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Query: UMLS:C0004352 (autism)
 32,579 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A follow-up survey was conducted on 201 young adults with autism who were 18 or older (mean age, 21.5). All had participated previously in intensive therapeutic camping or had therapeutic involvement at medical consultation agencies to evaluate their outcome. Their social outcome was better than that previously reported in Japan. Although 31.5% had shown marked deterioration during adolescence, 43.2% had shown marked improvement during that period. Possible factors contributing to these results are discussed.
J Autism Dev Disord 1992 Sep
PMID:A follow-up study of 201 children with autism in Kyushu and Yamaguchi areas, Japan. 138 89

Postural control was evaluated in samples of autistic, normal, and mentally retarded children in this pilot study using a recently developed, computerized posturographic procedure. A battery of postural positions was administered including postures involving some degree of "stress" (e.g., occluded vision or standing on pads). The postural patterns of children with autism differed from those observed in normal children, in mentally retarded children, and in adults with vestibular disorders. In comparison to normal children the autistic subjects were less likely to exhibit age-related changes in postural performance and postures were more variable and less stable with more lateral sway. Autistic subjects also exhibited a "paradoxical" response of greater stability with more "stressful" postures, putting excessive weight on one foot, one toe, or one heel. The implications for neuroanatomical models of autism are discussed.
J Autism Dev Disord 1992 Sep
PMID:Postural control in children with autism. 138 90

Hand preference and hand skill were assessed in 20 children with autism, 20 normal controls and 12 children with mental retardation. 90% of the normal controls and 92% of the children with mental retardation showed concordance for hand preference and hand skill (i.e. the preferred hand was also the more skillful), whereas only 50% of the children with autism showed concordance of preference and skill, the remaining 50% preferring to use the hand which was less skillful. Children with autism also showed a lesser degree of handedness and a lesser degree of consistency than the other groups, although this was unrelated to the discordance of skill and asymmetry. A developmental model of handedness is proposed in which the development of handedness as preference is ontogenetically prior to the development of handedness as skill asymmetry, such that in normal children the development of skill asymmetry occurs as a secondary consequence of the establishment of preference. The causal sequence is disrupted in autism, so that although preference is established, it does not subsequently result in concordant skill asymmetry.
Cortex 1992 Sep
PMID:Handedness in childhood autism shows a dissociation of skill and preference. 139 41

The purpose of the study was to determine whether the technique of task variation (with maintenance tasks interspersed) (TV) is more effective in the acquisition of gross motor skills for students with autism than a constant task (CT) condition in a physical education setting. Subjects were 12 male students with autism, ages 11 to 15 years. The study included pretest-posttest administration of the I CAN assessment of Gross Motor Skills to assess skills such as overhand throw, kick, and vertical jump. After a 6-week treatment period, the TV condition was significantly more effective than the CT condition, at the .05 level.
Except Child 1992 Sep
PMID:Teaching children with autism through task variation in physical education. 139 53


J Autism Dev Disord 1992 Sep
PMID:Questions about facilitated communication and autism. 140 Jan 2

Autism is a behavior disorder with genetic influences indicated from twin and family studies and from the co-occurrence of autism with known genetic disorders. Tuberous sclerosis complex (TSC) is a known genetic disorder with behavioral manifestations including autism. A literature review of these two disorders substantiates a significant association of autism and TSC with 17-58% of TSC subjects manifesting autism and 0.4-3% of autistic subjects having TSC. In initial data collected on 13 TSC probands and 14 autistic probands in our family study of autism and TSC, we identified 7 TSC subjects with autism. The seven TSC autistic probands are similar to non-TSC autistic probands on the Social and Communication domains of the Autism Diagnostic Inventory (ADI) (Le Couteur et al., 1989), but show fewer Repetitive Rituals. There are more male TSC probands with autism than female, despite an equal sex ratio among TSC probands. The TSC probands with autism have significantly more seizures and mental retardation than those without autism; however, the extent and etiology of associations require further study. Our preliminary findings suggest that a fruitful approach for delineating genetic influences in autism may come from further investigation of possible mechanisms underlying the association of autism and TSC.
J Autism Dev Disord 1992 Sep
PMID:Autism and tuberous sclerosis. 140 Jan 3

We take previously developed principles of a problem-solving approach to teaching pupils with (Jordan & Powell, 1990a, 1990b, 1991), and analyze their application within the normal teaching routine of a specialist school for such pupils. We note the kinds of pedagogical judgment made, and the structures needed by individual pupils to enable them to function as problem solvers. We identify reflection as a key factor in enhancing the potential of pupils as learners and discuss ways of increasing pupils' awareness of their own ways of handling learning situations. The study is set against the background of issues concerned with possibilities of developing a 'theory of mind' in pupils with autism.
J Autism Dev Disord 1992 Sep
PMID:Remediating the thinking of pupils with autism: principles into practice. 140 Jan 4

Previous research has suggested that there may be dysfunction in the control of the hypothalamic-pituitary-adrenal axis in autistic children. Both an abnormal cortisol circadian rhythm and failure to suppress cortisol secretion in response to dexamethasone have been reported. This study investigated the basal urinary cortisol circadian rhythm in a group of high-functioning children with autism and matched controls. No evidence was found for abnormal temporal placement of the circadian rhythm in the autistic group. There was a tendency towards cortisol hypersecretion during the day, predominantly in those autistic children who were integrated into the normal school system. While the temporal parameters of the cortisol circadian rhythm in these children with autism were probably normal, the tendency towards cortisol hypersecretion may indicate an environmental stress response in this group.
J Autism Dev Disord 1992 Sep
PMID:Urinary cortisol circadian rhythm in a group of high-functioning children with autism. 140 Jan 5


J Autism Dev Disord 1992 Sep
PMID:Does oxytocin deficiency mediate social deficits in autism? 140 Jan 6


J Autism Dev Disord 1992 Sep
PMID:Correction to previous evaluation of facilitated communication. 140 Jan 7


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