Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0005684 (bladder cancer)
 16,431 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 1016
Mol 806
non-muscle 769
p53 697
pT1 255
caspase-3 208
pTa 206
E-cadherin 189
p21 165
AKT 164
Bcl-2 157
mTOR 156
cytokine 153
FGFR3 152
PI3K 143
cyclin D1 132
epidermal growth factor receptor 128
interferon 128
catenin 125
vascular endothelial growth factor 113
nodal 113
TNM 110
MAPK 109
NAT2 104
TCC 98
GSTM1 98
CD8 98
PD-L1 97
ERK 94
EGFR 94
MMP-9 93
p16 87
IFN 87
CD4 85
survivin 85
CD44 84
Ki-67 81
UTR 81
proteinase 3 81
MRI 80
matrix metalloproteinase 80
p27 80
HUC 77
CIS 75
tumor necrosis factor 73
PTEN 73
androgen receptor 72
pT3 71
histone 71
PD-1 70
cage 70
N-acetyltransferase 68
proliferating cell nuclear antigen 67
GSTT1 67
MMP-2 66
ERK1 65
p38 64
VEGF 63
collagen 62
STAT3 61
insulin 61
vimentin 60
TNF 59
erbB-2 58
N-cadherin 58
tyrosine kinase 57
kit 56
HER2 55
glycoprotein 54
hemoglobin 54
JNK 53
annexin V 53
cyclin E 52
interleukin-2 51
non-Hodgkin's lymphoma 51
epidermal growth factor 51
NAT1 51
fibronectin 51
IL-6 50
TERT 50
glutathione S-transferase 49
She 49
EMT 49
IL-2 48
caspase-9 48
IL-8 48
PARP 48
AS1 48
cancer susceptibility 47
COX-2 47
FDG 46
tumour suppressor 46
cyclooxygenase-2 46
telomeric 46
ras 46
CK20 46
NMR 45
c-myc 44
PIK3CA 44
CCK 43
endoplasmic reticulum 43
ROS 43
MMP9 42
cytochrome c 42
polypeptide 42
c-Myc 41
AP-1 41
CDK4 40
prostate-specific antigen 40
FISH 40
RB1 40
ATP 40
IL-10 39
ERBB2 39
cyclin 38
caspase-8 38
H-ras 38
lectin 37
histone deacetylase 37
Fas 37
CDKN2A 37
MYC 36
EZH2 36
osteosarcoma 36
GSTP1 36
bcl-2 36
EGF 36
XRCC1 36
IFN-gamma 36
xenobiotic 35
N-acetyltransferase 2 35
reserved 34
cytokeratin 34
GSH 34
Cyclin D1 33
carcinoembryonic antigen 33
cyclin B1 33
matrix protein 32
extracellular signal-regulated kinase 32
PSA 32
lymphoid 32
telomerase reverse transcriptase 31
prostate stem cell antigen 31
HRAS 31
MEK 31
GATA3 30
cytochrome P450 30
proto-oncogene 30
chemokine 30
TSC1 30
cadherin 30
P-glycoprotein 30
MDM2 30
albumin 30
THP 30
Men 29
mutant p53 29
metastasis suppressor 29
phosphatase 29
XPD 28
more...
Disease
bladder cancer 16431
cancer 7896
tumor 5785
carcinoma 1880
transitional cell carcinoma 884
carcinogenesis 842
prostate cancer 787
metastases 772
carcinoma in situ 570
tumorigenesis 545
tumor progression 537
lung cancer 532
tumor growth 519
carcinoma of the bladder 512
breast cancer 458
renal cell carcinoma 286
melanoma 259
transitional cell carcinoma of the bladder 251
gastric cancer 245
renal cancer 243
squamous cell carcinoma 238
Bladder 235
Bladder 234
Bladder 234
adenocarcinoma 216
colorectal cancer 191
leukemia 190
colon cancer 179
metastatic bladder cancer 169
cystitis 168
ureter 167
urethra 161
schistosomiasis 148
primary tumor 142
pancreatic cancer 139
ovarian cancer 139
dysplasia 138
Mycobacterium 137
aggressiveness 136
hepatocellular carcinoma 127
cervical cancer 122
invasive cancer 115
diabetes 108
lymphoma 102
tuberculosis 102
liver cancer 99
TCC 98
hydronephrosis 96
liver cancer 91
testicular cancer 90
skin cancer 86
non-small cell lung cancer 84
multiple myeloma 82
residual disease 80
incontinence 78
Hodgkin's disease 77
urinary tract infection 74
glioma 73
esophageal cancer 67
esophageal cancer 63
recurrent bladder cancer 61
retinoblastoma 60
sepsis 59
papilloma 58
lung carcinoma 56
incontinence 56
non-Hodgkin's lymphoma 56
sarcoma 56
rectal cancer 55
sepsis 54
type 2 diabetes 53
EMT 49
anemia 48
myelosuppression 48
AS1 48
head and neck cancer 47
solid tumor 43
thrombocytopenia 42
hypertension 42
papillary tumor 41
obesity 41
osteosarcoma 41
cancer recurrence 41
aggression 40
thyroid cancer 40
renal failure 40
uropathy 39
renal disease 39
glioblastoma 39
tumor angiogenesis 39
pelvic cancer 38
infectious diseases 37
cardiovascular disease 37
leukopenia 37
MCF 37
DDP 35
GSH 34
depression 34
laryngeal cancer 34
prostatitis 34
interstitial cystitis 34
hepatitis 33
uterus 32
PSA 32
BCG infection 32
West 32
cold 31
mesothelioma 31
pneumonia 31
endometrial cancer 31
pyelonephritis 30
bone metastases 30
neuroblastoma 30
lung metastases 30
neurogenic bladder 29
Prostate Cancer 29
XPD 29
bladder neoplasm 28
neutropenia 28
acute myeloid leukemia 26
APC 26
prostatic adenocarcinoma 25
ATM 25
epithelial ovarian cancer 25
squamous cell carcinoma of the bladder 24
penile cancer 24
hernia 24
neoplastic transformation 24
brain cancer 23
chronic cystitis 23
heart failure 23
ileus 23
Infection 23
urolithiasis 23
WT1 22
herpes simplex 22
myocardial infarction 22
laryngeal cancer 22
rheumatoid arthritis 22
Blocking 22
B-cell lymphoma 21
infestation 21
arthritis 21
SCID 21
Fanconi 21
tumor initiation 21
adenoma 21
Kaposi's sarcoma 21
HCG 21
metastatic renal cell carcinoma 20
HIV 20
prolapse 20
second cancer 20
vagina 19
xeroderma pigmentosum 19
cirrhosis 19
bowel obstruction 19
liver metastases 19
virus infection 19
basal cell carcinoma 19
more...
Symptom
pain 119
anesthesia 64
dysuria 50
nausea 43
nausea and vomiting 42
diarrhea 40
urinary frequency 35
vomiting 32
abdominal pain 32
anorexia 30
discomfort 29
discomfort 29
fatigue 26
weakness 15
pelvic pain 13
Ill 13
overweight 12
dyspnea 12
exhaustion 12
headache 11
flank pain 11
back pain 9
collapse 9
cachexia 9
seizures 8
analgesia 8
bladder pain 8
chills 8
cough 8
constipation 7
enuresis 7
starvation 6
low back pain 6
bone pain 6
erythema 5
hemiplegia 5
respiratory distress 5
arthralgia 5
colic 5
numbness 5
shortness of breath 4
frequent urination 4
tremor 4
HSA 4
abdominal discomfort 4
pneumaturia 4
cancer pain 4
sciatica 4
leg pain 3
spasm 3
dizziness 3
exertional dyspnea 3
paresthesia 3
asthenia 3
acidity 3
hemoptysis 3
skin irritation 3
lethargy 2
muscle cramps 2
neck pain 2
thinning 2
polydipsia 2
chest pain 2
Postoperative pain 2
cyanosis 2
splenomegaly 2
dysarthria 2
urethral discharge 2
angina 2
fever of unknown origin 2
Wind 2
consciousness disturbance 2
stigma 2
ataxia 2
hepatomegaly 2
myalgia 2
leg edema 2
cerebellar ataxia 2
oliguria 2
decreased appetite 1
physical symptom 1
shoulder pain 1
Urinary symptoms 1
ENT 1
tenesmus 1
incoordination 1
bloating 1
Scratch 1
Burning 1
groin pain 1
pain in the buttock 1
acute abdomen 1
physical appearance 1
tense 1
anal pain 1
lassitude 1
Pain of lower extremities 1
Purulent discharge 1
rigors 1
clubbing 1
adenitis 1
sleepiness 1
Chronic pelvic pain syndrome 1
dysesthesia 1
hyperemesis 1
intestinal bleeding 1
pallor 1
hopelessness 1
neuralgia 1
Acute urinary retention 1
Painless hematuria 1
bedwetting 1
right upper quadrant pain 1
syncope 1
blurred vision 1
Neuropathic pain 1
Physical findings 1
flushing 1
polyuria 1
clumsiness 1
night sweats 1
prostration 1
joint stiffness 1
hot flushes 1
wheezing 1
penile discharge 1
dry eye 1
chest tightness 1
breath holding 1
prostatism 1
neck stiffness 1
olfactory anesthesia 1
hypotonia 1
hypoproteinemia 1
vertigo 1
Flare 1
livedo 1
functional recovery 1
hypothermia 1
Drug
Adriamycin 80
IL-2 48
ROS 43
Monit 38
lysine 36
IFN-gamma 35
ascorbate 34
ROC 31
ADM 28
CTX 26
ALA 26
CSF 26
caffeine 25
vitamin E 24
Mutagen 24
BCG vaccine 24
GEO 20
Glutathione 19
Gefitinib 16
Photofrin 15
NBT 14
Dermatol 13
Valrubicin 11
Taxol 11
G-CSF 10
NADH 10
ABC 10
Arsenic trioxide 9
Rosiglitazone 9
ETS 8
Leaf 8
CTC 8
ADR 8
CTC 8
Paraffin 8
Gemzar 7
Pirarubicin 7
Bifidobacterium 7
HCG 7
Docetaxel 7
Gelatin 6
EE2 6
Bortezomib 6
Vitamin A 6
Isoniazid 6
Spectrum 6
Nitric Oxide 6
Etoposide 6
Fluorescein 6
Photofrin II 6
ENT 5
Angiotensin II 5
Asn 5
NVP 5
EPI 5
Hyaluronidase 5
CCL 5
Bestatin 5
Tocopherol 5
THF 5
Hyaluronidase 5
Mitomycin-C 5
VCR 5
Gallium nitrate 5
R1881 4
Heme 4
Herceptin 4
Taxotere 4
Everolimus 4
ICI 4
Oxaliplatin 4
Vitamin E 4
Indomethacin 4
Cardiovasc 4
Dial 4
Diamminedichloroplatinum 4
Fragment 4
uPA 4
CTX 4
Retinoic acid 4
Ipilimumab 4
EPA 4
Fluorescein 4
CTX 4
ACT 3
Portal 3
DMAP 3
G418 3
Zoledronic acid 3
Methyl aminolevulinate 3
-deoxyadenosine 3
BLM 3
MAP 3
CAM 3
TTC 3
CPT-11 3
Zoledronic acid 3
RFP 3
Check 2
Actos 2
PDL 2
Vitamin K2 2
TiO2 2
Hypaque 2
DHT 2
Albumin 2
ZnO 2
Xylocaine 2
pyridoxal phosphate 2
DHT 2
Sorafenib 2
CTA 2
Singular 2
Xylocaine 2
Erlotinib 2
Artesunate 2
MRC 2
CLS 2
Xylocaine 2
Dihydrotestosterone 2
Blenoxane 2
SBT 2
RAL 2
Emodin 2
Sunitinib malate 2
TAT 2
Fraction 2
Neocarzinostatin 2
PTH 2
Cetuximab 2
Tuberculin 2
Cremophor EL 2
Epigallocatechin 2
Alvimopan 2
Troglitazone 2
Hypaque 2
citric acid 2
Actos 2
VCR 2
TAC 2
Emodin 2
MDM 2
IFN-beta 2
Pemetrexed 2
Ganciclovir 2
Aredia 1
DMSA 1
Idarubicin 1
Levulan 1
EHDP 1
Gelfoam 1
PMPA 1
TAK 1
NH3 1
Capsicum 1
Pralatrexate 1
NOV 1
Donepezil 1
Apomorphine 1
PCB 1
more...
Enzyme
ERK 434
mitogen-activated protein kinase 252
luciferase 177
caspase-3 161
focal adhesion kinase 116
protein kinase 76
glutathione S-transferase 71
N-acetyltransferase 70
PARP 58
reverse transcriptase 41
peroxidase 41
caspase-9 38
prostate-specific antigen 38
MEK 37
NQO1 33
AMP-activated protein kinase 31
P-glycoprotein 30
cdc2 30
caspase-8 29
proteasome 28
ACS 27
catalase 27
superoxide dismutase 26
lactate dehydrogenase 26
APC 25
hyaluronidase 24
hyaluronidase 24
urokinase-type plasminogen activator 24
thymidine kinase 23
phosphatidylinositol 3-kinase 23
topoisomerase 22
alkaline phosphatase 22
RNase 22
RNase 20
topoisomerase 18
collagenase 17
DNA methyltransferase 17
AMPK 16
AMPK 16
GSK 16
phosphoinositide 3-kinase 15
protein kinase C 15
thymidylate synthase 14
UDP-glucuronosyltransferase 13
trypsin 13
beta-glucuronidase 13
demethylase 12
phospholipase C 12
MMP 12
NAT 12
beta-galactosidase 12
neuraminidase 11
endonuclease 10
alanine aminotransferase 10
matrix metalloproteinase 2 9
dihydrofolate reductase 9
acid phosphatase 9
glutathione peroxidase 9
ATPase 9
HK2 9
MMP-3 8
methylenetetrahydrofolate reductase 8
calcineurin 8
cathepsin D 8
methylenetetrahydrofolate reductase 8
granzyme B 8
ribonuclease 8
thymidine phosphorylase 8
ribonuclease 8
sulfatase 7
DNA polymerase 7
xanthine oxidase 7
RNA polymerase 7
ribonucleotide reductase 7
lipoxygenase 7
glutathione reductase 7
ribonucleotide reductase 7
matrix metalloproteinase 9 7
aryl hydrocarbon hydroxylase 6
histone demethylase 6
deoxycytidine kinase 6
PAH 6
succinate dehydrogenase 6
CYP3A4 6
prostate-specific membrane antigen 6
PAT 6
CD10 6
NADPH oxidase 6
glyceraldehyde-3-phosphate dehydrogenase 6
cathepsin B 6
carbonic anhydrase 5
methionine synthase 5
phosphodiesterase 5
caspase-7 5
ACE 5
caspase-7 5
elastase 5
methionine synthase 5
PDK1 5
kinesin 5
sialyltransferase 5
pyruvate kinase 5
sialyltransferase 5
ricin 5
sialyltransferase 5
glucose-6-phosphate dehydrogenase 5
15-hydroxyprostaglandin dehydrogenase 5
urease 4
gamma-glutamyl transpeptidase 4
urease 4
farnesyltransferase 4
glyceraldehyde-3-phosphate dehydrogenase 4
MDR 4
aldehyde dehydrogenase 4
farnesyltransferase 4
caspase-1 4
polo-like kinase 1 4
prostaglandin synthetase 4
transcriptase 4
CD13 4
diaphorase 4
aspartate aminotransferase 4
acetylcholinesterase 4
NADPH oxidase 4
phosphorylase 4
aldehyde dehydrogenase 4
DNase 4
pepsin 4
nicotinamide N-methyltransferase 4
peroxiredoxin 4
ornithine decarboxylase 3
TSP-1 3
matriptase 3
creatine kinase 3
paraoxonase 3
dihydropyrimidine dehydrogenase 3
diaphorase 3
arginine deiminase 3
ALDH 3
chloramphenicol acetyltransferase 3
glyceraldehyde-3-phosphate dehydrogenase 3
matriptase 3
adenosine deaminase 3
arylamine N-acetyltransferase 3
purine nucleoside phosphorylase 3
glyceraldehyde-3-phosphate dehydrogenase 3
kallikrein 3
IKK 3
aldehyde dehydrogenase 3
neutrophil elastase 3
lipase 3
GRK2 3
AGT 3
Protein 2 3
thrombin 3
hypoxanthine-guanine phosphoribosyltransferase 3
NADPH-diaphorase 3
protein phosphatase 2A 3
SMP 3
firefly luciferase 3
more...
Compound
DNA 1433
Dec 1111
Clin 939
BCG 469
water 393
oxygen 258
MTT 214
DDP 149
CCC 130
TNM 110
glucose 100
Adriamycin 99
TCC 98
sodium 97
calcium 96
creatinine 93
MBT 81
MMC 73
tyrosine 62
bromide 61
tryptophan 61
Gemcitabine 61
Gemcitabine 61
TNF 59
phosphate 59
lysine 58
Arsenic 58
tryptophan 57
tryptophan 57
tryptophan 57
acetate 57
iodine 55
Pac 54
GSH 50
GSH 50
arginine 49
nitrogen 49
MIC 48
iron 47
His 46
methionine 44
cysteine 44
ethanol 43
sulfate 43
urea 42
PEG 42
ATP 41
hydrogen 40
zinc 38
5-FU 38
nitric oxide 37
pyrene 36
nitrate 35
FANFT 35
galactose 34
salt 34
aniline 34
serine 33
hyaluronic acid 32
formamide 32
MEK 31
leucine 31
ADR 31
THP 30
chlorine 30
THP 30
retinoic acid 30
Curcumin 30
threonine 29
MDA 29
selenium 29
Methotrexate 28
silver 28
Optimal 27
PEG 27
N-acetylcysteine 27
CTX 26
ASA 26
ACS 25
ACS 25
PDT 25
caffeine 25
pyrimidine 24
cadmium 24
pyrimidine 24
potassium 23
Vimentin 22
benzene 22
alanine 22
retinol 21
formaldehyde 21
copper 21
H2O2 21
Metformin 20
Metformin 20
TOF 20
nicotinamide 20
CO2 20
glutamine 19
TPA 19
vitamin D 19
Asp 18
aluminum 18
DMSO 18
TPA 17
Phe 17
chromium 17
VP-16 16
SCC 16
Pioglitazone 16
Benzidine 16
NH2 16
ammonium 16
BLM 15
Thiotepa 15
ACI 15
PPD 15
methanol 15
NMP 15
pyridine 15
MMA 14
dimethylarsinic acid 14
MMA 14
phenol 14
dUTP 14
Epirubicin 14
acridine 14
PGE2 14
MMA 14
NBT 14
DMA 13
APO 13
Ile 13
DMA 13
proline 13
DMA 13
ADP 13
Paclitaxel 12
SDS 12
A 71 12
dimethylarsinic acid 12
COX 12
dimethylarsinic acid 12
TEPA 12
Photodyn 12
dimethylarsinic acid 12
Quercetin 12
dimethylarsinic acid 12
dimethylarsinic acid 12
NADPH 11
Photodyn 11
Photodyn 11
Photodyn 11
Photodyn 11
formaldehyde 11
Sulforaphane 11
NADPH 11
PPD 11
Photodyn 11
ADP-ribose 11
more...