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Query: UMLS:C0004352 (autism)
 32,579 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The hypothesis that prognosis in autism would vary across subgroups was explored through cluster analysis of 52 cases. Four clusters related mainly to presence or absence of mutism, speech pathology, and lack of social responsiveness. Children who were mute and socially unresponsive on admission had particularly poor outcomes at follow-up 4.5 yr. later. For a third of the 35 subject followed, the Vineland Social Quotients (mean 46.0 for all subjects) had declined.
Percept Mot Skills 1989 Dec
PMID:The taxonomy and course of childhood autism. 262 42

This paper provides a methodological modification and reanalysis of the data presented by Hier, et al. in 1979 on the presence of unfavorable cerebral asymmetry in autistic patients. In contrast to prior findings, statistical significance was obtained, suggesting that it is premature to assert that such morphologic anomalies may be considered a risk factor in autism.
Percept Mot Skills 1981 Aug
PMID:Reversed cerebral asymmetries as a potential risk factor in autism: a reconsideration. 729 Aug 58

The relationship between age of walking and two factors of severity of intellectual disability and clinical types (autism, Down syndrome, epilepsy, and "residual") in children with mental retardation was investigated. Subjects were 118 children whose disabilities ranged from severe to mild. Measures by clinical type were significant, and the differences of any two clinical types except between children with epilepsy and the "residual" group were significant, but severity of intellectual disability was not significant. Most children with autism (27 subjects, 93%) walked by the normal time limit of 18 months. Only 3 children (11%) with Down syndrome began to walk within that limit, and 9 of them (33%) walked after 2 years of age. In the "residual" group (including children with epilepsy), 37 children (60%) walked within the normal limit but 15 (25%) only after 2 years of age.
Percept Mot Skills 1995 Apr
PMID:Factors affecting age of walking by children with mental retardation. 767 88

A pathognomic sign of mania, the Extrapolated Area Response (EAR), was described and explicated within the context of the TRAUT (Tripartite Classification of Autisms) system of categorizing Rorschach autisms. The EAR was interpreted as reflecting a person's tendency to expand his ambit beyond the confines of objective reality. Empirical validation is required.
Percept Mot Skills 1994 Jun
PMID:The extrapolated area response: a pathognomic sign of mania on the Rorschach? 808 74

The purpose of this study was to examine the serial information processing in adolescents with mental retardation, autism, and Down syndrome by using a serially patterned tracking task. Analyses indicated that 7 adolescents with mental retardation, 8 with autism, and 3 with Down syndrome had significantly slower and more variable simple reaction times than did 10 college students. Also, the autistic adolescents had significantly faster mean simple reaction time than those with Down syndrome. On a task of tracking serial light stimulation, mentally retarded adolescents had significantly faster reaction time than college students. The autistic subjects excessively had faster anticipatory reaction time than did the subjects in the other three groups. On the other hand, adolescents with Down syndrome had markedly slower and more variable reaction time than did adolescents with non-Down-syndrome mental retardation. As for motor organization of keystrokes on the tracking task, mentally retarded adolescents responded with six movements, in which these individuals pressed a series of keys 1, 2, 3, 4, 5, and 6, as a chunk, as exhibited by college students. Adolescents with autism and Down syndrome, however, did not produce this movement-output chunking.
Percept Mot Skills 1995 Dec
PMID:Simple reaction times and timing of serial reactions of adolescents with mental retardation, autism, and Down syndrome. 866 29

This study examined effects of practice on timing of serial reactions by 7 adolescents diagnosed with autism by using a task requiring they track a series of timed lights. The adolescents showed significantly slower and more variable mean simple reaction time than 10 normal control subjects of the same age. On a task of tracking a serial light stimulation for 4 days, on the other hand, significant effects of practice on timing of serial reactions were observed for mean serial reaction times of them. In addition, from individual variations in reaction times and anticipatory reaction times, four of seven subjects with autism showed significant effects of practice. Analysis suggested that these autistic adolescents may be chunking together the whole series of responses and are unable to coordinate the timing of individual responses with individual stimuli. Our data indicate that at least some adolescents with autism are able to form and utilise a motor program with practice.
Percept Mot Skills 1998 Apr
PMID:Practice and serial reaction time of adolescents with autism. 963 41

Children with attention deficit disorder and hyperactivity (ADHD) were compared with two other clinical groups, namely, children with autism and children with dyslexia, with respect to several peaks of the ERP. By using these other clinical groups, it was studied whether amplitude differences between children and ADHD and normal control children, which were found in an earlier study, were specific to children with ADHD. ERPs were measured in response to stimuli in an auditory and a visual oddball task. Only with respect to the P3 and Pz, measured in response to deviant auditory stimuli, did the children with ADHD show smaller amplitudes than both autistic children and those with dyslexia. It was concluded that a smaller amplitude of this peak is specific to children with ADHD.
Percept Mot Skills 1998 Dec
PMID:Are abnormal event-related potentials specific to children with ADHD? A comparison with two clinical groups. 988 81

Two clinical cases of children of 6 and 7 years are presented with their respective Rorschach records. The first case had a diagnosis of autism, the second of Pervasive Developmental Disorder Not Otherwise Specified. The modes of elaboration and responses to the ambiguous stimuli of the Rorschach test were compared with the clinical symptoms of the two subjects, which are centered on the two opposite poles of absence of imagination in the first case and distortion of the imaginative processes in the second.
Percept Mot Skills 1999 Dec
PMID:Disturbance of imagination and symbolization in pervasive developmental disorders: preliminary study utilizing the Rorschach Inkblot Test. 1066 26

Aim of the study was (1) to evaluate sensorimotor development of children with autism in comparison with that of children with developmental delay, (2) to verify the possible unevenness of the developmental profiles through correlations amongst domains and between domains and chronological age. 46 children with autism were compared with 45 children with developmental delay. Mean chronological age was 3.7 yr. in children with autism and 3.6 yr. in children with mental retardation. Mean mental age was 1.3 yr. in children with autism and 1.1 yr. in children with developmental delay. Ordinal scales of Uzgiris-Hunt show that the two groups score significantly differently on the scales of Object Permanence, Means-Ends, Operational Causality, and Spatial Relations and that scores were higher for the children with autism. The comparison made between the developmental levels of each group indicate that the sensorimotor profile in children with developmental delay is fairly homogeneous, while it appears uneven in autistic children, for whom Object Permanence appears to be the most advanced skill, Verbal and Gestural Imitation and Schemes for Relating to Objects the lowest. The results are in keeping with the assumption that the pivotal defect of autism is a deficit in social interactive skills.
Percept Mot Skills 2003 Jun
PMID:Profiles of sensorimotor development in children with autism and with developmental delay. 1292 62

This research analyzed gait in toddlers and tested the hypothesis that movement can be used as an early indicator of Autistic Disorder. It was proposed that an early identification method could indicate differences in the gait of toddlers with autism as opposed to those with typical development or with mental retardation. Observational methods were applied to retrospective home videos of 42 children after 6 mo. of independent walking. In particular, the Walking Observation Scale was used, which includes 11 items that analyze gait through three axes of foot movements, arm movements, and global movements. Analysis showed different distributions for the three groups, i.e., the autistic group differed from the other two on scores for the Walking Observation Scale and each axis. After 6 mo. of independent walking, different patterns in gait among groups were evident. These results agree with recently published evidence which acknowledges the importance of movement as an early indicator for differential diagnosis of autism.
Percept Mot Skills 2008 Feb
PMID:Analysis of toddlers' gait after six months of independent walking to identify autism: a preliminary study. 1845 75


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