Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0006142 (
breast cancer
)
160,383
document(s) hit in 31,850,051 MEDLINE articles (0.08 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
estrogen receptor
11340
Sep
9613
Mol
8817
HER2
7340
p53
5022
BRCA1
4465
progesterone receptor
4298
epidermal growth factor receptor
4171
aromatase
3301
hormone receptor
2709
BRCA2
2591
nodal
2280
AKT
1715
Bcl-2
1639
PI3K
1579
neu
1547
erbB-2
1507
caspase-3
1495
E-cadherin
1479
oestrogen receptor
1389
mTOR
1380
cyclin D1
1353
EGFR
1353
cytokine
1338
insulin
1324
tyrosine kinase
1315
p21
1277
Ki-67
1265
MRI
1199
MAPK
1182
epidermal growth factor
1138
vascular endothelial growth factor
1123
She
1097
ERK
1038
PARP
1035
CD44
1028
collagen
1019
histone
984
NMR
982
catenin
905
estrogen receptor alpha
840
ERK1
834
cage
805
PTEN
793
ATP
756
prolactin
740
VEGF
725
androgen receptor
710
p38
700
EGF
690
matrix metalloproteinase
672
P-glycoprotein
671
TNM
665
Aromatase
661
Estrogen receptor
643
vimentin
637
STAT3
627
CD24
625
ERBB2
609
proteasome
597
glycoprotein
595
pS2
585
insulin-like growth factor
585
IL-6
582
ACS
581
CD8
580
receptor tyrosine kinase
575
p27
574
MMP-9
570
TNF
557
CDK4
546
PIK3CA
545
fibronectin
516
ubiquitin
514
UTR
504
endoplasmic reticulum
501
ESR1
493
tumor necrosis factor
484
urokinase-type plasminogen activator
479
caspase-9
478
more...
Disease
breast cancer
160383
cancer
73177
tumor
44093
MCF
15455
metastases
10569
carcinoma
9634
tumor growth
5661
tumorigenesis
4758
metastatic breast cancer
4590
tumor progression
4330
carcinogenesis
4139
lung cancer
3608
ovarian cancer
3583
prostate cancer
3352
melanoma
2756
primary tumor
2504
colorectal cancer
2105
ductal carcinoma in situ
1948
adenocarcinoma
1850
ductal carcinoma
1777
colon cancer
1773
mammary tumor
1767
obesity
1765
leukemia
1726
bone metastases
1475
endometrial cancer
1421
cervical cancer
1372
gastric cancer
1363
osteoporosis
1276
aggressiveness
1170
hepatocellular carcinoma
1152
diabetes
1082
lymphoma
1017
depression
1014
carcinoma of the breast
941
pancreatic cancer
855
lymphedema
850
non-small cell lung cancer
821
neutropenia
818
cardiovascular disease
783
uterus
769
brain metastases
702
multiple myeloma
694
Hodgkin's disease
656
liver cancer
634
invasive cancer
621
ATM
581
squamous cell carcinoma
571
hypertension
562
lung metastases
532
renal cell carcinoma
520
tumor angiogenesis
505
liver cancer
501
anemia
496
glioblastoma
492
sarcoma
483
carcinoma of the breast
473
recurrent breast cancer
464
bladder cancer
458
solid tumor
444
retinoblastoma
443
glioma
437
inflammatory breast cancer
435
residual disease
428
Luminal
424
stroke
420
liver metastases
414
epithelial ovarian cancer
406
infiltrating ductal carcinoma
405
lung carcinoma
399
EMT
398
osteosarcoma
388
myelosuppression
386
thrombocytopenia
379
tumor initiation
369
acute myeloid leukemia
367
SCID
358
thyroid cancer
358
renal cancer
352
neuroblastoma
348
more...
Symptom
pain
1757
fatigue
837
nausea
644
overweight
482
vomiting
479
menopausal symptoms
409
diarrhea
400
anesthesia
324
nausea and vomiting
324
bone pain
278
hot flashes
277
hot flushes
277
discomfort
235
headache
200
dyspnea
199
nipple discharge
199
nipple discharge
188
starvation
187
discomfort
180
weakness
167
erythema
153
anorexia
151
arthralgia
141
insomnia
113
collapse
97
constipation
93
myalgia
92
abdominal pain
91
cough
85
analgesia
83
numbness
82
cachexia
81
asthenia
76
back pain
71
paresthesia
65
mastalgia
65
ataxia
56
stigma
53
cancer pain
53
seizures
52
exhaustion
51
sleepiness
51
night sweats
49
chills
48
dizziness
48
Ill
47
chest pain
46
HSA
42
shortness of breath
36
acidity
34
hopelessness
33
angina
31
flushing
30
peri-menopausal
28
thinning
27
low back pain
27
lethargy
27
vertigo
23
myoclonus
22
memory loss
20
masculinization
20
breast hyperplasia
20
shoulder pain
19
irregular bleeding
19
respiratory distress
18
cerebellar ataxia
18
Depressive symptoms
17
splenomegaly
17
tremor
17
acute pain
17
peau d'orange
16
epigastric pain
16
neck pain
16
Scratch
16
agitation
16
syncope
15
Breast pain
15
distraction
15
arm pain
14
decreased appetite
14
more...
Drug
Herceptin
1323
ICI
608
MAP
540
lysine
532
ROS
470
Adriamycin
401
Taxol
393
EE2
369
Estrogens
353
ADR
340
Docetaxel
335
CSF
304
CTX
285
ROC
263
Raloxifene
248
G-CSF
244
vitamin E
238
Fulvestrant
234
DM1
199
IL-2
197
Dermatol
193
uPA
171
IFN-gamma
165
Monit
160
ascorbate
140
CTX
133
Paraffin
130
ADM
128
Taxotere
127
Cardiovasc
126
Zoledronic acid
126
Mutagen
119
GEO
119
Bevacizumab
118
ABC
118
Arimidex
116
Gel
116
Zoledronic acid
101
NADH
100
caffeine
95
Vinorelbine
94
Gefitinib
91
Pertuzumab
76
Everolimus
72
Retinoic acid
71
CTX
67
ETS
66
Leaf
61
Zoladex
60
TAT
60
CAM
59
Asn
57
TAC
56
Denosumab
56
MRC
54
Norplant
53
CTC
52
CTC
51
Femara
50
Zoladex
50
NVP
49
Ixabepilone
49
Vitamin E
49
Glutathione
48
ZnO
47
Albumin
47
Tibolone
44
ENT
43
Cetuximab
43
Spectrum
43
Fluorescein
43
Depo-Provera
40
Cremophor EL
38
Bortezomib
38
citric acid
37
PTH
36
DNase I
36
Alliance
34
Imatinib
34
BLM
33
more...
Enzyme
ERK
10031
mitogen-activated protein kinase
3003
luciferase
1470
focal adhesion kinase
1457
protein kinase
1289
caspase-3
1126
PARP
1122
P-glycoprotein
677
proteasome
606
MEK
600
ACS
581
urokinase-type plasminogen activator
562
protein kinase C
484
cdc2
424
reverse transcriptase
418
phosphatidylinositol 3-kinase
412
caspase-9
387
cathepsin D
385
topoisomerase
374
topoisomerase
355
glutathione S-transferase
354
alkaline phosphatase
341
catalase
304
peroxidase
302
caspase-8
298
ATPase
292
AMP-activated protein kinase
283
phosphoinositide 3-kinase
261
RNA polymerase
259
superoxide dismutase
232
lactate dehydrogenase
208
AMPK
202
trypsin
193
collagenase
187
APC
179
DNA methyltransferase
174
AMPK
173
GSK
170
sulfatase
161
MMP
156
aldehyde dehydrogenase
152
aldehyde dehydrogenase
151
aldehyde dehydrogenase
148
aldehyde dehydrogenase
148
aldehyde dehydrogenase
148
RNase
143
calcineurin
140
RNase
137
glutathione peroxidase
137
thymidylate synthase
128
NQO1
126
MDR
125
thymidine kinase
123
alanine aminotransferase
120
IKK
120
prostate-specific antigen
119
thrombin
115
cathepsin B
110
CYP3A4
108
aspartate aminotransferase
108
MAP
105
caspase-7
105
caspase-7
105
demethylase
98
DNA polymerase
97
ALDH
93
matrix metalloproteinase 9
92
glyceraldehyde-3-phosphate dehydrogenase
91
phospholipase C
89
ornithine decarboxylase
86
NOS
85
plasmin
84
dihydrofolate reductase
82
thymidine phosphorylase
76
transcriptase
75
PDK1
75
beta-galactosidase
74
matrix metalloproteinase 2
72
tissue plasminogen activator
71
hyaluronidase
68
more...
Compound
DNA
12556
MDA
11788
Dec
10690
Clin
9775
oxygen
2227
Tamoxifen
2083
MTT
2039
Tamoxifen
2027
tyrosine
1528
water
1424
calcium
1390
Estrogen
1363
Estrogen
1360
acetate
1189
glucose
1188
Pac
895
PEG
871
Adriamycin
820
ADR
791
ATP
759
serine
743
lysine
697
phosphate
692
sulfate
683
sodium
664
TNM
663
iron
615
PEG
611
ICI
610
vitamin D
605
ACS
583
ACS
581
arginine
574
retinoic acid
573
bromide
571
TNF
557
cysteine
555
hydrogen
535
methionine
534
ethanol
525
zinc
496
anthracene
483
iodine
461
threonine
448
Estradiol
441
5-FU
440
Paclitaxel
439
Luminal
428
MEK
425
Progesterone
413
copper
399
galactose
368
GSH
341
GSH
341
nitric oxide
336
cAMP
333
nitrogen
314
DBA
305
silver
296
alanine
290
MAP
288
CTX
285
Insulin
278
leucine
273
Docetaxel
253
Raloxifene
248
CAM
248
His
242
DFS
237
hyaluronic acid
231
Curcumin
229
ADP
222
salt
220
phenol
219
selenium
218
methanol
217
glutamine
217
Asp
215
ADP-ribose
215
creatinine
213
more...