Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
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Enzyme
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Query: UMLS:C0004352 (
autism
)
32,579
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
J
Autism
Dev Disord 1991
Sep
PMID:Brief report: violence in Asperger syndrome, a critique. 193 80
J
Autism
Dev Disord 1991
Sep
PMID:Brief report: effects of fenfluramine on communicative, stereotypic, and inappropriate behaviors of autistic-type mentally handicapped individuals. 193 81
J
Autism
Dev Disord 1991
Sep
PMID:Brief report: haloperidol treatment of trichotillomania in a boy with autism and mental retardation. 193 82
The study examined 75 autistic individuals who met DSM-III-R criteria for autistic disorder at 5 years of age. Diagnosis was based on information elicited using a standardized interview for
autism
. Two of 75 (2.7%) autistic subjects expressed the fragile X marker (Xq27.3) in 40% of cells counted and had other affected family members. Two additional subjects expressed the fragile X anomaly at low rates (1%). These rates are compared with those reported in other studies. Methodological differences, which may underlie the varying rates reported across studies, are discussed.
J Am Acad Child Adolesc Psychiatry 1991
Sep
PMID:The prevalence of fragile X in a sample of autistic individuals diagnosed using a standardized interview. 193 1
CD4+ (helper) T cells are a heterogenous population of lymphocytes including at least two distinct subpopulations. To investigate the possibility that immune abnormalities in some subjects with
autism
may involve abnormal distributions of CD4+ and/or CD8+ cells, (suppressor) T cells, peripheral blood lymphocytes of 25 autistic subjects were characterized with monoclonal antibodies and flow cytometry. The autistic subjects had a significantly lower percentage and number of CD4+ cells, a lower number of T cells (CD2+ cells) and B cells (CD20+ cells), and a lower percentage and number of total lymphocytes than siblings and normal subjects. The level of blood values for female subjects appeared lower than those for males as compared to normal subjects of the same sex. These results suggest that a decrease in CD4+ cells is associated with
autism
.
Immunol Lett 1990
Sep
PMID:CD4+ helper T cell depression in autism. 197 61
J
Autism
Dev Disord 1990
Sep
PMID:Treatment of destructive behaviors in persons with developmental disabilities. 210 92
Existing residential services for adults with
autism
vary in size, location, and source of funding. Most service options have been designed for individuals with handicaps other than
autism
and therefore have difficulty addressing the needs of all but the highest functioning autistic adults. This paper provides a review of the characteristics of
autism
that affect adaptation to residential settings. A description of existing residential options based on the combined experiences of Great Britain and North Carolina is presented, and directions for future research are then discussed.
J
Autism
Dev Disord 1990
Sep
PMID:The relationship between existing residential services and the needs of autistic adults. 222 13
Bittersweet Farms, a rural Ohio farm community for autistic adults, is presented. The land and facility are described, and the importance of certain elements of location, physical plant, and layout to the program model are discussed. The Bittersweet Farms program model is presented in detail as it applies to each aspect of rural, group living, and the contribution of each of its main features to the success of the Bittersweet Farms community is discussed.
J
Autism
Dev Disord 1990
Sep
PMID:Bittersweet farms. 222 14
Benhaven, a residential program of group homes providing intensive programming for autistic and neurologically impaired children, is described. Its major program factors of administration and management, treatment, support services, and family and community involvement are presented in detail. Benhaven's mission as an educational placement for preparing residents to function in the least restrictive environment on their way to future living situations is stressed.
J
Autism
Dev Disord 1990
Sep
PMID:Benhaven's residential program. 222 15
The service needs of those with
autism
and the response to those needs by the Eden Family of Programs are described. The Eden Family of Programs is described in detail, giving its history and discussing its participants, staff, schedules, programs, normalization, human rights, administration, and trustees.
J
Autism
Dev Disord 1990
Sep
PMID:Community-based services for children and adults with autism: the Eden Family of Programs. 222 16
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