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Query: UMLS:C0006142 (breast cancer)
 160,383 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

To achieve satisfactory cosmetic results after breast conserving treatment (BCT) of cancer in patients (with small breasts, the association of BCT and bilateral video-assisted augmentation mammoplasty with differentiated prosthesis volume was performed. From January 2001 21 small breast pts with breast cancer (stage T1N0M0) were treated with BCT and immediate trans-axillary video-assisted breast reconstruction with differentiated volumes. In 15 patients sentinel node biopsy was performed and 6 patients required total axillary dissection. Tumor-free margins were confirmed by histological examination. All patients underwent postoperative radiotherapy. Cosmetic results were evaluated through 6 parameters: breast shape with and without underwear, symmetry, mobility, inframammary fold, tenderness. We observed 4 minor complications: seroma3, paresthesia and slight arm weakness. Mini-invasive surgical revision was required in 3 cases due to scar retraction of the prosthesis pocket. Prosthesis volume resulted 30% (range, 0-47%) higher in the affected side. Cosmetic result was positive in 85% of cases (excellent 15%, good 45%, fair 25%). Trans-axillary video-assisted breast mammoplasty with differentiated prosthesis volumes allows to obtain good aesthetic results in small breast patients and to extend BCT indications with a low morbidity rate.
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PMID:[Conservative treatment of breast carcinoma in small breasts: new minimally invasive surgical technique]. 1643 74

The aim of this systematic review was to identify the prevalence and severity of upper limb problems following surgery and radiation for early breast cancer. Additionally, the independent prognostic contribution of radiation, type of breast surgery, type of axillary surgery, age and body mass index (BMI) was evaluated. Searches of electronic databases were conducted to identify articles that reported upper limb and quality of life outcomes after breast cancer surgery and external radiation. Eligible studies for prognosis were longitudinal in design, with > or =95% of patients treated by surgery and radiation that excluded the axilla. Cross-sectional studies were also included for identification of prognostic factors. Where possible, the contribution of independent prognostic factors was analyzed. The review identified 32 relevant studies. Shoulder restriction was reported in between <1% and 67% of participants, lymphedema was reported in between 0 and 34% of participants, shoulder/arm pain was reported in between 9 and 68% of participants and arm weakness was reported in between 9 and 28% of participants. Quality of life was high across studies. Irradiated patients had slightly increased odds of lymphedema (OR = 1.46, 95% CI 1.16-1.84) and shoulder restriction (OR = 1.67, 95% CI 0.98-2.86) compared with non-irradiated patients. For patients undergoing surgery and radiation for breast cancer, the prognosis is good in terms of the upper limb and quality of life. Radiation that excludes the axilla does not appear to be a strong prognostic indicator of adverse upper limb outcomes.
Breast Cancer Res Treat 2008 Jul
PMID:Prognosis of the upper limb following surgery and radiation for breast cancer. 1789 73