Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: UMLS:C0004364 (autoimmune disease)
24,845 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein cytokine 1860 Sep 1518 CD4 1510 insulin 1049 Mol 935 autoantigen 777 lymphoid 730 HLA 718 CD8 653 IFN 635 thymus 629 collagen 624 interferon 593 IL-10 572 IL-6 548 IL-17 534 TNF 521 MHC 459 major histocompatibility complex 430 IFN-gamma 421 IL-4 413 tumor necrosis factor 392 IL-2 386 TCR 369 CD25 360 myelin basic protein 345 acetylcholine receptor 336 T cell receptor 335 Fas 314 gut 291 lacrimal 289 MHC class II 276 NOD 264 IgA 251 glycoprotein 250 rheumatoid factor 244 She 235 chemokine 227 CD28 220 axonal 216 TNF-alpha 196 human leukocyte antigen 190 interferon-gamma 184 CD20 178 histone 174 CD40 172 Cytokine 171 lipopolysaccharide 163 thyroglobulin 162 CTLA-4 160 HLA-DR 158 IgE 149 myelin oligodendrocyte glycoprotein 149 IL-23 146 IL-1 141 HLA class II 133 B10 131 SSA 130 TGF-beta 123 type I interferon 122 interleukin-6 121 MRI 117 LPS 116 TLR9 115 type II collagen 114 interleukin-2 114 CD86 113 BAFF 113 CD40L 110 MHC class I 106 DR3 104 C-reactive protein 104 SS-A 104 CD80 103 DBA 103 FOXP3 102 glutamic acid decarboxylase 99 proteolipid protein 99 SSB 98 autoimmune regulator 95 more...

Disease autoimmune disease 24845 systemic lupus erythematosus 4502 rheumatoid arthritis 2618 multiple sclerosis 2140 lupus 1963 diabetes 1739 cancer 1676 lupus 1605 arthritis 1255 encephalomyelitis 1253 type 1 diabetes 1045 myasthenia gravis 824 tumor 689 PSS 653 glomerulonephritis 547 vasculitis 529 Graves' disease 511 thrombocytopenia 472 antiphospholipid syndrome 440 celiac disease 431 Lupus 401 lupus nephritis 389 psoriasis 383 lymphoma 377 Hashimoto's thyroiditis 363 SLE 349 proteinuria 322 infectious diseases 318 immunodeficiency 315 scleroderma 314 virus infection 307 mimicry 275 primary biliary cirrhosis 273 NOD 264 renal disease 261 inflammatory bowel disease 260 hepatitis 259 hypothyroidism 236 nephritis 232 vitiligo 227 hypertension 225 atherosclerosis 224 thyroiditis 223 hyperthyroidism 222 uveitis 221 cardiovascular disease 220 xerostomia 219 pemphigus 218 lymphadenopathy 214 HIV 209 encephalitis 206 Crohn's disease 201 alopecia areata 200 anemia 199 autoimmune thyroid disease 195 dermatomyositis 195 idiopathic thrombocytopenic purpura 194 Sjogren's syndrome 194 autoimmune thyroiditis 186 asthma 185 Epstein 176 graft-versus-host disease 173 rash 152 obesity 150 skin disease 150 leukemia 149 liver disease 143 thrombocytopenic purpura 140 systemic disease 138 cirrhosis 135 pemphigoid 135 hyperglycemia 132 depression 131 interstitial lung disease 130 polymyositis 130 thymoma 130 tuberculosis 129 ulcerative colitis 124 myocarditis 122 immunopathology 121 more...

Symptom weakness 434 pain 302 fatigue 234 splenomegaly 152 dry eye 131 seizures 120 diarrhea 113 arthralgia 104 headache 100 abdominal pain 69 dyspnea 67 erythema 52 ataxia 51 cough 47 anesthesia 45 vomiting 42 neurological disability 41 myalgia 40 hepatosplenomegaly 33 nausea 30 chest pain 27 discomfort 26 discomfort 26 dysarthria 25 shortness of breath 23 Ill 22 chorea 22 collapse 21 hemoptysis 21 exhaustion 20 myoclonus 19 vertigo 19 anorexia 19 hepatomegaly 18 tremor 18 livedo 18 sleepiness 18 fever of unknown origin 18 cerebellar ataxia 17 spasticity 17 numbness 17 cachexia 17 insomnia 16 asthenia 15 respiratory distress 15 constipation 15 dizziness 14 paresthesia 13 chills 13 ophthalmoplegia 13 agitation 12 hoarseness 12 paresis 12 starvation 12 memory loss 12 back pain 12 polyuria 11 tinnitus 11 muscle stiffness 11 swollen joints 11 dystonia 10 polydipsia 10 angina 10 regurgitation 10 functional recovery 9 overweight 9 exertional dyspnea 9 lethargy 9 nausea and vomiting 8 Neuropathic pain 8 neck pain 7 thinning 7 stridor 7 spasm 7 catatonia 7 photophobia 6 acute stress 6 syncope 6 joint stiffness 6 analgesia 6 more...

Drug Dermatol 597 IFN-gamma 411 IL-2 389 CSF 124 Rituximab 94 Asthma 67 lysine 46 Cardiovasc 43 CTX 33 ROC 32 IFN-beta 24 ROS 24 CIA 23 Campath 20 Campath 20 Dial 19 ascorbate 18 Abatacept 17 Copaxone 16 Tacrolimus 15 Asn 15 MAP 15 BLyS 14 Estrogens 14 Prednisone 14 Natalizumab 13 vitamin E 12 Bifidobacterium 12 Nitric Oxide 11 ENT 11 Monit 11 p75 11 Belimumab 10 DNase I 10 Prednisolone 10 Thyroglobulin 9 G-CSF 9 IL-1ra 9 Gel 9 Histamine 9 Nephron 9 Tocilizumab 8 Infliximab 8 Infliximab 8 Albumin 8 Spectrum 8 Adalimumab 7 Methylprednisolone 7 lactose 7 CCL 7 Imiquimod 7 Nephron 7 CTX 6 ABC 6 Eculizumab 6 CTX 6 Retinoic acid 6 EDR 6 Spectrum 6 Leaf 6 DM1 6 Interferon beta 6 EPA 5 Vitamin B12 5 Daclizumab 5 ALA 5 Biopolymers 5 PDL 5 EE2 5 Mycophenolic acid 5 Alliance 5 BCG vaccine 4 NaI 4 ISP 4 CFS 4 Bortezomib 4 IL-11 4 Ipilimumab 4 ampicillin 4 caffeine 4 more...

Enzyme mitogen-activated protein kinase 171 thyroid peroxidase 133 focal adhesion kinase 130 peroxidase 120 ERK 102 transglutaminase 85 protein kinase 74 APC 72 proteasome 51 calcineurin 50 luciferase 49 caspase-3 48 thromboplastin 47 acetylcholinesterase 47 superoxide dismutase 42 ATPase 40 catalase 37 pyruvate dehydrogenase 37 thrombin 37 alanine aminotransferase 32 lactate dehydrogenase 32 reverse transcriptase 31 alkaline phosphatase 30 RNase 29 ACE 29 RNase 28 ACS 28 granzyme B 28 creatine kinase 27 trypsin 26 cholinesterase 26 protein kinase C 25 lysozyme 25 NADPH oxidase 24 NADPH oxidase 24 renin 24 RNA polymerase 24 collagenase 23 aspartate aminotransferase 23 IKK 22 MMP-3 21 phosphodiesterase 21 caspase-1 21 glutamate decarboxylase 20 NO synthase 20 DNase 19 peptidylarginine deiminase 19 caspase-8 18 21-hydroxylase 17 phosphoinositide 3-kinase 17 BMT 16 pyruvate dehydrogenase 16 tyrosinase 16 pyruvate dehydrogenase 16 MIP 15 cathepsin S 14 matrix metalloproteinase 9 13 CD10 13 glutathione S-transferase 13 indoleamine 2,3-dioxygenase 12 glutathione peroxidase 12 PARP 11 neutrophil elastase 11 beta-galactosidase 11 MEK 10 heme oxygenase 10 arginine deiminase 10 topoisomerase 10 topoisomerase 10 gamma-glutamyl transpeptidase 10 phosphatidylinositol 3-kinase 10 proteinase-3 10 phospholipase A2 9 p100 9 AST 9 phospholipase C 9 pepsin 9 ceruloplasmin 9 endonuclease 9 TSP-1 9 more...

Compound Clin 2692 Dec 1753 DNA 1509 TNF 521 calcium 293 glucose 252 oxygen 223 vitamin D 196 TSH 130 tyrosine 129 Thyroid 124 water 123 phosphate 122 nitric oxide 111 acetate 111 iodine 105 DBA 103 DBA 102 DBA 102 sodium 99 arginine 98 His 93 creatinine 87 ANA 86 ANA 86 lysine 77 iron 77 NKT 74 mercury 73 sulfate 67 Insulin 66 Vitamin D 61 HgCl2 59 nitrogen 59 leucine 57 ATP 57 tryptophan 57 tryptophan 56 tryptophan 54 tryptophan 54 potassium 52 BCR 51 Cardiol 50 alanine 50 ANCA 49 cysteine 49 Collagen 49 Cyclosporine 49 urea 49 CCP 47 salt 46 serine 46 zinc 46 cAMP 44 APS 43 Methotrexate 43 FK506 41 retinoic acid 40 PLP 38 galactose 38 ITP 36 Phe 36 hydrogen 34 PEG 34 CTX 33 Asp 30 SDS 29 ACS 28 glutamate 28 ACS 28 glutamine 27 bromide 27 GM1 26 ACTH 26 PMA 25 Estrogen 24 methionine 24 proline 24 Estrogen 23 GSH 23 more...

---