Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0005940 (
bone disease
)
7,459
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
parathyroid hormone
855
alkaline phosphatase
680
Sep
447
PTH
274
osteocalcin
270
RANKL
233
collagen
227
chronic renal failure
222
Mol
218
osteoprotegerin
168
osteogenic
124
calcitonin
122
RANK
117
type I collagen
116
cytokine
91
tartrate-resistant acid phosphatase
86
sclerostin
75
insulin
74
MRI
73
vitamin D receptor
73
more...
Disease
bone disease
7459
osteoporosis
1434
cancer
859
multiple myeloma
758
hyperparathyroidism
730
tumor
559
hypercalcemia
493
osteomalacia
489
renal osteodystrophy
390
bone metastases
390
metastases
362
chronic renal failure
347
renal disease
332
PDB
290
renal failure
273
breast cancer
265
diabetes
257
vitamin D deficiency
214
primary hyperparathyroidism
200
anemia
198
more...
Symptom
pain
451
bone pain
313
weakness
83
back pain
53
fatigue
43
hepatosplenomegaly
33
seizures
31
thinning
24
collapse
22
low back pain
22
abdominal pain
19
diarrhea
19
arthralgia
19
headache
18
hip pain
16
anesthesia
15
splenomegaly
13
nausea
12
anorexia
10
vomiting
10
more...
Drug
PTH
278
Dial
168
Zoledronic acid
69
Zoledronic acid
60
CTX
38
CTX
38
CTX
37
Nephron
37
Denosumab
37
Nephron
35
EHDP
23
Ibandronate
21
Bortezomib
20
Clodronate
19
CSF
15
Sevelamer
13
APD
12
Cardiovasc
9
Cinacalcet
9
Teriparatide
8
more...
Enzyme
alkaline phosphatase
680
mitogen-activated protein kinase
61
ERK
57
acid phosphatase
50
cathepsin K
46
MDP
40
proteasome
35
glucocerebrosidase
33
renin
21
prostate-specific antigen
19
calcineurin
18
lactate dehydrogenase
17
protein kinase
16
MIP
14
ATPase
13
reverse transcriptase
12
collagenase
11
focal adhesion kinase
11
luciferase
10
caspase-3
10
more...
Compound
calcium
1602
Clin
1034
vitamin D
850
phosphate
728
Dec
505
phosphorus
445
aluminum
262
creatinine
171
Dial
168
Vitamin D
118
DNA
95
carbonate
93
water
89
sodium
82
glucose
81
iron
81
nitrogen
79
BMD
52
oxygen
50
ALP
45
more...