Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0004352 (autism)
 32,579 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors describe male monozygotic twins, Jon and Jay, who are concordant for autism and hyperlexia. Autism and mental retardation were diagnosed at the age of 2 years 5 months. Jay was the more advanced twin in motor co-ordination, attention span and receptive abilities, but had frequent tantrums. When psychologically assessed at 7 years 2 months, Jon showed borderline/severe mental retardation on the measure of non-verbal intelligence and Jay was moderately retarded. Their receptive language age was greater than their expressive language age: Jon's speech was less mature but more communicative and Jay's was perseverative and ritualistic. Even though Jon was the more mentally retarded twin, Jay was the more autistic in some behavioral aspects. These twins highlight the relationship between autism and hyperlexia.
 ...
PMID:Monozygotic twins concordant for autism and hyperlexia. 316 93

Would you entrust your brain to a bank? Well, many people do after they die, and such brain banks-often funded by government agencies or disease charities-are essential for neuroscience research. They collect and store the healthy and diseased brain specimens that neuroscientists need to explore neurological disorders such as Alzheimer's disease, schizophrenia and autism. Each brain bank typically has a limited supply of samples and tends to operate fairly independently. This means that researchers often have to trawl through numerous brain banks to find their desired specimens. Furthermore, there is a general shortage of brain samples. To help resolve these issues in the UK, James Ironside, professor of clinical neuropathology at the University of Edinburgh, was appointed in June as the director of the new UK Brain Banks Network. An expert in human prion diseases, particularly Creutzfeldt-Jakob disease (CJD), Ironside knows all about brain banks. He established the Brain and Tissue Bank at the UK's National CJD Surveillance Unit and is involved in the Sudden Death Brain and Tissue Bank at the University of Edinburgh. Jon Evans recently caught up with Ironside to discuss his new leadership position and how the brain network will benefit neuroscience research.
 ...
PMID:Straight talk with...James Ironside. [Interviewed by Jon Evans]. 1966 81

We compared the effectiveness and efficiency of a modified simple-conditional method and the conditional-only method for teaching receptive labeling of sight words. Jon, a 6-year-old boy diagnosed with autism spectrum disorder, participated. Across three comparative evaluations, the conditional-only method resulted in fewer sessions to mastery than a modified simple-conditional method. Textual responses emerged after Jon mastered the sight words as receptive labels. Practitioners should avoid teaching component simple discriminations as a strategy for facilitating conditional discrimination training in clinical practice.
 ...
PMID:A Comparison of Procedures for Teaching Receptive Labeling of Sight Words to a Child with Autism Spectrum Disorder. 2835 8