Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0005940 (bone disease)
7,459 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
parathyroid hormone 0.006
PTH 0.002
RANKL 0.001
alkaline phosphatase 0.001
osteoprotegerin 0.001
osteocalcin 0.001
RANK 0.001
sclerostin 0.001
chronic renal failure 0.000
OPG 0.000
TNFRSF11A 0.000
TCIRG1 0.000
FGF23 0.000
parathormone 0.000
Dickkopf-1 0.000
tartrate-resistant acid phosphatase 0.000
Sclerostin 0.000
pycnodysostosis 0.000
CLCN7 0.000
Chloride channel 7 0.000
ALPL 0.000
type I collagen 0.000
cathepsin K 0.000
vitamin D receptor 0.000
OSTM1 0.000
Klotho 0.000
ubiquitin carboxy-terminal esterase 0.000
suppression of tumorigenicity 5 0.000
matrilin 4 0.000
calcitonin 0.000
BMD 0.000
EXT2 0.000
MDP 0.000
osteogenic 0.000
DEF8 0.000
sclerostin domain containing 1 0.000
RTDR1 0.000
CTSK protein 0.000
cherubism 0.000
infantile malignant osteopetrosis 0.000
T-cell immune regulator 1 0.000
Parathyroid hormone 0.000
ZNF687 0.000
PDCR 0.000
imiglucerase 0.000
glucocerebrosidase 0.000
parathyroid hormone-related protein 0.000
DC-STAMP 0.000
BGP 0.000
receptor activator of NF-kappaB ligand 0.000
SLC23A3 0.000
RIN3 0.000
JPD 0.000
SCUBE3 0.000
HPT 0.000
DKK1 0.000
Osteocalcin 0.000
AMDHD1 0.000
actin, alpha 2, smooth muscle, aorta 0.000
MCC-2 0.000
ALP 0.000
RUNX2 protein 0.000
TRAP 0.000
osteoclast-associated receptor 0.000
FAM98A 0.000
SHISA3 0.000
ubiquitin thiolesterase 0.000
PHEX 0.000
ARHGEF3 0.000
ARH-77 0.000
collagen 0.000
klotho 0.000
COL4A1 protein 0.000
CSS1 0.000
Talin 1 0.000
ANKH 0.000
type I procollagen 0.000
calcium-sensing receptor 0.000
PTHR2 0.000
PSTPIP2 0.000
more...
Disease
bone disease 1.000
renal osteodystrophy 0.015
osteomalacia 0.010
hyperparathyroidism 0.008
osteoporosis 0.007
bone metastases 0.003
hypercalcemia 0.003
osteodystrophy 0.003
multiple myeloma 0.002
osteitis 0.002
hyperphosphatemia 0.002
PDB 0.002
Adynamic bone disease 0.002
rickets 0.001
osteopetrosis 0.001
vitamin D deficiency 0.001
primary hyperparathyroidism 0.001
Secondary hyperparathyroidism 0.001
Fibrous dysplasia of bone 0.001
Metabolic bone disease 0.001
Fibrous dysplasia 0.001
chronic renal failure 0.001
pathological fracture 0.001
osteosclerosis 0.001
hypophosphatasia 0.001
osteogenesis imperfecta 0.001
Osteopenia of prematurity 0.000
hypercalcemia of malignancy 0.000
Aluminum bone disease 0.000
Brown tumor 0.000
renal disease 0.000
renal failure 0.000
parathyroid hyperplasia 0.000
melorheostosis 0.000
Chronic kidney disease (CKD) 0.000
Gaucher disease 0.000
spinal cord compression 0.000
Pycnodysostosis 0.000
Disappearing bone disease 0.000
Aluminum intoxication 0.000
hyperostosis 0.000
Aluminum-related osteomalacia 0.000
Dysosteosclerosis 0.000
osteopoikilosis 0.000
uremia 0.000
Craniometaphyseal dysplasia 0.000
familial hypophosphatemia 0.000
Hungry bone syndrome 0.000
osteomyelitis 0.000
hypercalciuria 0.000
Primary osteoporosis 0.000
High turnover bone disease 0.000
Echinococcus granulosus infestation 0.000
Structural and functional abnormalities of the kidney 0.000
Osteomesopycnosis 0.000
Neonatal rickets 0.000
OPTA1 0.000
hypoparathyroidism 0.000
metastases 0.000
Renal function disorder 0.000
Alcohol-induced chronic pancreatitis 0.000
Malignant gastrinoma 0.000
Azotemic osteodystrophy 0.000
malabsorption 0.000
nephrolithiasis 0.000
vitamin D-resistant rickets 0.000
cherubism 0.000
monoclonal gammopathy of undetermined significance 0.000
EXT2 0.000
SOST 0.000
age related bone loss 0.000
Calcium deficiency 0.000
GSD 0.000
anemia 0.000
JPD 0.000
osteoporotic fracture 0.000
Medullary nephrocalcinosis 0.000
cancer 0.000
Nonpersistence 0.000
BMD 0.000
more...
Symptom
bone pain 0.004
pain 0.000
joint symptom 0.000
phosphatemia 0.000
hepatosplenomegaly 0.000
Musculoskeletal discomfort 0.000
back pain 0.000
cervical spine dysfunction 0.000
musculoskeletal disability 0.000
weakness 0.000
High weight 0.000
hip pain 0.000
Reticulocytosis 0.000
arthralgia 0.000
thinning 0.000
muscle cramps 0.000
thigh pain 0.000
limb pain 0.000
low back pain 0.000
Inflammatory pain 0.000
prominent nose 0.000
gumma 0.000
disturbed balance 0.000
fatigue 0.000
anal pain 0.000
facial droop 0.000
renal colic 0.000
jaw pain 0.000
chronic back pain 0.000
cancer pain 0.000
splenomegaly 0.000
heel pain 0.000
collapse 0.000
clubbing 0.000
inanition 0.000
Catch 0.000
Decreased activity 0.000
physical symptom 0.000
polyuria 0.000
Fluctuation 0.000
lassitude 0.000
hyperemesis 0.000
elbow pain 0.000
abdominal pain 0.000
seizures 0.000
constipation 0.000
groin pain 0.000
polydipsia 0.000
physical appearance 0.000
Wind 0.000
knee pain 0.000
Spots 0.000
anorexia 0.000
blackout 0.000
hepatomegaly 0.000
hot flashes 0.000
Postoperative pain 0.000
leg pain 0.000
POA 0.000
dental pain 0.000
myalgia 0.000
ankle pain 0.000
paresthesia 0.000
nausea 0.000
diarrhea 0.000
Gastrointestinal symptoms 0.000
ENT 0.000
headache 0.000
cachexia 0.000
rales 0.000
hypotonia 0.000
sciatica 0.000
torticollis 0.000
enuresis 0.000
clonus 0.000
bloating 0.000
distraction 0.000
abdominal discomfort 0.000
wrist pain 0.000
tense 0.000
more...
Drug
PTH 0.002
Zoledronic acid 0.001
Zoledronic acid 0.001
Ibandronate 0.000
Denosumab 0.000
Sevelamer 0.000
Clodronate 0.000
Bonefos 0.000
Aredia 0.000
EHDP 0.000
Dial 0.000
Ceredase 0.000
Zemplar 0.000
Lanthanum carbonate 0.000
Sevelamer hydrochloride 0.000
Cinacalcet 0.000
Cerezyme 0.000
Epimedium herb 0.000
LeukoScan 0.000
Bortezomib 0.000
Etidronate disodium 0.000
Cerezyme 0.000
CTX 0.000
CTX 0.000
Calcifediol 0.000
Actonel 0.000
Teriparatide 0.000
Sevelamer carbonate 0.000
Fosamax 0.000
Rocaltrol 0.000
Alfacalcidol 0.000
APD 0.000
Dilaudid 0.000
CTX 0.000
Risedronate sodium 0.000
Cinacalcet hydrochloride 0.000
Nephron 0.000
Januvia 0.000
Nephron 0.000
DMSA 0.000
Femara 0.000
Revlimid 0.000
Lenalidomide 0.000
Hakka 0.000
Pyridostigmine bromide 0.000
IL-11 0.000
Sodium thiosulfate 0.000
Sodium acetate 0.000
Activin 0.000
Trapidil 0.000
Vindesine 0.000
Vindesine 0.000
Arimidex 0.000
Vitamin K2 0.000
Artesunate 0.000
Vitamin K 0.000
Calcipotriol 0.000
Tenofovir disoproxil fumarate 0.000
Salmon calcitonin 0.000
Tibolone 0.000
SrCl2 0.000
Fragmin 0.000
Maraviroc 0.000
PFT 0.000
ARA-C 0.000
Cytidine 0.000
CED 0.000
metformin hydrochloride 0.000
Zoladex 0.000
Epoetin 0.000
Lactase 0.000
Pregnenolone 0.000
Premarin 0.000
Everolimus 0.000
Myricetin 0.000
Zoladex 0.000
Raloxifene 0.000
PMPA 0.000
HPMPC 0.000
TRM 0.000
more...
Enzyme
alkaline phosphatase 0.001
cathepsin K 0.000
glucocerebrosidase 0.000
MDP 0.000
acid phosphatase 0.000
1-hydroxylase 0.000
prostate-specific antigen 0.000
CCS1 0.000
MIP 0.000
proteasome 0.000
mitogen-activated protein kinase 0.000
20beta-hydroxysteroid dehydrogenase 0.000
ERK 0.000
proline iminopeptidase 0.000
protein farnesyltransferase 0.000
lecithin:retinol acyltransferase 0.000
BBE 0.000
alpha-L-iduronidase 0.000
matrix metalloproteinase 9 0.000
calcineurin 0.000
AGT 0.000
homogentisate 1,2-dioxygenase 0.000
prostate-specific membrane antigen 0.000
dihydropyrimidine dehydrogenase 0.000
lysyl oxidase 0.000
glucosylceramide synthase 0.000
fumarylacetoacetate hydrolase 0.000
renin 0.000
EPT 0.000
type III procollagen 0.000
tryptophanyl-tRNA synthetase 0.000
CEP 0.000
FAST 0.000
lactate dehydrogenase 0.000
PMT 0.000
chymopapain 0.000
chymopapain 0.000
thymidine phosphorylase 0.000
AMP-activated kinase 0.000
CEP 0.000
AST 0.000
prolidase 0.000
collagenase 0.000
caspase-1 0.000
lactase 0.000
transglutaminase 0.000
IKK 0.000
isopeptidase 0.000
matrix metalloproteinase 2 0.000
15-hydroxyprostaglandin dehydrogenase 0.000
urokinase-type plasminogen activator 0.000
farnesyltransferase 0.000
GCA 0.000
ornithine aminotransferase 0.000
PRA 0.000
gamma-glutamyl transpeptidase 0.000
reverse transcriptase 0.000
CPT 0.000
granzyme B 0.000
PAT 0.000
PRE 0.000
CPT 0.000
farnesyltransferase 0.000
alanine aminotransferase 0.000
aspartate aminotransferase 0.000
GSK 0.000
CD10 0.000
caspase-8 0.000
protein kinase 0.000
CPT 0.000
caspase-3 0.000
creatine kinase 0.000
focal adhesion kinase 0.000
RNase T1 0.000
luciferase 0.000
11beta-hydroxysteroid dehydrogenase 0.000
ATPase 0.000
phenylalanine hydroxylase 0.000
5'-nucleotidase 0.000
indoleamine 2,3-dioxygenase 0.000
more...
Compound
vitamin D 0.003
calcium 0.001
phosphorus 0.001
Pamidronate 0.000
phosphate 0.000
aluminum 0.000
Vitamin D 0.000
EHDP 0.000
Dial 0.000
25-dihydroxycholecalciferol 0.000
BMD 0.000
Paricalcitol 0.000
Clin 0.000
25-hydroxycholecalciferol 0.000
creatinine 0.000
ALP 0.000
Doxercalciferol 0.000
Alendronate 0.000
HPT 0.000
Rodan 0.000
Risedronate 0.000
Alendronate 0.000
carbonate 0.000
Deoxypyridinoline 0.000
25-Hydroxyvitamin D 0.000
Angelicin 0.000
Calcitonin 0.000
Calcium carbonate 0.000
phosphoric acid 0.000
Vindoline 0.000
Dilaudid 0.000
CTX 0.000
Sulfuretin 0.000
proline-hydroxyproline 0.000
strontium 0.000
Dec 0.000
Vitamin D3 0.000
TAR 0.000
Minocycline hydrochloride 0.000
Pyridinoline 0.000
BAP 0.000
Novex 0.000
Aluminum hydroxide 0.000
Tetracycline hydrochloride 0.000
Indoxyl sulfate 0.000
Vitamin D3 0.000
Ursodeoxycholic acid 0.000
Glabridin 0.000
Ferric citrate 0.000
Succinylacetone 0.000
Parenteral 0.000
iron 0.000
DMO 0.000
oxalate 0.000
isonicotinic acid 0.000
3-aminobenzoic acid 0.000
DGE 0.000
DGE 0.000
DGE 0.000
Hydroxyproline 0.000
DBM 0.000
Alizarin 0.000
DBM 0.000
nitrogen 0.000
pentosidine 0.000
Geigy 0.000
Sodium acetate 0.000
DFO 0.000
4-hydroxyproline 0.000
4-hydroxyproline 0.000
4-hydroxyproline 0.000
4-hydroxyproline 0.000
4-hydroxyproline 0.000
4-hydroxyproline 0.000
Betulin 0.000
TNF 0.000
BAPN 0.000
Vitamin K 0.000
Gambogic acid 0.000
Collagen 0.000
more...