Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0006142 (breast cancer)
160,383 document(s) hit in 31,850,051 MEDLINE articles (0.10 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
estrogen receptor 11340
Sep 9613
Mol 8817
HER2 7340
p53 5022
BRCA1 4465
progesterone receptor 4298
epidermal growth factor receptor 4171
aromatase 3301
hormone receptor 2709
BRCA2 2591
nodal 2280
AKT 1715
Bcl-2 1639
PI3K 1579
neu 1547
erbB-2 1507
caspase-3 1495
E-cadherin 1479
oestrogen receptor 1389
mTOR 1380
cyclin D1 1353
EGFR 1353
cytokine 1338
insulin 1324
tyrosine kinase 1315
p21 1277
Ki-67 1265
MRI 1199
MAPK 1182
epidermal growth factor 1138
vascular endothelial growth factor 1123
She 1097
ERK 1038
PARP 1035
CD44 1028
collagen 1019
histone 984
NMR 982
catenin 905
more...
Disease
breast cancer 160383
cancer 73177
tumor 44093
MCF 15455
metastases 10569
carcinoma 9634
tumor growth 5661
tumorigenesis 4758
metastatic breast cancer 4590
tumor progression 4330
carcinogenesis 4139
lung cancer 3608
ovarian cancer 3583
prostate cancer 3352
melanoma 2756
primary tumor 2504
colorectal cancer 2105
ductal carcinoma in situ 1948
adenocarcinoma 1850
ductal carcinoma 1777
colon cancer 1773
mammary tumor 1767
obesity 1765
leukemia 1726
bone metastases 1475
endometrial cancer 1421
cervical cancer 1372
gastric cancer 1363
osteoporosis 1276
aggressiveness 1170
hepatocellular carcinoma 1152
diabetes 1082
lymphoma 1017
depression 1014
carcinoma of the breast 941
pancreatic cancer 855
lymphedema 850
non-small cell lung cancer 821
neutropenia 818
cardiovascular disease 783
more...
Symptom
pain 1757
fatigue 837
nausea 644
overweight 482
vomiting 479
menopausal symptoms 409
diarrhea 400
anesthesia 324
nausea and vomiting 324
bone pain 278
hot flushes 277
hot flashes 277
discomfort 235
headache 200
nipple discharge 199
dyspnea 199
nipple discharge 188
starvation 187
discomfort 180
weakness 167
erythema 153
anorexia 151
arthralgia 141
insomnia 113
collapse 97
constipation 93
myalgia 92
abdominal pain 91
cough 85
analgesia 83
numbness 82
cachexia 81
asthenia 76
back pain 71
mastalgia 65
paresthesia 65
ataxia 56
cancer pain 53
stigma 53
seizures 52
more...
Drug
Herceptin 1323
ICI 608
MAP 540
lysine 532
ROS 470
Adriamycin 401
Taxol 393
EE2 369
Estrogens 353
ADR 340
Docetaxel 335
CSF 304
CTX 285
ROC 263
Raloxifene 248
G-CSF 244
vitamin E 238
Fulvestrant 234
DM1 199
IL-2 197
Dermatol 193
uPA 171
IFN-gamma 165
Monit 160
ascorbate 140
CTX 133
Paraffin 130
ADM 128
Taxotere 127
Cardiovasc 126
Zoledronic acid 126
GEO 119
Mutagen 119
ABC 118
Bevacizumab 118
Gel 116
Arimidex 116
Zoledronic acid 101
NADH 100
caffeine 95
more...
Enzyme
ERK 10031
mitogen-activated protein kinase 3003
luciferase 1470
focal adhesion kinase 1457
protein kinase 1289
caspase-3 1126
PARP 1122
P-glycoprotein 677
proteasome 606
MEK 600
ACS 581
urokinase-type plasminogen activator 562
protein kinase C 484
cdc2 424
reverse transcriptase 418
phosphatidylinositol 3-kinase 412
caspase-9 387
cathepsin D 385
topoisomerase 374
topoisomerase 355
glutathione S-transferase 354
alkaline phosphatase 341
catalase 304
peroxidase 302
caspase-8 298
ATPase 292
AMP-activated protein kinase 283
phosphoinositide 3-kinase 261
RNA polymerase 259
superoxide dismutase 232
lactate dehydrogenase 208
AMPK 202
trypsin 193
collagenase 187
APC 179
DNA methyltransferase 174
AMPK 173
GSK 170
sulfatase 161
MMP 156
more...
Compound
DNA 12556
MDA 11788
Dec 10690
Clin 9775
oxygen 2227
Tamoxifen 2083
MTT 2039
Tamoxifen 2027
tyrosine 1528
water 1424
calcium 1390
Estrogen 1363
Estrogen 1360
acetate 1189
glucose 1188
Pac 895
PEG 871
Adriamycin 820
ADR 791
ATP 759
serine 743
lysine 697
phosphate 692
sulfate 683
sodium 664
TNM 663
iron 615
PEG 611
ICI 610
vitamin D 605
ACS 583
ACS 581
arginine 574
retinoic acid 573
bromide 571
TNF 557
cysteine 555
hydrogen 535
methionine 534
ethanol 525
more...