Navelbine 5.2
Bonefos 5.1
Glutethimide 5.1
Chirocaine 5.0
M-AMSA 5.0
Chirocaine 5.0
Lumiliximab 5.0
Lysophosphatidylglycerol 5.0
Tartronate 5.0
ADR 5.0
Zoledronic acid 5.0
Estrogens 5.0
Talabostat 4.8
Apaziquone 4.8
Mepitiostane 4.8
Ibandronate 4.8
Alimta 4.8
Novantrone 4.8
Lonafarnib 4.7
Menogaril 4.7
Gemzar 4.7
DM1 4.6
Rubitecan 4.6
Succinobucol 4.6
Taxol 4.6
Triptorelin 4.6
Ortho Tri-Cyclen 4.6
Abarelix 4.5
more...
Enzyme
EC 1.1.1.52 7.6
ChEH 7.0
EC 2.4.99.3 6.6
kallikrein 9 6.0
kallikrein 14 5.8
kallikrein 10 5.8
stromelysin-3 5.1
estrogen sulfotransferase 5.0
complement subcomponent C1r 4.8
isoflavone 2'-hydroxylase 4.6
STK11 4.6
caspase-7 4.5
caspase-7 4.5
prostase 4.5
STK13 4.5
ERK 4.4
ALDH 4.4
Tpa 4.3
N,O-acetyltransferase 4.3
matrilysin-2 4.3
carnitine O-octanoyltransferase 4.3
cathepsin D 4.2
GK2 4.2
AICAR transformylase 4.1
estrogen sulfotransferase 4.1
matrix metalloproteinase 10 4.1
phosphatidylinositol-4,5-bisphosphate 3-kinase 4.1
PARP 4.0
phosphoglycerate dehydrogenase 4.0
aspartyl aminopeptidase 3.9
thymidine phosphorylase 3.9
HK3 3.8
GalT-4 3.8
GD3 synthase 3.8
caspase-10 3.7
17beta-HSD 3.7
matriptase 3.7
cancer procoagulant 3.7
collagenase 3 3.7
histone demethylase 3.7
steroid 5-alpha-reductase 3.6
gamma-glutamylcyclotransferase 3.6
proteasome ATPase 3.6
phosphoethanolamine cytidylyltransferase 3.6
matriptase 3.6
choline kinase 3.6
caspase-10 3.6
neurosin 3.6
MIPP 3.5
dihydropyrimidine dehydrogenase 3.5
inositol polyphosphate 4-phosphatase 3.5
chondro-4-sulfatase 3.5
HPRP 3.5
legumain 3.4
nepenthesin 3.4
XMT 3.4
isochorismatase 3.4
urokinase-type plasminogen activator 3.4
17beta-HSD 3.4
caspase-9 3.4
cdc2 3.3
P-glycoprotein 3.3
hydroxyprostaglandin dehydrogenase 3.3
lysyl oxidase 3.3
neuropsin 3.3
sulfatase 3.3
hepsin 3.2
hepsin 3.2
DACS 3.2
histone-lysine N-methyltransferase 3.2
cytosine deaminase 3.2
eEF2 kinase 3.2
STK4 3.2
caspase-6 3.2
chondroitin 4-sulfotransferase 3.2
phosphoinositide 3-kinase 3.1
caspase-6 3.1
caspase-8 3.1
5,10-methenyltetrahydrofolate synthetase 3.1
inositol 3-kinase 3.1
more...
Compound
(-)-Sativan 7.6
1,3-thiazinan-5-one 7.6
methyl hexopyranosiduronic acid 7.6
4-chloro-1H-indole-2,3-dione 7.6
Bowdichione 7.6
2,2',3',4',6'-Pentachloro-4-biphenylol 7.6
C8H6O2 7.6
S-Acetylmercaptosuccinic anhydride 7.6
10-oxodecanoic acid 7.6
N-(3-methoxyphenyl)hydrazinecarbothioamide 7.6
Tributyltin bromide 7.6
NSC 57148 7.6
1,2-diphenyl-1-butanol 7.6
2-phenylpyrrolo[2,1-a]isoquinoline 7.6
12-Deoxyphorbol 13-palmitate 7.6
C8H6O2 7.6
Exemestane 7.3
Anastrozole 7.2
Droloxifene 6.9
Tamoxifen 6.8
Tamoxifen 6.8
ICI 164384 6.7
Clionasterol 6.6
5-nitroso-8-quinolinol 6.6
C6H10O6 6.6
trans-4-Hydroxystilbene 6.6
D-Mannuronic acid 6.6
C17H12O6 6.6
4-quinolinecarbaldehyde 6.6
C16H16O3 6.6
N-(2-phenylethyl)acetamide 6.6
C 494 6.6
C6H10O6 6.6
C18H13N5O 6.6
6-phenyl-1,3,5-triazine-2,4-diamine 6.6
undecanamide 6.6
N,N-dimethylbenzenesulfonamide 6.6
2,2',3,3',4',5,5'-heptachloro-4-biphenylol 6.6
Spiroplatin 6.6
4,5-dichloro-1H-imidazole 6.6
dibenzo[b,f]thiepine 6.6
Abyssinone V 6.6
DANU 6.6
C6H10O6 6.6
C6H10O6 6.6
5,8-isoquinolinedione 6.6
C6H10O6 6.6
C6H10O6 6.6
C6H10O6 6.6
AD-143 6.6
C6H10O6 6.6
C6H10O6 6.6
MDA 6.6
Toremifene 6.6
Letrozole 6.5
Promegestone 6.5
Hydroxytamoxifen 6.4
4-OHT 6.4
CI-941 6.3
Triphenylethylene 6.3
Raloxifene 6.2
Patent blue 6.2
IDC 6.1
Procyanidin B4 6.0
Oxyphenisatin 6.0
ergosta-7,22-dien-3-ol 6.0
Dipalmitoylphosphatidic acid 6.0
C19H18O8 6.0
delta-Tocotrienol 6.0
4-(benzyloxy)benzaldehyde 6.0
C6H10O6 6.0
2-Acetylaminophenanthrene 6.0
C24H24 6.0
N-(1-phenylethyl)acetamide 6.0
4-quinolinecarbaldehyde 6.0
allyl butyrate 6.0
ethyl 2-cyano-3-ethoxyacrylate 6.0
NSC 337766 6.0
Drostanolone 6.0
C6H10O6 6.0
more...