Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0005940 (bone disease)
7,459 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
parathyroid hormone 855
alkaline phosphatase 680
Sep 447
PTH 274
osteocalcin 270
RANKL 233
collagen 227
chronic renal failure 222
Mol 218
osteoprotegerin 168
osteogenic 124
calcitonin 122
RANK 117
type I collagen 116
cytokine 91
tartrate-resistant acid phosphatase 86
sclerostin 75
insulin 74
MRI 73
vitamin D receptor 73
more...
Disease
bone disease 7459
osteoporosis 1434
cancer 859
multiple myeloma 758
hyperparathyroidism 730
tumor 559
hypercalcemia 493
osteomalacia 489
renal osteodystrophy 390
bone metastases 390
metastases 362
chronic renal failure 347
renal disease 332
PDB 290
renal failure 273
breast cancer 265
diabetes 257
vitamin D deficiency 214
primary hyperparathyroidism 200
anemia 198
more...
Symptom
pain 451
bone pain 313
weakness 83
back pain 53
fatigue 43
hepatosplenomegaly 33
seizures 31
thinning 24
collapse 22
low back pain 22
abdominal pain 19
diarrhea 19
arthralgia 19
headache 18
hip pain 16
anesthesia 15
splenomegaly 13
nausea 12
anorexia 10
vomiting 10
more...
Drug
PTH 278
Dial 168
Zoledronic acid 69
Zoledronic acid 60
CTX 38
CTX 38
CTX 37
Nephron 37
Denosumab 37
Nephron 35
EHDP 23
Ibandronate 21
Bortezomib 20
Clodronate 19
CSF 15
Sevelamer 13
APD 12
Cardiovasc 9
Cinacalcet 9
Teriparatide 8
more...
Enzyme
alkaline phosphatase 680
mitogen-activated protein kinase 61
ERK 57
acid phosphatase 50
cathepsin K 46
MDP 40
proteasome 35
glucocerebrosidase 33
renin 21
prostate-specific antigen 19
calcineurin 18
lactate dehydrogenase 17
protein kinase 16
MIP 14
ATPase 13
reverse transcriptase 12
collagenase 11
focal adhesion kinase 11
luciferase 10
caspase-3 10
more...
Compound
calcium 1602
Clin 1034
vitamin D 850
phosphate 728
Dec 505
phosphorus 445
aluminum 262
creatinine 171
Dial 168
Vitamin D 118
DNA 95
carbonate 93
water 89
sodium 82
glucose 81
iron 81
nitrogen 79
BMD 52
oxygen 50
ALP 45
more...